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Alcometasone DiPropionate

Modrasone is a topical cream used to treat skin conditions, such as psoriasis. It is a type of medicine called a corticosteroid.

We recommend you speak to your doctor if you are seeking psoriasis treatment.

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PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.

This content was reviewed by a clinician on

24 July 2020
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 24 July 2020
Product information

Modrasone is a type of cream treatment used in skin conditions. It is applied to the skin two or three times per day, and helps to reduce inflammation related to dermatitic conditions like psoriasis. Available to buy only on prescription, Modrasone is marketed in the UK by Merck Sharp and Dohme.

  1. Simple to apply cream
  2. Two or three a day dose
  3. Effective at tackling skin irritation

Psoriasis is an inflammatory skin condition which causes a range of symptoms, including itching, and flaky, scaly patches on the skin. These may also be red, and more prone to breaks; leading in turn to bleeding. In rarer cases, pustules may also form, particularly if the affected area becomes infected during a flare-up.

The condition is a chronic one, and will go through periods of activity and dormancy. It will usually appear in someone who has it before they reach the age of 35, but it can appear later than this. It is still unclear why the condition occurs or what causes it, but it is thought to be an autoimmune problem. Someone who has psoriasis will generally produce skin cells at a faster rate than someone who doesn’t, leading to excess skin cells which flake off and cause irritation when they rise to the surface.

Several triggers are thought to be contributing factors in a flare-up, but these will tend to vary from person to person. More common triggers include smoking, stress, the excessive consumption of alcohol, a change in hormone levels, or a skin injury. The condition can also be initiated by medication. The most common areas affected by psoriasis are the elbows and knees, the scalp and the lower back.

When treating the condition, a doctor will first assess the severity of symptoms present before deciding on a course of action. In cases where symptoms are mild to moderate, they may issue a topical cream such as Modrasone to help get a reactivation under control. The functioning constituent in this topical cream is a substance called alclometasone dipropionate, which is a corticosteroid. Medicines such as this one work by inhibiting the activity of a chemical released by the immune system, which can induce inflammation in the area affected and cause symptoms.

If you have not used treatment before or have not seen a doctor to have your symptoms examined in person, we recommend you see your own GP.

We do not provide this medication through our service. Please refer to your GP if you are seeking treatment or looking to renew your prescription.

Page last reviewed:  24/07/2020

It is important to follow the directions issued by your prescriber when using this treatment, and also to read the guidelines in the patient information leaflet carefully. This will not only help you to get the best possible results from the product, but will also help you in reducing the likelihood of side effects.

  1. Use as directed.
  2. This will usually be one thin application to the affected region, two or three times per day.
  3. Once applied, gently massage the cream into the skin.
  4. It is not suitable for use over long periods.
  5. Never exceed the amount prescribed for you.
  6. In the event that you forget to use it, apply it as soon as you remember, before carrying on the course as normal.

These directions are intended only as a guide. For more detailed instructions, please consult the leaflet supplied.

Download PDF

Page last reviewed:  24/07/2020
Please read the patient information leaflet for this medicine fully before use:

Modrasone 0.05%

Side effects & Warnings

It is important to be aware of the potential side effects associated with this product, so that you can take the appropriate action in the event that they occur. Any signs of an allergic reaction should be reported to your doctor as soon as possible.

Other side effects (frequency not stated):
Thinning of the skin, stinging, blistering, peeling, swelling, itching, burning, skin rash, dryness, red marks, inflammation of the hair follicles, excessive hair growth, and reduced skin pigmentation.

This is not a complete list of the side effects associated with this product. A more detailed account can be located in the leaflet supplied.

Taking it with other medicines

Let your doctor know during consultation if you are using any other treatments.

Conditions to look out for

It may make some skin conditions worse. Those who have any of the following should notify their doctor, as they may choose to issue an alternative treatment: rosacea, acne, dermatitis around the mouth, cold sores, chickenpox, or skin infections, be they bacterial, fungal or viral.

Pregnancy and breastfeeding

If you are pregnant, planning to become pregnant or breastfeeding, talk to your doctor before using this treatment.

Page last reviewed:  24/07/2020
Please read the patient information leaflet for this medicine fully before use:

Modrasone 0.05%


Can I still drink alcohol?

Yes. Alcohol is not likely to affect how this cream works.

Will I still be able to drive?

Yes. It is unlikely that your driving ability will be compromised.

Can I take the medicine while pregnant?

It may not be suitable. Speak to your doctor prior to using this treatment if you are pregnant or breastfeeding.

How should I store it?

In a safe place place, below 25°C, and out of the reach of children.

Am I allergic to anything in the medicine?

This medication contains the following ingredients: alclometasone dipropionate, propylene glycol, white soft paraffin, cetostearyl alcohol, glyceryl stearate PEG 100 stearate, polyoxyethylene (20) cetyl ether, sodium dihydrogen phosphate dihydrate, 4-chloro-M-cresol, phosphoric acid and purified water.

Do not use it if you are allergic to any of these constituents.

Is it available over-the-counter?

You can only buy Modrasone in the UK if you have a prescription for it.

Is it right for me?

Psoriasis treatment must be initiated following a face-to-face consultation. Make an appointment with your GP if you think you have symptoms but have not received a specific diagnosis or used treatment before.

Please note that we do not offer this treatment through our online service.

Page last reviewed:  24/07/2020 is rated 4.9 out of 5 by 3131 customers on TrustPilot!
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