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Daylette is a combined contraceptive pill, used to help prevent pregnancy. It comes in 28-day strips, containing 24 active and 4 inactive tablets, and is taken every day without a break.

Daylette is not currently available using our confidential online pharmacy service. 

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PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.

This content was reviewed by a clinician on

19 April 2022
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 19 April 2022
Product information

Daylette is a combined hormonal birth control pill. It contains two active ingredients, ethinylestradiol and drospirenone, which help to prevent pregnancy. The pill is taken every day without a break; however the pack does contain both active and inactive pills, and these will need to be taken in a sequential order (24 active pills, followed by 4 inactive pills before the process is repeated).

In order to ready itself for pregnancy, the female reproductive system goes through a process called ovulation each month. This is where the ovary produces an egg, ready to be fertilised by male sperm. If the egg is successfully fertilised, it travels along the fallopian tubes to the uterus and implants on the uterine wall, where it develops into an embryo. If the egg is not fertilised, it simply breaks down in the uterus and exits the body along the womb lining during menstruation.

The hormones progesterone and oestrogen play an important role in this process. Levels of these hormones rise and fall at various times of the month, causing an egg to be released, and the uterine lining to thicken. When this lining becomes thick, a fertilised egg can implant on it.

The synthetic hormones in the combined pill work by mimicking progesterone and oestrogen, and supplementing them when levels naturally fall. By doing so, they prevent an egg from being released by the ovary. They also reduce the thickening of the wall of the uterus, making it harder for a fertilised egg to implant there; and increase the density of cervical fluid, to make it harder for sperm to travel to an egg.

When taken correctly, the combined pill is 99 percent effective at preventing pregnancy. If someone misses a pill when using Daylette, their level of protection will not fall provided they take the pill they have missed within 24 hours. However, if someone is more than 24 hours late, they may need to take extra precautions, and talk to their doctor for further guidance. The leaflet provided with the medicine contains more information on what to do.

If you aren’t currently taking the contraceptive pill, it’s best to talk to your GP in person and discuss which is the best option. They may need to undertake certain checks to make sure it is safe for you to take. In some cases, the progesterone only pill (mini pill) may be more suitable.

This pill is not available in the UK, so you can’t buy Daylette online from our pharmacy. However, there is a close alternative in Eloine. To access the pill quickly and easily, simply choose Eloine and fill in our medical questionnaire. Your answers will be checked by one of our registered healthcare professionals, who will issue an electronic prescription for your treatment if it is suitable. This will then be sent to our dispensing pharmacy, who will prepare your order and ship it to your home in secure packaging. Delivery on all items is made by next-day courier, so you can expect to receive your order in most cases in just 24 hours.

Page last reviewed:  19/04/2022

Take this medication according to your doctor’s instructions, and make sure you read the patient information leaflet before use.

  1. Each strip of 28 tablets contains: 24 active tablets, which are white; and 4 inactive tablets, which are green.
  2. You will need to take the 24 white tablets for the first 24 days of your cycle, followed by the 4 green tablets, then do the same when you move on to the next pack.
  3. Make sure you take the tablets according to the directions on the blister pack, starting with ‘1’.
  4. The pack comes with a weekdays sticker strip to help you keep track of when you have taken your pill.
  5. Withdrawal bleeding will usually occur within 2-3 days of taking the last white pill in the pack.
  6. Swallow your tablet whole with water.
  7. Take the tablet each day at the same time.
  8. Information on when you should start taking the pill, or what to do if you are switching from another pill to this one, is contained in the leaflet supplied.
  9. If you forget to take a green tablet, this will not make a difference to the effectiveness of the contraceptive, as these are placebo tablets. However, you should still throw away your unused green tablet so that you can easily keep track.
  10. If you forget to take a white tablet, but remember within 24 hours of when you were supposed to take it, you can take the forgotten tablet when you remember and carry on taking the tablet as normal. You will not be any less protected against pregnancy.
  11. If you forget to take a white tablet but remember 24 hours or more after missing the pill, your level of protection may be reduced. In this case, consult the leaflet for more guidance on what to do next. You may need to use extra protection (such as a condom) when having sex for the seven days following your missed pill, or speak to your doctor.
  12. Consult the leaflet for advice if you experience diarrhoea or are sick within 3-4 hours of taking the pill.
  13. Stop taking the pill and speak to your doctor if you become pregnant.

If you aren’t sure of anything, ask your doctor or pharmacist.

Page last reviewed:  19/04/2022
Side effects

Side effects

The risk of blood clots is higher in women who take combined hormonal contraception. If you notice any signs of a blood clot, such as swelling in the calf, chest pain or shortness of breath, you must seek medical attention as soon as possible. The leaflet contains more information on how to recognise a clot.

Any signs of a serious allergic reaction (such as hives, or swelling of the face, lips or throat) should be treated as a medical emergency.

Common (1 in 10 people or less):

Mood swings, headache, feeling sick, breast pain, irregular periods.

Uncommon (1 in 100 people or less):

Depression, anxiety, migraine, drowsiness, pins and needles, dizziness, varicose veins, high blood pressure, stomach problems, indigestion, diarrhoea, vomiting, rash, itching, acne, muscle cramps or pain, breast enlargement or benign lumps, thrush, vaginal discharge, unusual vaginal bleeding, vaginitis, hot flushes, loss of libido, vaginal dryness, water retention, sweating more than usual, drop in energy, weight gain.

Rare (1 in 1,000 people or less):

Fungal infection, anemia, thrombocythemia, allergic reaction, hormonal problems, increase or loss of appetite, failure to experience orgasm, sleeping problems, tremor, hyperactivity, dry eyes, eyelid inflammation, increased heartbeat, fainting, nosebleeds, hernia, bloatedness, bowel disorder, dry mouth, constipation, mouth infection, gallbladder problems, acne, hair loss, eczema, chloasma, excess hair growth, skin inflammation, skin photosensitivity, stretch marks on the skin, vulvovaginitis, pain during sex, breast cyst, withdrawal bleeding, abnormal womb growth, ovarian cyst, enlargement of the womb, blood clots (DVT, pulmonary embolism, heart attack, stroke, TIA), feeling unwell, weight loss.

Other side effects (frequency cannot be determined)

Hypersensitivity, erythema multiforme.

This is not an exhaustive list. Please consult the leaflet for more information on side effects.


Taking it with other medications

Tell your doctor about any other treatments you are currently using or have recently used during consultation. This is particularly important if you have taken, or are taking treatments for: epilepsy; tuberculosis; HIV or hepatitis C; or high blood pressure: or are taking St John’s wort.

Conditions to look out for

Do not take Daylette if you have or have ever had: a blood clot; a disorder which affects blood clotting, such as protein C or S deficiency; a higher risk of sustaining a blood clot due to being inactive for long periods, or are due to have an operation in hospital; a heart attack or stroke; angina; transient ischaemic attack; severe diabetes; very high blood pressure; very high cholesterol or triglycerides; hyperhomocysteinemia; migraine with aura; liver disease from which your liver function has not returned to normal; renal failure; a liver tumour; suspected breast cancer or cancer of the genital organs; unexplained vaginal bleeding; any allergies to soya or peanut, or any of the other ingredients in the medicine.

Your doctor may advise caution when using this pill, or advise against using it at all, if you: have just had a baby and are at increased risk of a blood clot; or if you have or have ever had: a family history of breast cancer; liver or gallbladder disease; diabetes; depression; Crohn’s or ulcerative colitis; lupus; haemolytic uraemic syndrome; sickle cell anaemia; a family history of hypertriglyceridemia; inflammation of the veins; varicose veins; epilepsy; any condition which first appeared during pregnancy; chloasma; or angioedema.

Pregnancy and breastfeeding

Do not use this treatment if you are pregnant or trying to get pregnant. It is not recommended that you take this pill if you are breastfeeding.

Driving and machinery

It is not likely that your capacity to drive or use machines will be affected by this pill.

Contraception and cancer risk

The risk of some types of cancer is thought to be slightly higher in women taking the combined pill. Refer to the leaflet for more information, or ask your prescriber.

Lactose intolerance and nut allergy

This treatment contains lactose and soya. Do not use it if you have any intolerances to sugars, or are allergic to soya or peanut, and speak to your doctor.

Regular check-ups

It’s important to have regular reviews with your GP or practice nurse when taking the pill, or using any other type of hormonal contraception. This should ideally be undertaken once a year, to ensure the contraception you are using is still suitable.

Page last reviewed:  19/04/2022

Can I still drink alcohol?

This pill should not be affected by alcohol, provided you continue to take it properly.


Will I still be able to drive?

Yes. Your capacity to drive or operate machines should not be affected by the medication.


Can I use this medicine while pregnant?

No. It is not suitable if you are pregnant, and is not recommended for use during breastfeeding.


How do I store it?

Keep in a safe place below 25°C, and out of the reach of children.


Am I allergic to anything in the medicine?

This pill contains ethinylestradiol, drospirenone, lactose monohydrate, maize starch, pregelatinised maize starch, macrogol poly (vinyl alcohol) grafted copolymer, magnesium stearate, poly (vinyl alcohol), titanium dioxide (E171), talc, macrogol 3350, lecithin (soya), microcrystalline cellulose, lactose anhydrous, colloidal anhydrous silica, indigo carmine (E132), quinolone yellow  (E104), iron oxide black (E172), and sunset yellow FCF (E110).


Do not take it if you are allergic to any of the above ingredients.


Is it available over-the-counter?

The pill is not available over the counter, and is prescription only. Before you take it, a doctor will need to ensure it is safe for you.


Is it right for me?

If you aren’t taking the pill currently or using any form of hormonal birth control, it’s better to talk to your GP or practice nurse. They will be able to advise you on the best option.


People already taking this pill, or looking to switch to it from another, can buy Daylette from our UK pharmacy by completing our online consultation. Click buy now and take our questionnaire to begin, and your responses will be viewed by one of our prescribing doctors. When approved, your prescription will be dispensed at our GPhC registered pharmacy, and shipped to you by next-day parcel.

Page last reviewed:  19/04/2022
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