With so many different medicines for erectile dysfunction available, it can be difficult knowing which one is going to most beneficial or effective. Your doctor should be able to help you find and settle on the right treatment.

However, for those who want to know more about MUSE specifically, we thought it might be useful to put together a guide to why some people might prefer this treatment over others.

In this article we’ll cover:

How fast does MUSE work?

One of the main advantages of using MUSE is that it can produce an erection within 5-10 minutes of administration; which puts it among the fastest ED treatments.

This is because it is inserted directly into the urethra in the form of a suppository, and absorbed through tissue; unlike tablets which need to be ingested in the stomach and taken up into the bloodstream.

How well does MUSE work?

In a clinical study for MUSE, 65.9% of participants achieved an erection that was satisfactory in a clinical setting. Of these 64.9% said that they had successful intercourse after self-administering the treatment at home.

In another study, which examined patients who had previously found intracavernosal injection of PGE1 ineffective, 58% of participants achieved an erection which was suitable for intercourse having been given MUSE in a clinical environment, and 47% of them reported that they had been successful with MUSE in a home environment.

Efficacy rates for PDE5 inhibitor (tablet) treatments tend to range from 60-80%, depending on the medicine and the dosage used. For most men, these remain the first choice of treatment; but MUSE might be effective in cases where these do not work as well.

How easy is it to administer MUSE?

Some men may find MUSE less straightforward than simply swallowing a tablet, particularly during the first few times of use. However, men using MUSE are likely to become more used to administering it the more times they do so.

Many men may also be more comfortable using MUSE than they would be injecting themselves with a needle. Although the procedure of inserting a suppository into the urethra is a delicate one, there is obviously less of a risk of bruising or scarring at the application site that potentially comes with an injection.

The risk of certain side effects is also lower than some other treatments. In the patient information leaflet, prolonged erections is listed as an uncommon side effect of MUSE (affecting less than 1 in 100 patients). In the leaflet for the injectable version of alprostadil, this is listed as a common side effect (affecting less than 1 in 100 patients).

Can MUSE be considered if other treatments are not suitable?

Yes. Most people who turn to MUSE will be doing so because oral tablets have not worked for them, or are not suitable. This can be due to a number of factors; such as if they are allergic to an ingredient in the tablet.

Someone who has used an oral treatment might also have experienced side effects, and be keen to try something else. An alternative treatment such as MUSE might be suggested by a doctor in such cases.

If you have tried tablets for erectile dysfunction and they have not worked, or would like to know more about whether MUSE might be more suitable for you, we recommend you speak to your doctor.

Page last reviewed:  24/08/2018