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Alphaderm is a cream treatment for skin conditions, such as eczema. It reduces inflammation and itching.

We do not provide this item through our service. Speak to your GP if you have eczema and want to find out more about this treatment.

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PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.

This content was reviewed by a clinician on

21 September 2020
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 21 September 2020
Product information

Alphaderm is a skin cream used to relieve inflammatory conditions, including psoriasis, and is made by Alliance Pharmaceuticals. It contains two functioning constituents, which are a corticosteroid called hydrocortisone, and urea, which helps the skin to retain moisture. Currently, Alphaderm is only available to buy in the UK with a prescription.

  1. Contains a corticosteroid ingredient
  2. Maintains skin moisture and softness
  3. Simple to apply

Eczema is a common skin condition, characterised by dry skin. This can result in redness, cracks, and irritation. Affected regions can vary significantly in size. Most commonly, it occurs on the hands, arms, and legs, but it can also affect the face and scalp. The condition typically goes through periods of flare-up and remission.

What causes eczema is unclear. However, associations have been drawn between eczema and allergic conditions such as hay fever and asthma. Flare-ups can sometimes be triggered by contact with an allergen, be it food, pollen or cosmetic products like shampoos. It can also get worse in periods of hormonal fluctuation, such as during menstruation or pregnancy.

There is at present no way of curing eczema, however several treatments and self-help techniques can assist in relieving symptoms. For instance, avoiding triggers can help, as can taking measures to limit further damage to the skin through scratching (such as gently rubbing the irritated area instead).

When treating the condition, a doctor will usually assess its severity before advising which type of medication (if necessary) to use. In Alphaderm, which is available to buy online through our secure prescription service, there are two main ingredients, which are a corticosteroid called hydrocortisone, and urea. Hydrocortisone works by reducing the activity of inflammatory chemicals in the body, thus helping to soothe irritation; whereas urea is a chemical which occurs naturally in the skin, helping it to retain water and preventing it from drying out.

If you have eczema symptoms and are seeking treatment for the first time, you should see your GP in person. Following assessment of your symptoms, they will be able to suggest an appropriate cream or lotion where required.

Please note we do not provide this medication through our service.

Page last reviewed:  21/09/2020

Make sure you follow the directions issued by your prescriber when using this treatment, and that you read the instructions provided in the patient information leaflet carefully beforehand. This will help you to lower the risk of side effects, and maximise the efficacy of the product.

  1. Use as directed.
  2. In cases of an eczema flare up, this will likely be a thin layer applied twice a day for the duration specified by your prescriber.
  3. The cream should not be used for long periods. Contact your doctor if symptoms persist.
  4. Wash and dry the affected region prior to use.
  5. Never exceed the prescribed dose.
  6. If you forget to use it, simply apply the cream at the next scheduled time and carry on the course as normal.

For more detailed instructions, please refer to the leaflet provided.

Page last reviewed:  21/09/2020
Please read the patient information leaflet for this medicine fully before use:

Alphaderm 1%/10%

Side effects & Warnings

It is crucial to be aware of the side effects associated with this item, so that you can seek medical advice if necessary. Tell your doctor if you notice any signs of an allergic reaction.

Frequency not stated:

Irritation of cracked or moist skin, infections spreading or becoming worse, red marks or lines appearing on the skin, inflammation of the skin, acne, or a slight loss of pigment in the skin where the cream is used.

More information on side effects can be found in the leaflet supplied.

Taking it with other medicines

Your doctor needs to know if you are using any other treatments, as they may affect the function of this product.

Conditions to look out for

It may not be suitable for those with acne, or a skin infection.

Pregnancy and breastfeeding

Check with your doctor before using Alphaderm if you are pregnant, breastfeeding or trying to conceive.

Page last reviewed:  21/09/2020
Please read the patient information leaflet for this medicine fully before use:

Alphaderm 1%/10%


Can I still drink alcohol?

It is not likely that the function of this treatment will be affected by alcohol.

Will I still be able to drive?

Yes. Your capacity to drive should not be inhibited by the use of this medication.

Can I use this medicine while pregnant?

If you are pregnant or breastfeeding, let your prescriber know, as this product may be unsuitable for you to use.

How do I store it?

In a safe place, below 25°C.

Am I allergic to anything in the medicine?

This cream contains: hydrocortisone, urea, white soft paraffin, isopropyl myristate, maize starch, glyceryl tribehenate, palmitic acid, sorbitan laurate and polyoxyethylene fatty glyceride.

Do not use it if you are allergic to any of the constituents listed.

Is it available over-the-counter?

You can only buy Alphaderm with a prescription. This is so that a doctor can make sure it is suitable for you prior to use.

Is it right for me?

The eczema medication you use will be determined during a face-to-face consultation with your GP. If you have symptoms but are not currently using treatment, you should make an appointment with them, so that they can examine your case and give you advice on which (if any) product to use.

Page last reviewed:  21/09/2020 is rated 4.9 out of 5 by 3129 customers on TrustPilot!
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