• Atovaquone/Proguanil

Malarone is an antimalarial drug made by GlaxoSmithKline. It contains two functioning agents which both treat and prevent the disease.

If you’re heading off to a tropical location and are looking for reliable protection against malaria, can help. All orders are checked by registered doctors and shipped from our pharmacy by next-day courier.

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Each tablet contains 250mg of atovaquone and 100mg of proguanil. The prescribed amount for the prevention of malaria may be one tablet per day for a specified period; whereas for the treatment of active malaria, this may be one dose of four tablets a day for three days.

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Malarone is an antimalarial drug, which can be used to either medicate the disease while it is active, or prevent an infection from starting. The manufacturers of Malarone are GlaxoSmithKline, and thanks to its combination of two active ingredients, the treatment is adept at combatting more resilient strains of the disease.

  1. Efficient at fighting resilient strains
  2. Branded treatment
  3. Take one tablet a day for prevention

Malaria is a condition caused by the plasmodium parasite, of which there are four different types. Of the four, plasmodium falciparum malaria is the most deadly, and the variety which Malarone is intended to treat. The parasite is transferred to humans through mosquito bites, and establishes itself in the body by taking over cells in the bloodstream.

Once it has spread to a sufficient degree, symptoms begin to appear; usually after a period of 7-18 days, but this may be longer. These may include diarrhoea, fever and headaches at first. However, serious cases can result in organ failure, and even prove fatal. For this reason, the prevention and treatment of malaria for those travelling to regions where the disease is present should be taken very seriously.

It is estimated that approximately 200 million people worldwide will become infected with the disease, and that two thirds of a million of these will result in death; making malaria one of the world’s most dangerous conditions. During the planning stages of your trip, it is important to find out about the presence of malaria in the place you are visiting, so that you can take the appropriate treatment.

The active constituents in Malarone are progunail and atovaquone. They prevent the parasite from reproducing in the body by inhibiting its capacity to generate a self-sustaining enzyme. This enzyme, which is called dihydrofolate reductase, enables the parasite to copy itself through the development of new DNA material. By blocking the production of this substance, Malarone weakens the parasite. This then leaves it open to the attack from the immune system, which deals with what remains of the parasite.

Before buying Malarone online in the UK, it is important to make sure you are doing so from a GPhC-registered pharmacy. This will help to protect you against fraudulent sellers and help you get the medication you need in a secure manner. Every order made through is evaluated by a practising doctor, who will only prescribe a medication if they are satisfied that it is safe.

Filling in our questionnaire takes just a few minutes. Once your order has been approved by our doctor, our pharmacy will ship it to you via 24-hour courier.

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How to use Malarone

Always make sure you follow the directions your prescribed has issued to you, and read the patient information leaflet prior to use. This will help to minimise the risk of side effects and increase the effectiveness of the drug.

  1. Administer as directed by your prescriber.
  2. For the prevention of malaria, this might be one tablet taken once a day.
  3. The course should commence 1-2 days before travel and continue throughout.
  4. Treatment should be continued for 7 days following return from an infected area.
  5. For the treatment of the disease while active, 4 tablets once a day for three days may be the prescribed dose. In this case, however, self-treatment is not an option and hospital admission will be necessary.
  6. Swallow tablets whole with food where possible.
  7. Take Malarone at the same time each day.
  8. Do not take more than advised by your prescriber.
  9. If you miss a dose, you should not double up on your next one, but do contact your doctor for advice on what to do next.

These instructions are intended only as a guide, and do not constitute detailed directions. Refer to the leaflet supplied prior to using this medicine.

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Malarone side effects

If you notice any signs of an allergic reaction, skin rash with blisters, Stevens-Johnson syndrome, or any other side effects which concern you, contact your doctor right away.

Very common (1 in 10 people or more):
Diarrhoea, headache, nausea and vomiting, stomach pain.

Common (1 in 10 people or less):
Dizziness, sleeping problems, depression, loss of appetite, fever, rash, or cough.

Uncommon (1 in 100 people or less):
Anxiety, irregular heartbeat, swelling and redness of the mouth, or hair loss.

Rare (1 in 1,000 people or less):
Seeing or hearing things which are not there.

This is not a comprehensive list of the side effects this product may cause. A more detailed account can be located in the patient information leaflet.

Taking it with other medicines

Tell your prescriber if you are taking any other medicines during consultation. Malarone may affect the function of or be compromised by the following treatments: metoclopramide; antibiotics such as tetracycline, rifampicin and rifabutin; efavirenz or other medications for HIV; warfarin and other blood thinning agents; or etoposide.

Conditions to look out for

Disclose your medical history to your prescriber before use. Malarone may not be suitable for you if you have ever had kidney disease.

Q&A: our Malarone discussion forum

Can I still drink alcohol?

Yes. Alcohol is not thought to affect the way this drug works. However, it is advisable to only drink in sensible amounts, as the the medicine needs to be taken responsibly and on a regular basis.

Will I still be able to drive?

Some users have reported feelings of dizziness when taking this treatment. If you feel as though you may be unable to drive safely, avoid doing so and seek immediate medical attention.

Can I use this medicine while pregnant?

This product is not recommended for those who are breastfeeding, and a doctor may advise against using it if you are pregnant, or suspect you might be.

How do I store it?

In a safe environment out of the reach of children.

Am I allergic to anything in the medicine?

Malarone contains atovaquone, progunail, poloxamer 188, microcrystalline cellulose, hydroxypropyl cellulose, povidone K30, hypromellose, sodium starch glycollate (Type A), magnesium stearate, titanium dioxide (E171), iron oxide red (E172), macrogol 400 and polyethylene glycol 8000.

Is it available over-the-counter?

You will need a prescription to buy Malarone in the UK. Our doctors can issue a prescription based on the information you provide during consultation.

Is it right for me?

Let us help you find out. Take our health questionnaire today, and one of our doctors will examine your answers. If your medication is suitable, your order will be prepared and dispatched from our UK-based pharmacy. Each order made through our site is delivered by 24-hour courier, so you can begin using your treatment the following working day.

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We promise to keep your details secure and private. We will never sell your information or share it with third parties. Whatever treatment you buy online from us, we will send in plain, unmarked packaging via our secure courier service.

Delivery on all items is included in the price. After your order has been dispatched, you’ll be supplied with a tracking number, allowing you to follow the progress of your items every step of the way. We deliver to anywhere in the UK, so whether you’re in London, Birmingham, Manchester, Glasgow or Cardiff, your order will be at your door within just 24 hours of approval from our doctor.

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