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Migraines are very painful, intense headaches, often accompanied by other symptoms such as visual problems, nausea or vomiting.

  1. Caused by inflamed blood vessels
  2. Can last for several days in some cases 
  3. Effective, rapid relief is available

Not everyone has time to pick up their migraine prescription in person. Our online service enables you to get the treatment you need from a trusted UK seller, delivered to your home.

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0 product result(s) for Migraines



  1. Relief from symptoms
  2. Comes in two strengths
  3. Licensed generic treatment
Zolmitriptan Orodispersible

Zolmitriptan Orodispersible

  1. Dissolve in the mouth
  2. Migraine relief
  3. Alleviates sickness and other symptoms
Maxalt Melt

Maxalt Melt

  1. Melt in the mouth tablets or wafers
  2. No water required to take them
  3. Relieves migraine symptoms


  1. Effective drug for migraine
  2. Nasal spray or tablet available
  3. Branded GSK medication
Zomig Nasal Spray

Zomig Nasal Spray

  1. Easy to apply spray
  2. Migrane relief
  3. Made by an established brand


  1. Effective tryptamine-based treatment
  2. Migraine relief
  3. Easy to swallow, film coated tablets


Migraines are particularly severe headaches, which can often be so painful that they may affect your judgment, or impede movement. When a migraine is underway, it can be very difficult in some cases for the person experiencing it to perform basic tasks. Around six to eight per cent of males get them, but they are even more common in women. It is thought that they affect as many as 20 per cent of women in the UK.

Many cases of migraine (but not all) will be preceded by something called ‘aura’.

The symptoms of aura include seeing flashing, zig-zag lines or black patches, a heightened sensitivity to noise and light, and altered sensations, such as numbness, in one hand, which may travel up the arm and to the face. These usually occur before a migraine headache begins, and are referred to by some as ‘warning signs’.

Some people may experience no aura beforehand; whereas others may get symptoms of aura, but no headache. This is called silent migraine.

Why the condition occurs in some people and not others isn’t fully understood. However, experts posit that you are more likely to experience migraines if you have a family history of them. Symptoms tend to come about in response to a trigger, which can vary from one individual to another.

These can be emotional, physical, dietary or environmental in nature. For instance, feelings of stress might act as a trigger, as might a lack of sleep, or a missed meal. Some people get attacks following the consumption of alcohol or caffeine, or after being in a stuffy environment for too long.

At present, there is no cure for migraines. Those who get them are likely to experience recurrent episodes, particularly if they are susceptible to triggers which are difficult to avoid.

Treatment aims at reducing the severity of migraines; and for some, over-the-counter painkillers are a sufficient means of doing this. However, many people may find that this type of medication does not alleviate symptoms, and require more specialised treatment.

Prescription drugs for migraines are available in the form of tryptamine-based drugs, also known as triptans. As well as easing the effects of a painful headache, they can help to curb associated symptoms such as feelings of sickness, and reduce visual disturbances and hearing problems.

In the brain, various activities involving chemical reactions and neurotransmitters are taking place all the time. For people with migraines, these activities can lead to the inflammation and widening of blood vessels around the brain. This then results in pain, often one side of the head. Triptans mimic the function of serotonin in the brain, by working on certain receptors. In doing this, they help to narrow the offending blood vessels, and lessen symptoms.

The migraine products available to buy online from our UK-based pharmacy include Zolmitriptan, Imigran Nasal Spray, Zomig Nasal Spray and Sumatriptan.

If you are experiencing migraines for the first time, or have never taken treatment before, we recommend that you see your GP in person.

If you’re looking to get your regular migraine medication online, our service provides a quick and easy means of doing so. Just fill in our short questionnaire, and one of our GMC-registered practitioners will study your responses. If your chosen medication is safe for you, they will draw up a prescription and issue this to our trusted pharmacy. Your order will be then be dispensed and shipped via overnight courier.

Page last reviewed:  26/04/2022
Types of Treatment

Types of Treatment

In milder cases, over-the-counter relief such as ibuprofen or paracetamol can produce positive results in reducing symptoms. However, these non-prescription solutions do not always suffice, and many people will require a more targeted course of treatment. This is more typically issued in the form of triptans, such as Sumatriptan, Imigran Nasal Spray, Zomig Nasal Spray or Zolmitriptan Orodispersible tablets.

How do they work?

Migraines are the result of certain chemical reactions in the brain, which cause surrounding blood vessels to become inflamed and dilate. Triptans, or tryptamine-based medicines, work by stimulating certain receptors in the brain, and facilitating the reversal of this dilation. This causes the blood vessels to contract and eases symptoms.

What are the side effects?

The more common side effects of triptans include dry mouth, altered sense of taste, and drowsiness. Refer to the relevant product page for more detailed information.

Can I take them with other medications?

This kind of treatment may not be safe to take in conjunction with certain products, such as other migraine drugs, antidepressants, or certain antibiotics. Make sure you inform your prescriber if you are taking these or any other non-prescription, non-prescription or remedial products before use.

Page last reviewed:  26/04/2022
Question and Answers

What’s the difference between the medications?

All the treatments we offer for migraine are designed to be taken when an attack is beginning or in progress. They are not to be used as preventative drugs.

The products mainly differ in their mode of application, and their content: Sumatriptan is a tablet taken orally with water; Zolmitriptan is an orodispersible tablet which dissolves in the mouth; whereas Zomig (branded Zolmitriptan) and Imigran (a brand of Sumatriptan) are both issued as nasal solutions. These are both supplied in a pre-loaded applicator and sprayed into one nostril.

Should I take Sumatriptan, Zolmitriptan, Imigran Nasal Spray or Zomig Nasal Spray?

It really depends on what your GP has recommended, as well as your preferred method of administration. Tablets work well, but nasal sprays and orodispersible tablets tend to have a faster onset of action.

If you haven’t used migraine treatment before, we advise that you see your GP in person.

Are there different side effects?

The more common side effects are mostly concurrent across each of these products, and include drowsiness, flushing, or tenderness in the fingers and toes. However, there may be small variations according to the delivery method you choose. For instance, the nasal spray may cause side effects which the tablets do not, and so on. You can find out more by referring to the respective product pages.

Is it right for me?

If you aren’t sure which treatment is most suitable for you, or if you haven’t taken medication before, speak to your GP for advice.

If you are looking to buy your regular migraine medication online, complete one of our confidential online questionnaires today, and your answers will be analysed by one of our practising medical advisors. They will only approve a treatment if they believe it is safe. Once your order has been confirmed and dispensed by our UK-based pharmacy, our courier partners will ship it to you via tracked parcel.

Page last reviewed:  26/04/2022

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We promise to keep your details secure and private. We will never sell your information or share it with third parties. Whatever treatment you buy online from us, we will send in plain, unmarked packaging via our secure courier service.

Delivery on all items is included in the price. After your order has been dispatched, you’ll be supplied with a tracking number, allowing you to follow the progress of your items every step of the way. We deliver to anywhere in the UK, so whether you’re in London, Birmingham, Manchester, Glasgow or Cardiff, your order will be at your door within just 24 hours of approval from our doctor.

This content was reviewed by a clinician on

26 April 2022
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 26 April 2022
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