• Ethinylestradiol/Norethisterone

Synphase is an oral pill used in birth control. The active constituents in it are artificial hormones which make the body forego ovulation.

Getting access to the pill needn’t be difficult, or take up valuable time. Our service allows you to get the treatment you need delivered to your door within one working day of approval from our registered practitioner.

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35mcg/0.5mg or 1mg

Each strip contains 21 tablets: twelve blue containing 500/35 micrograms of norethisterone/ethinylestradiol; and nine white containing 1mg/35 micrograms. Take these according to the arrows on the strip.

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Synphase is a contraceptive tablet made available in the UK by pharmaceutical giant Pfizer. The synthetic hormones in it, norethisterone and ethinylestradiol, provide birth control by simulating the action of progesterone and oestrogen, and preventing processes which make pregnancy possible from taking place.

  1. Easy to administer tablet
  2. Relieves menstrual unease
  3. Prevents pregnancy in 99% of cases

The product is a 21-day pill, which means that it is only applied for the first three weeks out of your regular periodic cycle. This window of application is then succeeded by seven pill-free days, with the treatment being applied again from the following week, and so on. It is a triphasic pill, which means that it contains three different types of tablet. These contain the same ingredients, but in varying levels. They must be taken in the sequence specified by the arrows on the pack in order to be effective.

Before pregnancy can start, the female body needs to undergo a series of preparations, which are managed by rising and falling hormones. One of the chief processes among these is ovulation, which involves the production and release of an egg. Following this, the egg is ready to be fertilised by sperm from the male partner, and travels to the uterus.

Another process managed by these hormones is the development of the endometrium, otherwise known as the lining of the uterine wall. This allows the fertilised egg to implant in the uterus and begin the next stage of its growth into an embryo. At a certain time each month, these hormones also cause this lining to be shed through menstrual bleeding.

In Synphase, the functioning components supplement the levels of these hormones as they fall naturally. This makes the body think that it does need to make the above preparations for pregnancy. Therefore, ovulation does not take place and an egg is not produced; and the quality of the uterine wall lining is changed so that it cannot house a fertilised egg. They also increase the thickness of mucus in the cervix, and this makes it harder for sperm to travel through to an egg and inseminate it.

You can buy Synphase from our UK-based pharmacy, and have it delivered within just one working day. Take our questionnaire, and one of our registered practitioners will review the answers you give. Following approval, your order will be sent to our pharmacy who will dispense and ship your medicines via next-day courier.

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How to use Synphase

Use this pill exactly as your doctor has instructed, and read the directions in the patient information leaflet fully prior to first use. This will help you to maximise the effectiveness of the treatment, and lessen the potential for side effects.

  1. Apply as per your prescriber's directions.
  2. This, typically, will be one pill per day for the first three weeks of your menstrual cycle.
  3. Remember to take the pill at the same time each day.
  4. After three weeks, have seven pill-free days.
  5. The following week, begin treatment again and continue this process.
  6. When taking your tablet, swallow them whole, and with water if necessary.
  7. The best time to start taking this pill is on the first day of your period, unless stated otherwise in the patient information leaflet.
  8. Synphase is a triphasic pill, and must therefore be taken in the correct order. Strips containing the tablets are marked with arrows and days of the week to help you keep track of your treatment.
  9. If you miss your dose, consult the leaflet provided for information on what you should do. Contact your doctor or family planning nurse if you require further guidance.
  10. Never take more than your prescriber tells you to.

These directions are for your information only, and do not serve as a substitute for the more detailed instructions supplied with the treatment. Refer to these before use.

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Synphase side effects

Be aware that some side effects may require immediate medical attention. These include those which may indicate an allergic reaction, such as: sudden wheeziness, difficulty breathing, respiratory pain, fever, sudden swelling, rash or itching, particularly if it affects the whole body; or those which could be signs of a blood clot: coughing up blood, swelling or tenderness in your stomach, pain in your chest which is sudden, sharp or severe, shortness of breath or finding breathing painful, inflamed veins in your legs, first attack of migraine or a migraine which is worse than normal, dizziness or feeling faint, or problems with sight or speech.

Frequency unknown:
Increased blood pressure, feeling or being sick, stomach upsets, fluctuations in weight, changes in appetite, headaches, breast tenderness, depression, changes in sex drive, irregular vaginal bleeding, or womb disorders.

A more detailed list of side effects can be found in the patient information leaflet.

Taking it with other medicines

Let your doctor know if you are using any other treatments, as they may interfere with the function of the pill or vice versa. Synphase may interact with the following products: carbamazepine, oxacarbazepine, phenytoin, phenobarbital, primidone, topiramate, St John’s wort, nelfinavir, nevirapine, ritonavir, rifabutin, rifampicin, griseofulvin, or modafinil.

Conditions to look out for

Some conditions may mean that this pill is not safe for you to use. Do not take it if you have or ever have had: blood clots or a family history of clotting problems; a heart attack or stroke; angina; high fat levels in your blood; cancer of the breast, cervix, vagina or womb; pruritus, jaundice, or pemphigoid gestationis during a previous pregnancy; severe chronic liver disease; unexplained vaginal bleeding; or bad migraines.

You should also tell your doctor if you have a history of the following: epilepsy; asthma; migraines; headaches; visual disturbances; cardiovascular disease; high blood pressure; kidney disease; diabetes; multiple sclerosis; tetany; breast problems; varicose veins; liver dysfunction; severe depression; fibroids in your uterus; irregular periods; sharp abdominal pain; skin pigmentation disorders related to pregnancy; gallstones; sickle-cell anaemia; otosclerosis; or porphyria.

Q&A: our Synphase discussion forum

Can I still drink alcohol?

Yes. You can drink alcohol while using this drug.

Will I still be able to drive?

Yes, provided you experience no side effects which may impair your capacity to drive. If you do, you should not drive and seek medical attention right away.

Can I take the medicine while pregnant?

No. It is not safe for those who are pregnant, or suspect they might be. It is also not recommended for women who are breastfeeding. You doctor may suggest an alternative form of contraception in this case.

How should I store it?

Keep it in safe, dry environment, below 25°C and away from direct sunlight.

Am I allergic to anything in the medicine?

Synphase tablets contain: norethisterone, ethinylestradiol, maize starch, polyvidone, lactose, magnesium stearate and colouring E132 (blue pills only). Do not take them if you are allergic to any of these ingredients.

Is it available over-the-counter?

This contraceptive pill is a prescription-only treatment, meaning that you can only buy it after consulting with a doctor. Our registered practitioners can issue a prescription based on the answers you supply to our medical questionnaire.

Is it right for me?

Fill in our short questionnaire to find out. Your case will be reviewed by a GMC-registered doctor, who will only approve your medicine if they are convinced it is safe for you. Confirmed orders are sent to our UK-based dispensing pharmacy, then shipped directly to your home via secure 24-hour courier service.

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We promise to keep your details secure and private. We will never sell your information or share it with third parties. Whatever treatment you buy online from us, we will send in plain, unmarked packaging via our secure courier service.

Delivery on all items is included in the price. After your order has been dispatched, you’ll be supplied with a tracking number, allowing you to follow the progress of your items every step of the way. We deliver to anywhere in the UK, so whether you’re in London, Birmingham, Manchester, Glasgow or Cardiff, your order will be at your door within just 24 hours of approval from our doctor.

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