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Yiznell is a combined hormonal contraceptive pill. It contains synthetic versions of oestrogen and progesterone. 

If you want to buy Yiznell online, you can do so using our online pharmacy. Simply take our quick and simple contraception questionnaire. Pending approval from a GMC-qualified doctor or a GPhC-registered prescriber, your order will be shipped using a 24-hour courier.

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The price below are inclusive of your consultation, prescription, the medicine itself and secure next-day shipping from our UK pharmacy.

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Yiznell is a combined hormonal contraceptive pill. It contains synthetic versions of oestrogen and progesterone. 

If you want to buy Yiznell online, you can do so using our online pharmacy. Simply take our quick and simple contraception questionnaire. Pending approval from a GMC-qualified doctor or a GPhC-registered prescriber, your order will be shipped using a 24-hour courier.

This content was reviewed by a clinician on

26 January 2022
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 26 January 2022
Product information

Yiznell is a combined hormonal contraceptive treatment. It contains two synthetic versions of the hormones oestrogen and progesterone. Oestrogen and progesterone are hormones naturally produced in the female body and they play several key reproductive functions. Without them, conception could not occur. 

If certain hormones are supplemented at certain times throughout the menstrual cycle, this affects the usual processes that make pregnancy possible. 

These types of contraceptive treatments are 99% effective when used correctly (for example when pills are never missed and they are taken at the same time each day). To understand how these types of treatments work, it is first necessary to understand a little bit about the roles of certain hormones in the reproductive cycle. 

Ovulation is the process where an egg is released by the ovaries. There are two ovaries, and typically the release of an egg will alternate between the two. This is known as ovulation. Once an egg becomes fertilised by a single sperm cell, it will then begin a journey along the fallopian tubes until it reaches the endometrium. Here, it attaches itself to the mucus membrane, which is thickened at this particular time to assist this process. After this process, known as implantation, the egg will grow into an embryo and subsequently develop into a baby. 

Oestrogen and progesterone play vital roles in this cycle. When oestrogen levels rise in the body, the process of ovulation begins. Oestrogen is also responsible for maintaining and thickening the uterus lining. Progesterone helps to maintain the lining in the latter half of the reproductive process. If fertilisation does not occur, the egg and endometrial wall breaks down and is shed in a period. 

The synthetic hormones in this treatment prevent an egg from being released, and therefore stop ovulation from occuring. Yiznell also works by thickening the mucus found in the womb canal, which makes the journey of sperm much harder to complete. Finally, it stop the lining of the womb from becoming thicker. So even if a fertilised egg can reach the final stage of the cycle, implantation, it will have a difficult time actually implanting itself in the womb. 

Combined contraceptive methods are a popular choice among women seeking contraception for the first time. One disadvantage is that patients must remember to take the pill over the 21 day period and ensure they do not run out. 

If you want to order Yiznell online, you can do so by filling out our medical questionnaire which will then be reviewed by a registered doctor or prescriber. Pending their approval, your treatment will be shipped using secure 24-hour courier.

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Page last reviewed:  26/01/2022

While the method of taking combined contraceptive medication is usually similar and straightforward, it is still important you take it exactly as instructed and prescribed. Speak with your own doctor if you need more advice about this. 

  1. Yiznell comes in strips of 21. 
  2. Each strip has markings of the days of the week. 
  3. Take one pill a day, at the same time every day. 
  4. Do this for 21 consecutive, uninterrupted days. 
  5. Use the markings on the pack to help you. 
  6. Once the 21 day course is complete, stop taking Yiznell for a subsequent seven days. 
  7. During this seven day break, you may experience ‘withdrawal bleeding.’ This is normal and is similar to a period. 
  8. After the seven day break, on the eighth day, begin the 21 day course again. 
  9. If you forget to take a pill, and you remember within 12 hours, then contraception is still covered. 
  10. If you remember after 12 hours then contraception cannot be guaranteed. 
  11. Remember to take what would have been the following tablet the next day. 
  12. You should use additional contraceptive protection, such as a condom, for the next seven days if you’re more than 12 hours late taking a missed pill.
  13. Consult the leaflet for more on what to do if you miss a pill.

Speak with your doctor if you need more advice.

Page last reviewed:  26/01/2022
Side effects

Not everybody will experience side effects when taking combined contraceptive treatments, but it is important to be aware of what they look like and seek medical attention when and if necessary. 

Common side effects (between 1 and 10 in every 100 users):  

Depressed mood, headache, migraine, nausea  breast pain, breast tenderness, menstrual disorders, bleeding between periods, thick, whitish vaginal discharge and/or vaginal yeast infection. 

Uncommon side effects (between 1 and 10 in every 1,000 users):  

Breast enlargement, altered interest in sex, high blood pressure, low blood pressure, vomiting, diarrhoea, acne, severe itching, skin rash, hair loss (alopecia), vaginal infection, fluid retention  and/or body weight changes. 

Rare side effects (between 1 and 10 in every 10,000 users):  

Hearing impairment, asthma, breast secretion, allergic reactions, skin conditions such as erythema nodosum or erythema multiforme, harmful blood clots in a vein or artery. 

This is not an exhaustive list of side effects associated with this treatment. We recommend familiarising yourself with the patient information leaflet and particularly reading about blood clots and their association with combined contraceptive treatments. 


Taking it with other medications

Always make your doctor aware of any medications you are currently taking. This may influence their decisions about prescribing treatment. Some medications, when taken together, can interfere with each other’s effectiveness. 

Particularly make your doctor aware if you take any treatments for epilepsy (primidone or phenytoin, for example), any treatment for tuberculosis, HIV or hepatitis treatments, any treatment for arthritis, treatment for blood pressure in the vessels of the lungs and, finally, the herbal treatment St. John’s Wort. 

Conditions to look out for

Not everyone can take Yiznell. Be sure to make your doctor or prescriber aware of any medical conditions you have or have had. 

You must tell your doctor if you have ever suffered from any type of blood clot, but particularly of the legs (deep vein thrombosis) or the lungs, or if you know you have a disorder that may cause or impact on clotting such as protein C deficiency, protein S deficiency, antithrombin-III deficiency, Factor V Leiden or antiphospholipid antibodies, if you have ever had a heart attack or stroke, angina pectoris, transient ischaemic attack, severe diabetes with damage to the blood vessels, high blood pressure, high levels of fat in the body, high cholesterol levels, a condition known as hyperhomocysteinemia, a type of migraine called ‘migraine with aura,’ any form of liver disease or reduced liver function, kidney failure or limited kidney function, a tumour in the liver, breast cancer or cancer of the genital area,  unexplained vaginal bleeding, if you are allergic to the active ingredients (ethinylestradiol or drospirenone) and if you have hepatitis C. 

Pregnancy and breastfeeding

Do not take Yiznell if you are pregnant. While it is unlikely, if you become pregnant while taking this treatment you must stop the course immediately and consult with your doctor. If you decide you want to conceive a child, you can stop taking Yiznell at any time. It does not interfere with long-term fertility. Taking this medication is generally not advised while breastfeeding so we recommend pursuing a different form of contraception for as long as you breastfeed. 

Driving and machinery 

This treatment should not interfere with the ability to drive in the vast majority of instances. However, if you do experience a severe migraine - which is a listed possible side effect - this has the potential to impact on your ability to safely operate a vehicle or machinery. If you do experience a migraine speak with your doctor for advice as soon as you can. 

Contraception and cancer

Breast cancer has been observed more often in women who take this combined contraception than those who do not. However, it is not known whether this is a direct cause of the treatment. Read about this further in the patient information leaflet, or speak with your doctor for more advice. 

Lactose intolerance 

Lactose is a listed ingredient found in Yiznell. Therefore it may not be suitable for those who are intolerant to dairy.

Page last reviewed:  26/01/2022

Can I still drink alcohol? 

You can still drink alcohol while taking this treatment, but always drink responsibly. 

Will I still be able to drive? 

Yes, in the vast majority of instances this treatment should not interfere with the ability to drive. If you do experience any side effects which inhibit this ability, like a severe migraine for example, then we recommend speaking with your own doctor. 

Can I take the medication while pregnant? 

Under no circumstances should this treatment be taken while pregnant, nor is it recommended for people who are breastfeeding. If you become pregnant while taking Yiznell, while it is very unlikely, you must stop taking it immediately. 

Am I allergic to anything in the medication? 

The active substances are drospirenone and ethinylestradiol. Each tablet contains 3 milligrams drospirenone and 0.03 milligrams ethinylestradiol.  

Other ingredients (excipients) are lactose monohydrate, corn starch, pregelatinised maize starch, magnesium stearate, croscarmellose sodium, hypromellose (E464), macrogol, talc (E553b), titanium dioxide (E 171), iron oxide, yellow (E 172). 

Is it available over the counter? 

Yiznell is a prescription only medication. 

Is it right for me? 

If you find yourself asking this question, or it’s the first time you’ve considered this method of combined contraception, then we recommend making an appointment with your GP or a reproductive specialist. They will be able to offer the right advice for you, and speak more with you about this treatment. 

How can I buy Yiznell online?

You can access a repeat prescription with us. Simply fill out our consultative questionnaire to have your case reviewed by one of our qualified medical practitioners. Pending clinical approval, your order will be processed in our UK-based pharmacy and shipped using our secure, 24-hour courier. 

Page last reviewed:  26/01/2022
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