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Zomig Nasal Spray


Zomig Nasal Spray is a migraine relief drug, manufactured by Grunenthal. It soothes pain and eases other migraine-associated symptoms.

It can be tough getting to your local chemist when a migraine takes hold. Now you can have the effective treatment you need delivered to your door. Take our medical questionnaire today, and we’ll do the rest.

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PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.

This content was reviewed by a clinician on

26 April 2022
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 26 April 2022
Product information

Zomig Nasal Spray is a medication made by Grunenthal, used in migraines. In addition to relieving headache pain which migraines often cause, it can also help to reduce feelings of sickness and visual problems. Taken during the onset of symptoms, it provides a viable alternative for those who prefer not to use tablets, and gets to work immediately.

Estimates suggest that as many as one in five women and one in fifteen men in the UK experience migraines. Why some people get them and others do not isn’t fully understood, although many doctors speculate that genes are a contributing factor. Some people think that a migraine attack is just a really bad headache, when in actual fact they can be much more debilitating.

Migraines fall into three main categories: migraine with aura; without aura; and silent migraine. Those who experience aura will usually get warning signs before their headache takes hold. Sight problems, hearing problems and feelings of sickness are common characteristics in these cases. People who have migraines without aura will usually bypass these symptoms, and the first thing they’ll notice is an intense throbbing head pain. Silent cases are those where a person displays signs of aura, but does not get a headache.

The aim of treatment is to alleviate pain and limit the severity of other symptoms. Some may find that over-the-counter painkillers help; but others may require more specific solutions, geared particularly to the medication of migraines.

Zolmitriptan, which is the working ingredient in Zomig Nasal Spray, is an example of a triptan, or tryptamine-based drug. It is a 5HT agonist, which means that it works on serotonin receptors in the brain. A migraine occurs when blood vessels around the brain swell, and exert pressure. The action of zolmitriptan causes these blood vessels to narrow, and this helps to soothe pressure and relieve symptoms.

We know that getting access to fast and effective relief is essential. Our UK-based pharmacy can ship Zomig Nasal Spray to your home via overnight courier. All you need to do is take our simple medical assessment. Your order will be processed and dispensed as soon as our doctor has checked your answers and approved your items.

Page last reviewed:  26/04/2022


To get the most out of your medication, it is essential to follow the guidelines provided by your doctor, and adhere to the instructions supplied in the information leaflet. Doing so will also help to keep the risk of side effects to a minimum.

  1. Administer as prescribed.
  2. Typically, this will be one sprayed dose of 5mg when you feel migraine symptoms beginning.
  3. Please note that this drug should not be used to prevent migraines. It is only intended for the treatment of those which are already underway.
  4. Using the nasal dispenser, spray the solution into one nostril.
  5. For detailed instructions on how to use the dispenser, refer to the leaflet provided.
  6. Only one dose is used per attack. You may only take another spray if your migraine comes back and you have not used the product for a period of at least two hours.
  7. Do not exceed two doses in any one day.
  8. If your symptoms do not go away after using this product, consult your doctor.

These directions are intended only as a guide, and do not comprise detailed instructions. Familiarise yourself with the patient information leaflet fully prior to use.

Download Zomig Nasal Spray patient information leaflet

Page last reviewed:  26/04/2022
Please read the patient information leaflet for this medicine fully before use:

Zomig Nasal Spray 5mg

Side effects & Warnings

Side effects

Not everyone who uses this product will get side effects. Nevertheless, it is important to be aware of the responses this drug may cause, as some, such as the following, may require immediate medical attention: allergic reactions which may be indicated by a rash, or facial or oral swelling; chest pain or shortness of breath, as these may be signs of heart problems; stomach pain and bloody diarrhoea; bleeding in the brain; or stroke.

Common (1 in 10 people or less):
Tingling or similar sensations in the fingers and toes, drowsiness, headache, irregular heartbeat, nosebleed, feeling or being sick, stomach pain, dry mouth, muscle weakness pain, or difficulty swallowing.

Uncommon (1 in 100 people or less):
Increased heartbeat, rise in blood pressure, or more frequent urination.

This is not a complete account of the side effects which this drug may induce. Refer to the patient information leaflet for more.

Taking it with other medicines

It is important to disclose any information relating to the use of other treatments when completing our medical assessment. The following products may cause Zomig to work differently, or vice versa: other triptans; ergotamines or derivatives such as dihydroergotamine or methysergide; St John’s wort; MAOIs such as moclobemide; SSRIs including fluoxetine, paroxetine, fluvoxamine and sertraline; SNRIs, for instance venlafaxine or duloxetine; cimetidine; or quinolone antibiotics such as ciprofloxacin.

Conditions to look out for

Your prescriber needs to be informed of any conditions you have which may make this item unsuitable. Do not use this drug if you have: high blood pressure; a history of heart problems or angina; or ever had a stroke or transient ischaemic attack. You may be advised to take special care when using this treatment if you: are at risk of getting ischaemic heart disease; smoke; have high levels of cholesterol; have diabetes; have Wolff-Parkinson-White Syndrome; or have liver problems.

Pregnancy and breastfeeding

Talk to your GP before using this treatment if you are pregnant, breastfeeding or trying for a baby.

Driving and using machinery

Your driving skills and capacity to use machines may be inhibited by migraine symptoms. Do not drive or use machinery if you are affected by these.

Page last reviewed:  26/04/2022
Please read the patient information leaflet for this medicine fully before use:

Zomig Nasal Spray 5mg


Can I still drink alcohol?

Alcohol may make migraine symptoms worse, so we would advise against drinking alcohol when using this product.

Will I still be able to drive?

If you are experiencing a migraine attack or taking treatment for one, driving is not recommended.

Can I use this medicine while pregnant?

You should only use this item during pregnancy if you doctor thinks you absolutely need to. It may not be suitable for use during breastfeeding.

How do I store it?

Store it in a safe environment below 25°C.

Am I allergic to anything in the medicine?

This product contains zolmitriptan, citric acid, disodium phosphate and purified water. Do not use it if you are allergic to or unable to tolerate any of these components.

Is it available over-the-counter?

You will need a prescription to be able to buy Zomig Nasal Spray in the UK.

Is it right for me?

Your GP will discuss treatment options with you if you have never used migraine treatment before, or if you have developed new symptoms or are getting migraines for the first time. Make an appointment to see them if this applies to you.

Our GMC-registered doctors can help you get the repeat treatment you need. It takes no more than a few minutes to fill in our health assessment. Once complete, your answers will be reviewed by a qualified physician, who will only approve your treatment if it is safe to do so. Every item our UK-based pharmacy dispenses is dispatched by overnight courier.

Page last reviewed:  26/04/2022
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