Mirapexin

  • Pramipexole

Mirapexin tablets are used to treat restless legs syndrome. They contain the active ingredient pramipexole which is a type of medicine called a dopamine agonist.

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0.18mg

There are 0.18mg of pramipexole in this dose.

0.088mg

This tablet contains 0.088mg of the active ingredient pramipexole. During the first week one tablet is taken once a day. This dose may be increased intermittently until a maintenance dose is reached.

30 Tablets - £58.00
0.35mg

This dose contains 0.35mg of the active ingredient pramipexole.

0.7mg

Mirapexin 0.7mg contains 0.7mg of pramipexole.

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Mirapexin is a treatment manufactured by Boehringer Ingelheim and is used to combat Restless Legs Syndrome (RLS). The tablets contain the active ingredient pramipexole and fall into the group of medicines known as dopamine agonists. When initially prescribed the medicine is usually commenced on a low dose which is gradually increased to a maintenance dose.

  1. Effective treatment for restless legs syndrome
  2. Usually taken once a day
  3. Available in tablet form

Restless legs syndrome is not uncommon and it is thought that one in ten people develop the condition at some point during their lives. It can affect anyone at any age but is twice as common in women. RLS can be linked to an underlying health problem such as iron deficiency anaemia and kidney failure. However, for many people living with RLS there is no obvious cause.

The condition can sometimes run in families. One in five pregnant women go on to notice symptoms during the last three months of their pregnancy, again there is no clear reason as to why. Most cases of pregnancy induced RLS resolve after birth.

Whilst RLS is not a life threatening condition if left untreated it can worsen and potentially be disruptive. Living with restless legs can impact your quality of sleep, and this can in turn have an effect on quality of life.

If you have a mild case of restless legs syndrome you might firstly be advised to look at your lifestyle habits and see if there are improvements to be made. This might include quitting smoking if you smoke, introducing better sleeping habits and getting regular exercise during the day. Those whose RLS is linked to another health condition should take steps to receive treatment for that condition; as in many cases this can resolve RLS symptoms. There are certain techniques that can be adopted to relieve a restless legs episode. Your doctor might advise you to massage your legs, go for a walk, use a hot or cold compress on the area, try yoga or tai chi and distract yourself with other activities.

For more severe cases of RLS there are treatments available in the forms of dopamine agonists, such as Mirapexin. This drug contains the active substance pramipexole which stimulates dopamine receptor sites in the brain. Doing so restores the dopamine signalling levels in the brain which is subsequently thought to reduce restless legs symptoms. If you commence Mirapexin treatment and your condition does not improve then you should consult with your doctor on the best course of action.

Please note this treatment is not available to buy through our site.

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How to use Mirapexin

When using this medication always follow the directions provided by your doctor, and adhere to the guidelines set out by the patient leaflet. Doing so will help you get the best possible results from the drug and also reduce the likelihood of side effects.

  1. Take the tablets as directed.
  2. Normally, this will be once a day, in the evening, around 2-3 hours prior to going to bed.
  3. Mirapexin users usually start on the lowest dose for one week before increasing the dose the next week. The increments take place as directed by your doctor in order to achieve a dosage which manages your symptoms.
  4. The dose should not exceed more than six tablets of 0.088 milligrams or 0.54 milligrams.
  5. If you want to stop taking your medication for more than a couple of days, you should bear in mind that when you recommence treatment you will need to start at the lowest dose and build up again.

Full details can be found in the leaflet provided with the product.

Download PDF

Mirapexin side effects

All medicines have the potential to cause side effects and Mirapexin is no different. This does not necessarily mean that you are guaranteed to experience any side effects but you should be aware of them.

Very common (1 in 10 people or more):

Nausea.

Common (1 in 10 people or less):

Sleep disturbance, fatigue, unusual dreams, headaches, constipation, dizziness and vomiting.

Uncommon (1 in 100 people or less):

Dyskinesia, hyperkinesia, compulsive behavioururge to behave differently, amnesia, delusion, paranoia, hallucinations, confusion, sleepiness, cardiac failure, changes in antidiuretic hormone secretion, weight increase, hypotension, peripheral oedema, allergic reaction, fainting, restlessness, weight loss, visual impairment, hiccups, pneumonia, dyspnoea, mania, delirium and an uncontrollable urge to perform an action which could be harmful to you or others.

Taking it with other medicines

Please let your doctor know if you are taking any other treatments when completing our medical consultation. This product may not be suitable for use in conjunction with: cimetidine, amantadine, mexiletine, zidovudine, cisplatin, quinine, procainamide, levodopa and any antipsychotic medications.

Conditions to look out for

It is crucial for our doctor to know about any medical conditions you currently have or have had in the past. Particular attention should be paid to the following: kidney disease, hallucinations, episodes of suddenly falling asleep, dyskinesia, psychosis, vision impairment, heart or blood vessel disease and augmentation.

Pregnancy and breastfeeding

Check with your doctor before taking Mirapexin if you are pregnant or trying to become pregnant.

This medication should not be used during breastfeeding.

Driving and using machinery

If you have any side effects which could affect your concentration or vision, do not drive or use machines, and tell your doctor.

Food, drink and alcohol

If you are taking this treatment, you should exercise strict caution when consuming alcohol.

Q&A: our Mirapexin discussion forum

Can I still drink alcohol?

Caution is advised when taking Mirapexin and drinking alcohol.

Will I still be able to drive?

This depends on how your body reacts to the medication. If you experience hallucinations or sleepiness you should not drive or operate machinery.

Can I take the medicine while pregnant?

You will need to have a discussion with your doctor prior to commencing Mirapexin treatment if you are pregnant, are planning a pregnancy or are breastfeeding.

How should I store it?

Store in the original packaging, under 30°C and out of the reach and sight of children.

Am I allergic to anything in the medicine?

Do not commence Mirapexin treatment if you have an allergy to any of the following ingredients: pramipexole, pramipexole dihydrochloride monohydrate, mannitol, maize starch, anhydrous colloidal silica, povidone K 25 and magnesium stearate.

Is it available over-the-counter?

In order to purchase Mirapexin tablets you will need a prescription.

Is it right for me?

Talk to your doctor if you think you may have restless legs symptoms. They will be able to assess your condition and issue a treatment where required.

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