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Locoid Scalp Lotion

Hydrocortisone bulyrate

Locoid Scalp Lotion is a treatment for psoriasis. It is applied to the scalp to reduce inflammation.

Please note that we do not provide psoriasis treatment through our service at this time.

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PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.

This content was reviewed by a clinician on

30 August 2020
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 30 August 2020
Product information

Locoid Scalp Lotion is a treatment made by Astellas, and is used for psoriasis of the scalp. It contains an agent called a corticosteroid, which helps to reduce the activity of inflammatory chemicals in the body, which result in irritation and symptoms. To buy Locoid Scalp Lotion you will need a prescription.

  1. Corticosteroid solution
  2. Simple to use
  3. Fights symptoms

Psoriasis is a condition which affects the skin. Roughly two percent of the UK population are thought to have the condition in some form. It is chronic in nature, usually passing through periods of activity and dormancy. Most people will develop their first outbreak prior to the age of 35, although it can occur for the first time at any age.

Typical symptoms include redness, irritation, itchiness and the development of scaly skin flakes. These can develop just about anywhere on the body, but are more likely to occur on the elbows and knees, the lower back, and on the scalp. Despite the condition not posing a serious threat to health, psoriasis can be frustrating to endure.

It isn’t fully understood why some people have the condition and others do not, but the immune system is thought to be at the root of flare-ups. Sometimes, the body’s defences perceive a threat when there is none present, and release inflammatory chemicals to alert the person to the injury or illness. This, where the immune system essentially attacks the body, is known as an autoimmune condition.

In psoriasis, these inflammatory chemicals cause redness and irritation of the skin, and the generation of new skin cells before old ones are ready to be shed. This results in flaking.

Several triggers have been identified by people with psoriasis as instigators of a flare-up. These range from a reaction to medication, hormonal changes taking place in the body, stress, excessive alcohol consumption, smoking, or skin injuries. Avoiding these potential triggers can help to limit the likelihood of an episode, however, in cases where symptoms are present to a moderate or severe degree, a doctor may suggest the use of a topical corticosteroid to lessen discomfort and expedite the healing process.

Hydrocortisone butyrate, the active ingredient in Locoid Scalp Lotions, works by inhibiting the action of chemicals released by the immune system which cause inflammation.

This medicine is not available through our service. If you are not already using this product under the instruction of your GP or specialist, or if you have not seen a healthcare professional before about your symptoms, you should make an appointment with your doctor in person.

This is so that they can help you identify the most suitable form of treatment.

Page last reviewed:  30/08/2020


It is crucial to follow the directions your prescriber gives to you, and to read the guidelines in the patient information leaflet carefully beforehand. This will help the treatment to be as efficient as possible and also help you to lower the risk of side effects.

  1. Use as directed.
  2. This will typically be a thin layer applied and gently rubbed into the scalp, no more than twice daily.
  3. Only use it on the scalp.
  4. Consult your doctor if your symptoms do not improve.
  5. Never exceed the prescribed dose.
  6. If you forget to use it, skip the dose you have missed and carry on the treatment as normal.

For a more detailed list of instructions, please refer to the leaflet provided.

Download PDF


Page last reviewed:  30/08/2020
Please read the patient information leaflet for this medicine fully before use:

Locoid Scalp Lotion 0.1%

Side effects & Warnings

Side effects

If you notice anything resembling an allergic reaction to this treatment, or worsening of psoriasis symptoms, you should speak to your doctor as soon as possible.

Rare (1 in 1,000 patients or less):
Thinning of the skin, redness of the skin, bruising and stretch marks, facial spots, redness of the skin around the mouth, worsening of the skin condition after treatment has stopped, or discolouration of skin.

Very rare (1 in 10,000 patients or less):
Suppression of the release of the stress hormones.

For more comprehensive information on side effects, refer to the leaflet supplied with the medicine.

Taking it with other medicines

Let your prescriber know about any other treatments you are using at time of consultation.

Conditions to look out for

This item should not be used to treat facial skin, the genitals, your eyes or your eyelids. It is intended for scalp use only.

It should also not be used for long periods on psoriasis outbreaks, as it may cause the condition to worsen upon ceasing treatment in such cases.

Pregnancy and breastfeeding

Do not use Locoid if you are pregnant, breastfeeding or trying to conceive unless your doctor thinks it is absolutely necessary. Speak to your GP for further advice before use.

Driving and using machinery

This product is not likely to inhibit your capacity to drive or use machines.

Page last reviewed:  30/08/2020
Please read the patient information leaflet for this medicine fully before use:

Locoid Scalp Lotion 0.1%


Can I still drink alcohol?

Yes. It is not thought that alcohol will reduce the efficacy of this lotion.

Will I still be able to drive?

Yes. Your capacity to drive is unlikely to be inhibited. If you feel as though it has been, however, do not drive and contact your doctor as a point of urgency.

Can I take the medicine while pregnant?

It should not be used by those who are pregnant or breastfeeding unless absolutely necessary. Talk to your doctor beforehand in either case.

How should I store it?

In a safe environment below 25°C, and out of the reach of children.

Am I allergic to anything in the medicine?

Contained in this product are the following ingredients: hydrocortisone butyrate, isopropyl alcohol, glycerol, povidone, citric acid, sodium citrate and purified water.

If you are allergic to any of the above, do not use it.

Is it available over-the-counter?

You will need a prescription in order to be able to buy Locoid Scalp Lotion from any UK-based pharmacy. This needs to be issued a by a clinician or healthcare professional.

Is it right for me?

If you have not used this item before, you should speak to your GP in person. They will assess your symptoms and issue a prescription for the most appropriate treatment.

Please note that we do not offer this medication through our online service.

Page last reviewed:  30/08/2020 is rated 4.9 out of 5 by 3131 customers on TrustPilot!
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