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Venlalic XL

Venlafaxine hydrochloride

Venlalic is an antidepressant manufactured by Pfizer. It is typically prescribed to treat depression, anxiety and the various conditions that are associated with them.

If you have any concerns about your symptoms, we provide a video consultation service with our fully registered doctors that is available from 9am to 5pm, Monday to Friday. We are able to provide advice, fit notes, access to specialists and prescriptions that allow you to buy Venlalic online from our UK pharmacy.

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This page is only to be used as an informative guide for this treatment. The price above is indicative of the cost of the treatment alone, and does not include the consultation fee (£25), prescribing fee (£9) and the 24 hour delivery fee (£5.50) if you choose to have the treatment dispensed at our pharmacy.

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£ 21

This page is only to be used as an informative guide for this treatment. The price above is indicative of the cost of the treatment alone, and does not include the consultation fee (£25), prescribing fee (£9) and the 24 hour delivery fee (£5.50) if you choose to have the treatment dispensed at our pharmacy.

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This page is only to be used as an informative guide for this treatment. The price above is indicative of the cost of the treatment alone, and does not include the consultation fee (£25), prescribing fee (£9) and the 24 hour delivery fee (£5.50) if you choose to have the treatment dispensed at our pharmacy.

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Venlalic is an antidepressant manufactured by Pfizer. It is typically prescribed to treat depression, anxiety and the various conditions that are associated with them.

If you have any concerns about your symptoms, we provide a video consultation service with our fully registered doctors that is available from 9am to 5pm, Monday to Friday. We are able to provide advice, fit notes, access to specialists and prescriptions that allow you to buy Venlalic online from our UK pharmacy.

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Product information

Venlalic is an SNRI, or serotonin norepinephrine reuptake inhibitor. It’s an antidepressant that is usually prescribed to treat depression, anxiety, OCD (obsessive compulsive disorder), PTSD (post traumatic stress disorder) and social anxiety disorder. Venlalic contains the active ingredient venlafaxine hydrochloride.

How many people are affected by mental health in the UK? 

Mental health affects one in four people in the UK to a significant enough degree that they speak to their doctor. There are many different forms of mental illness, ranging from generalised anxiety disorder to PTSD to OCD.

Everyone at some point in their lives will feel down. A low mood is a perfectly normal experience that does not necessarily mean that a person is suffering from depression. Should this low mood be severe enough, or lasts for an extended period of time, then this is likely to be diagnosed as depression. Depression can range from generally feeling low, a lack of motivation to get out of bed or an inability to enjoy life’s pleasures, to more serious symptoms of suicidal thoughts and self-harm. There are many causes of depression, such as grief, financial problems, relationship issues or unemployment. There may also be genetic factors at play, but sometimes there isn’t a straightforward explanation why someone might suffer from depression.

What is generalised anxiety disorder?

Generalised anxiety disorder is a serious condition that can have significant health consequences if not dealt with. It can manifest in different forms and may be unique to the individual experiencing it. Anxiety is often present in various mental health conditions, such as PTSD or OCD, and can result in unpleasant feelings like panic attacks, where a feeling of overwhelming dread is coupled with hyperventilation and fear.

What are some OCD behaviours? 

OCD is a condition where certain thoughts compel obsessive behaviour. This may be the continuous checking that a door is locked preventing you from leaving the house, the compulsion to touch objects in a specific order and a specific number of times or, at worst, troubling thoughts that you can't move past.

What is PTSD?

PTSD is a relatively common response to life-threatening situations, such as violence or serious illness. This trauma can lead to the reliving of the experience through flashbacks or vivid nightmares. It is thought that as many as a third of those who have survived traumatic events will experience PTSD in some form. 

Social anxiety disorder, which some refer to as social phobia, is the feeling of fear that can come with social interactions. It is a common experience in adolescence but is more likely to affect the elderly. It is a profound fear of everyday social situations and may result in the person being unable to leave the house. Panic attacks, palpitations and low self-esteem are common symptoms. 

Treating depression

There are many tools that may help you deal with these conditions, ranging from talking therapies to medication. Counselling may be enough for some, but CBT (cognitive behavioural therapy) has been found to be particularly effective for anxiety disorders. For others, medication may be the best route. A doctor will be able to suggest the best course of action by discussing your symptoms with you and their causes. Our GMC registered doctors are able to provide a prescription for you to buy Venlalic from our GPhC regulated pharmacy should they decide this is right for you.

Venlalic is an SNRI, which is different from SSRI antidepressants. Both types work by limiting the reabsorption of serotonin, allowing levels to remain high in the brain. Serotonin is a feel-good hormone that has been heavily linked to mood. SNRI antidepressants, however, also increase the level of norepinephrine in the brain, which affects motivation and social skills. This is particularly helpful for those suffering from social anxiety disorder.

If you wish to use our video consultation service, our registered doctors can provide advice, fit notes, access to specialists and prescriptions that are required for you to buy Venlalic from our UK pharmacy. The service is available from the hours of 9.30am to 4.30pm, Monday to Friday.

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Page last reviewed:  17/09/2020
Directions

Always follow the instructions given for your treatment by your prescribing clinician. Not doing so can increase the likelihood of side effects, and mean you may not benefit fully from the treatment. It is also advised that you read the patient information leaflet fully before taking Venlalic.

  • Dosage will depend on the severity of your symptoms
  • The starting dosage is usually 75mg
  • This may be increased to as much as 375mg for depression if required
  • For anxiety disorders the maximum dosage is 225mg
  • Should be taken at approximately the same time everyday
  • Take after breakfast to limit the risk of nausea
  • Taken with water
  • Never crush or break the tablets, always swallow whole
  • Should be taken with food
  • If you miss a dose, take it as soon as you remember
  • Never double the dosage to make up for the missed tablet
  • If you miss a dose, skip it and carry on treatment as normal
  • Never discontinue treatment without first consulting your doctor
Page last reviewed:  17/09/2020
Please read the patient information leaflet for this medicine fully before use:

Venlalic XL 75mg

Venlalic XL 37.5mg

Venlalic XL 150mg

Venlalic XL 225mg

Side effects & warnings

Side effects

All medications are capable of producing side effects, so it is important to understand what these are as well as any other risks involved. In rare circumstances, side effects can be serious, including severe allergic reactions. If you experience any of the following, seek immediate medical assistance:

Seizures, significantly increased heartbeat, suicidal thoughts, compulsion for self-harm, pain in joints, swollen mouth, lips and tongue, profuse sweating, high temperature, jaundice or liver failure, problems breathing, inability to swallow, rashes and hives, tightness in the chest, loss of coordination, hallucinations, altered blood pressure, vomiting, chills, shivering, flu-like symptoms. 

Very common (more than 1 in 10 users)

Headaches, dry mouth, nausea, constipation, dizziness, sweating.

Dry mouth affects around 10% of those using Venlalic. A constant dry mouth can lead to dental hygiene issues, so it is important to take extra care in maintaining your oral health. 

Common (up to 1 in 10 users)

Weight gain, weight loss, inability to orgasm, sense of detachment, tremors, decreased libido, dilated pupils, blurred vision, changes in the sense of taste, tinnitus, lowered appetite, nightmares, heightened blood pressure, chills, tiredness, confusion, palpitations, excess yawning, problems passing urine, impotence, irregular menstruation, high cholesterol, mild rash, restlessness, pins and needles, shortness of breath, diarrhoea.

Uncommon (up to 1 in 100 users)

Hallucinations, unemotional detachment, overexcitement, black tarry stools, dizziness when standing, blood in stools, hair loss, vomiting blood, decrease in blood pressure, muscle jerks, altered orgasm, teeth grinding, sunlight sensitivity, incontinence, lowered liver enzymes.

Rare (up to 1 in 1,000 users)

Seizures, coughing, wheezing, dark urine, flu-like symptoms, inflammation of the liver, yellow eyes or skin, irregular heartbeat, confusion coupled with hallucinations, fainting, excessive water intake (also known as SIADH, Syndrome of Inappropriate Antidiuretic Hormone Secretion).

Very rare (up to 1 in 10,000 users)

An inability to stop bleeding (a sign of reduced platelets in the blood), increased bruising, blood in urine and vomit, abnormal production of breast milk, broken veins.

Unknown frequency

Suicidal thoughts or behaviours.

Warnings

Conditions to look out for

There are two types of reactions that a doctor will need to consider before writing a prescription for Venlalic: those that might cause interactions issues, such as increasing the likelihood of side effects; and those that mean Venlalic must be avoided. It is therefore essential that you inform your prescribing clinician of any conditions that you suffer from now or that you may have experienced in the past.

Those with the following conditions should avoid using Venlalic:

An allergy to one or more of the ingredients in Venlalic.

The following conditions may make use of Venlalic inappropriate or the treatment may have to be adjusted:

Diabetes, glaucoma, heart problems, a history of fits or seizures, hyponatraemia (low blood sodium levels), bruising easily and deeply, bleeding easily (haemophilia), a family or personal history of bi-polar or mania, a tendency for aggression.

Taking it with other medications

All drugs have the potential to interact with others, with some negating or enhancing the effects of other types of medication. Some side effects can be hazardous, so you need to inform your prescribing clinician of any medications that you are currently taking or have recently taken. This includes any herbal medicines.

The following medication must be avoided when taking Venlalic:

MAOI antidepressants, medications containing Venlafaxine, blood thinners.

The following medications may make Venlalic unsuitable for you:

Triptans (migraine medication), St John’s Wort, antipsychotics, opioid painkillers (such as tramadol, fentanyl, tapentadol, pethidine), methadone, antibiotics containing linezolid, weight loss medication containing sibutramine, medications containing methylene blue, medications that may affect the heart (such as antiarrhythmics, the antibiotics erythromycin and moxifloxacin, antihistamines, ketoconazole, metoprolol, haloperidol, risperidone.

Pregnancy and breastfeeding

If you are pregnant, think you might be pregnant or are planning to be pregnant in the near future, you should inform your doctor before starting using Venlalic as another treatment might be more appropriate. Venlalic has been found, in a small number of cases, to cause some issues for newborn babies, especially if taken towards the end of pregnancy. These issues include PPHN, persistent pulmonary hypertension, whereby the baby finds it difficult to breathe and appears flush, which begins within the first 24 hours of the birth. There is also a chance that the baby will not feed properly and have floppy limbs.

Breastfeeding is also not appropriate while using Venlalic as trace amounts of the drug are found in breastmilk.

Driving and machinery

You should be aware that you may not be able to drive while using Venlalic as you may experience dizziness and an inability to focus, although such symptoms do tend to subside over the course of a few weeks.

Food, drink and alcohol

Venlalic should not be taken on an empty stomach. Many find that some of the side effects, particularly nausea, are reduced when taken after breakfast. It should be swallowed whole with water. It is recommended that you avoid consuming alcohol while taking Venlalic.

Fertility

There is no evidence that suggests that Venlalic has any effect on fertility for men or women.

Page last reviewed:  17/09/2020
Please read the patient information leaflet for this medicine fully before use:

Venlalic XL 75mg

Venlalic XL 37.5mg

Venlalic XL 150mg

Venlalic XL 225mg

Q&A

How should I store it?

Venlalic requires no special instructions for storage, other than to keep it out of reach of children and in an environment that does not exceed 30°C.

Can I drink alcohol?

Antidepressants can interact with alcohol, increasing the likelihood of side effects. As alcohol is also a depressant, it may also make your symptoms worse if you suffer from depression or anxiety. For these reasons, it is best to avoid consuming alcohol while using Venlalic. 

Can I buy Venlalic over the counter?

It is not possible to get over the counter, so you will need a prescription to buy Venlalic online or from your local pharmacy. 

How do I buy Venlalic online?

You should always seek a face to face consultation with your doctor at the beginning of treatment.

In order to buy Venlalic online you will need to obtain a prescription. We are able to provide a prescription through our GMC registered doctors only if you have already been prescribed Venlalic. This can then be sent to our UK based pharmacy, which is registered by the GPhC, and then sent to you by next day courier, discreetly.

Our video consultations can also provide you with advice, fit notes and access to the relevant specialists if other treatment is deemed more appropriate. It is available from 9am until 5pm, Monday to Friday.

Page last reviewed:  17/09/2020
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