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Diflucan is a treatment for yeast infections, such as vaginal thrush. It belongs to a category of medicines called antifungals, and contains the active component fluconazole.

At, our private online consultation allows you to buy Diflucan in a safe and secure way. Complete a short health questionnaire to place your treatment order. 

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Contains 150mg of fluconazole. For vaginal thrush, a course may consist of a dose of one capsule.

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Diflucan is a treatment for yeast infections, such as vaginal thrush. It belongs to a category of medicines called antifungals, and contains the active component fluconazole.

At, our private online consultation allows you to buy Diflucan in a safe and secure way. Complete a short health questionnaire to place your treatment order. 

This content was reviewed by a clinician on

11 March 2021
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 11 March 2021
Product information

Diflucan is a capsule medicine used to treat yeast infections, including vaginal thrush. It is a brand of fluconazole, an antifungal agent, and is manufactured by Pfizer. A doctor may prescribe Diflucan as a single dose in cases of thrush, making it a convenient and minimally-invasive form of treatment for the condition.

  1. Fights thrush fast
  2. Single-dose treatment
  3. Popular brand made by Pfizer

What does Diflucan treat?

Vaginal thrush is caused by a yeast called Candida albicans. This particular yeast is common, and can be found living harmlessly on the tissue of many people. It is thought that nearly half of women will have some levels of Candida present in their vagina. In most cases, the fungus is harmless and kept at manageable levels by other friendly bacteria.

However, the balance of bacteria, yeasts and fungi in the body is a delicate one, and can sometimes become upset. Thrush infections occur when, for one reason or another, levels of Candida rise, resulting in symptoms. These may include redness and itching around the vagina, painful sensations during urination or sexual intercourse, and in less frequent cases, slight amounts of white discharge.

Why does thrush develop?

There are a number of possible contributing factors when it comes to thrush. While bacteria passed between sexual partners can certainly be one cause, infection can also be brought on by: using certain types of soap or detergent when washing underwear; or the recent use of antibiotics. Women of just about any age can get thrush, but it is more common among those who have a weak immune system, or diabetes. Pregnant women are also at increased risk of developing the condition.

How does Diflucan work to treat thrush?

Treatment for thrush is typically issued in the form of antifungal medicine. Diflucan is different to other forms of medication, as it is a tablet, and most other thrush products are vaginal creams. The active ingredient in this item is fluconazole, which works by compromising the structure of fungal cells.

To ensure their own stability, fungal cells require the activity of ergosterol, a chemical which they self-produce. Fluconazole prevents the generation of this sterol, which causes gaps to emerge in cell membranes. Soon after this, the cells become no longer able to function, and perish. Once they have depleted in number, symptoms of the infection begin to pass.

Diflucan’s active ingredient - fluconazole

The antifungal element in Diflucan is a substance called fluconazole. This works by tempering levels of fungi in the body, and helping to re-establish bacterial balance.

A number of different bacteria and fungi live on and inside the body. Some perform a positive function in maintaining a person’s health; whereas others can cause illness but may be harmless in smaller numbers. Candida albicans is an example of this latter type. It is a very common form of yeast, which is only usually present in small amounts as certain types of bacteria work to keep it in check.

However, sometimes various factors can result in a person’s bacterial levels becoming imbalanced, and this can cause levels of Candida to rise. When this occurs, symptoms of an infection may appear.

When applied, fluconazole functions by tackling the cells of the fungus causing the infection. It penetrates the cells’ defences, and disables their ability to produce ergosterol, a vital component of their structure. Once the cell is no longer able to release this sterol, they begin to break down and eventually die, thereby stopping the infection.

Can I buy Diflucan online?

If you are trying to find the right vaginal thrush treatment to suit your needs, can help. Diflucan is a branded medication which you can buy from our UK pharmacy. We work with GMC-registered doctors to provide a secure and private consultation service. After placing your order, you will be presented with a questionnaire. The answers you supply will be reviewed by one of our physicians. If the product is safe, a prescription will be made up for you, which will be fulfilled by our GPhC-registered pharmacy and carefully delivered to you by tracked courier.

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Page last reviewed:  11/03/2021


It is crucial when using any form of medicine to follow the directions specified by your doctor, and adhere to the instructions provided in the patient information leaflet. Doing so will help to optimise the efficacy of the medication and reduce the likelihood of side effects.

  1. Take your Diflucan capsule as directed by your prescriber. For vaginal thrush, this may be one single dose, swallowed with water.
  2. The capsule can be taken with or without food.
  3. If your doctor has prescribed a continuous course, complete it as instructed unless they tell you otherwise. Never exceed the amount prescribed by your doctor, and never make up for a missed dose with a double dose. Continue your course as normal.

These directions are only intended as an informational guide. For detailed instructions, speak to your doctor or refer to the supplied leaflet.

Download Diflucan patient information leaflet

Page last reviewed:  11/03/2021
Please read the patient information leaflet for this medicine fully before use:

Diflucan 150mg

Side effects & Warnings

Side effects

Most medicines, whether they are prescription, non-prescription or remedial, pose a risk of possible side effects. Diflucan is no different. If you experience anything unusual or become concerned, seek immediate medical attention. Side effects associated with this item include:

Common (1 in 10 people or more):

Headache, skin rash, nausea, vomiting, stomach pain, diarrhoea, or abnormal liver function test results.

Uncommon (1 in 100 people or less):

Fatigue, fever, convulsions, tremor, vertigo, loss of appetite, constipation, flatulence, muscle pain, liver problems, jaundice, anaemia, itching, or muscle pain or weakness.

Rare (1 in 1000 people or less):

Seizures, alopecia, liver failure or inflammation, fever, abnormal bleeding, irregular heartbeat.

The information provided here is only a guide, and does not list all of the side effects which this product may cause. A more detailed list can be located in the patient information leaflet.

Taking it with other medicines

When undergoing consultation for any medication, you should inform your prescriber of any other treatments you are using or have recently used.

Diflucan may interact with the following: Cisapride, terfenadine or astemizole, pimozide, quinidine or calcium channel blockers, rifampicin, antibiotics such as rifabutin, azithromycin or erythromycin, diuretics, losartan, warfarin or coumarin-type anticoagulant medicines, benzodiazepines, oral sulfonylureas, phenytoin or carbamazepine, cyclosporine, everolimus, sirolimus or tacrolimus, theophylline, zidovudine (also known as AZT or saquinavir), prednisone, oral contraceptives, opioids such as alfentanil, fentanyl and methadone, non-steroidal anti-inflammatory medicines such as aspirin or celecoxib, amitriptyline and nortriptyline, amphotericin B, voriconazole, cyclophosphamide and vinca alkaloids, halofantrine, HMG-CoA reductase inhibitors, and vitamin A.

Conditions to look out for

You should inform your doctor prior to using this treatment if you have a history of any of the following, as they may affect your suitability for the medicine: more than two occurrences of thrush in the last six months; liver or kidney problems; a chronic illness; a sexually transmitted disease; irregular vaginal bleeding or a blood stained discharge; vaginal sores, ulcers or blisters; lower abdominal pain or burning on passing urine.

Additionally, men should not use this medicine if: their sexual partner does not have vaginal thrush; they have penile sores, ulcers or blisters; they have an abnormal penile discharge; their penis has started to smell; or if they have pain on passing urine.

Pregnancy and breastfeeding

Check with your doctor before using this medicine if you are pregnant, breastfeeding or trying for a baby.

Driving and using machines

This medication may cause side effects that interfere with driving and machine use ability. Wait until you know how Diflucan affects you before attempting to drive or use machines.

Lactose intolerance

This product contains lactose, so you should inform your prescriber if you have an intolerance to any sugars.

Page last reviewed:  11/03/2021
Please read the patient information leaflet for this medicine fully before use:

Diflucan 150mg


Can I still drink alcohol?

This medicine has no known interactions with alcohol.

Will I still be able to drive?

If you experience side effects which may make driving dangerous, you should avoid doing so and seek medical advice.

Can I take the medicine while pregnant?

No. Diflucan is not suitable for those who are pregnant or breastfeeding.

How should I store it?

Store the medicine below room temperature, sealed, and away from excessive sources of moisture or light.

Am I allergic to anything in the medicine?

Diflucan capsules contain fluconazole, lactose monohydrate, microcrystalline cellulose, maize starch, sodium laurilsulfate, colloidal anhydrous silica and magnesium stearate. Avoid using this medicine if you are allergic to any of the above.

Is it available over-the-counter?

No. You can only buy Diflucan in the UK with a prescription.

Is it right for me?

We can help you find out if this product is the right treatment for you. Simply choose your item, and fill in our short medical assessment. Following approval from our doctor, it takes just one working day for us to dispense and deliver your medicine.

Page last reviewed:  11/03/2021 is rated 4.9 out of 5 by 3131 customers on TrustPilot!
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