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Miconazole Nitrate

Gyno-Daktarin Cream is an antifungal treatment for vaginal thrush, made by Janssen Pharmaceutica. It is dispensed using a vaginally-inserted applicator.

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Gyno-Daktarin Cream0.02

Follow the dose prescribed by your doctor. This cream contains 20mg of miconazole nitrate per 1g and is usually applied once a day before bedtime, for up to seven days. 

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Gyno-Daktarin Cream is an antifungal treatment for vaginal thrush, made by Janssen Pharmaceutica. It is dispensed using a vaginally-inserted applicator.

At, we can help you get discreet treatment fast, from the convenience of your own home.

This content was reviewed by a clinician on

11 March 2021
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 11 March 2021
Product information

Gyno-Daktarin Cream is a medication for vaginal thrush. It can be applied as a pessary, which means that it is dispensed directly into the vagina; or it can be distributed on external vaginal infections directly. The core ingredient of the medicine is an antifungal agent called miconazole nitrate. When treating vaginal thrush the dose is usually once per night for up to 7 days.

  1. Pessary alternative to oral tablets
  2. Straight-forward application 
  3. For vaginal thrush

Vaginal thrush is a condition which almost every woman will experience at some point in their adult lives. It is typified by redness and raw sensations of irritation in or around the vagina, discomfort during urination or penetrative sex, and in fewer cases, the presence of a thick, slightly off-white discharge. The condition is usually not serious, but it can be a source of distraction and frustration for those experiencing it.

It is caused by the Candida albicans species of yeasts. This is commonly found in the vagina, but poses no problems when present in smaller amounts. Some natural bacteria work to monitor and manage Candida, so that it does not rise above a certain level. However, the yeast can flourish and grow under certain conditions, most typically when levels of opposing, positive bacteria are depleted. When Candida becomes too prominent in the vagina of the host, an infection can develop, resulting in the symptoms described above.

The NHS treats as many as 80,000 new cases of vaginal thrush every year. The infection is more likely to occur in people who are immunocompromised, have diabetes, or are pregnant, but can affect women of any age.

There are several reasons why thrush may develop in an individual. The yeast can be passed from one individual to another through sex, but it can also be caused by washing with certain types of soap or detergent, as well as through the use of antibiotic medication (which can alter the body’s bacterial balance).

Miconazole nitrate, which is the operative component of Gyno-Daktarin, relieves symptoms by breaking down the defences of fungal cells. To maintain their form, these cells produce an alcoholic substance called ergosterol. This sterol contributes to their membrane strength and structural stability. Miconazole inhibits the cell’s capacity to produce this substance, thereby creating holes in the membrane of the cell, and causing the contents to flow out. This eliminates the cells, and cures the infection.

You can purchase vaginal thrush treatment online using our simple consultation process. Just fill out our online assessment after choosing your item, and a doctor will examine your answers. Once your order has been approved, our UK-based pharmacy will send it to you via next day courier.

Active Ingredient

The antifungal substance in Gyno-Daktarin is a compound called miconazole nitrate. It was developed by Belgian firm Janssen Pharmaceutica, and is applied to the treatment of various types of fungal infection.

This agent gets to the root of infection by neutralising the cells of the offending fungus. Candida albicans is a yeast which is widely present in people’s bodies. In smaller numbers, the yeast is harmless, and adequately managed by the body’s own bacteria. However, in certain conditions the presence of Candida can grow, and this is when the yeast becomes abrasive. High levels of it in the vagina can lead to a thrush infection.

Miconazole destroys fungal cells by preventing from producing a vital self-sustaining component, called ergosterol. Once this process has taken place, the cells can no longer sustain structural consistency. This causes them to die out, and then the infection goes away.

Find out if Gyno-Daktarin can help you by taking just a few minutes to fill in our online health survey. Once our doctor has confirmed the medication is safe for you, a prescription will be issued, and your medicine will be sent via tracked next-day delivery.

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Page last reviewed:  11/03/2021


In order to maximise the effectiveness of this treatment and lessen the risk of side effects, administer as directed by your prescriber, and adhere to the guidelines found in the patient information leaflet.

  1. Apply as directed. This may be one dose per night for up to seven days.
  2. For infections inside the vagina:
  3. Break the seal on the tube with the cap provided.
  4. Screw the green-banded applicator into the tube, yellow side first.
  5. Give the tube a squeeze and stop once the plunger reaches the stop mark.
  6. The applicator should now be full. Unscrew this and fasten the cap back onto the tube.
  7. Lie on a comfortable surface, on your back with your knees bent and your legs spread apart.
  8. Carefully insert the yellow end of the applicator into your vagina.
  9. Depress the plunger gently, fully expelling the cream into your vagina.
  10. Once completed, dispose of the applicator responsibly.

For external infections of the vagina:

  1. Apply a thin layer of cream to the affected area.

In both cases:

  1. Wash your hands afterwards. 
  2. Repeat the dose as prescribed.
  3. Never exceed the amount prescribed for you by our doctor.

These directions are intended solely as a guide. Read the instructions provided with the medicine thoroughly prior to first use.

Download Gyno-Daktarin patient information leaflet

Page last reviewed:  11/03/2021
Please read the patient information leaflet for this medicine fully before use:

Gyno-Daktarin Cream 0.02

Side effects & Warnings

Side effects

Not everyone will experience side effects when using this medication, but it is important to speak to a doctor if you notice anything at all unusual during treatment. Seek medical advice you experience any of the following: continued feelings of irritation or itching around the application site; rashes or hives; headaches; urinary pain; vaginal bleeding; or facial flushing.

This is not a complete account of the side effects this medicine may cause. A more detailed list can be found in the information leaflet supplied.

Taking it with other medicines

Inform your doctor of any other medications you are currently using when undergoing consultation for this product. The use of anticoagulants, oral diabetes medicine, calcium channel blockers, phenytoin, medicines to lower cholesterol or various types of barrier contraceptive may make this item unsuitable.

Never use more than one vaginal thrush treatment at any one time without express permission from your doctor.

Conditions to look out for

Let your prescriber know if you a history of any medical conditions, or are allergic to anything.

Pregnancy and breastfeeding

If you are pregnant, planning on becoming pregnant or breastfeeding, you should check with your doctor before using this item.

Page last reviewed:  11/03/2021
Please read the patient information leaflet for this medicine fully before use:

Gyno-Daktarin Cream 0.02


Can I still drink alcohol?

This treatment is not thought to interact with alcohol.

Will I still be able to drive?

This product should not hinder your capacity to drive, but if you notice any side effects which might, avoid doing so and contact your doctor.

Can I take the medicine while pregnant?

You should only use this cream while pregnant or breastfeeding if your doctor thinks it is safe to do so.

How should I store it?

Store this product in a safe place below 25 degrees. Make sure the seal is intact before using it for the first time.

Am I allergic to anything in the medicine?

This item contains miconazole nitrate, purified water, PEG-6, PEG-32, glycol stearate, oleoyl macroglycerides, liquid paraffin, benzoic acid (E210) and butylated hydroxyanisole (E320). You should not use it if you suspect you may be allergic to any of the above.

Is it available over-the-counter?

No. You will need a prescription to buy Gyno-Daktarin from any UK pharmacy. Our GMC-registered doctors are on hand to review your case and issue a prescription for this product if they think it is suitable for you.

Is it right for me?

Find out by taking our online questionnaire. One of our physicians will assess your answers and following confirmation, we’ll dispatch your item right away. Our pharmacy uses a tracked courier service, who will have your medicine at your door by the following working day.

Page last reviewed:  11/03/2021 is rated 4.9 out of 5 by 3131 customers on TrustPilot!
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