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Gonorrhoea Treatment


The Gonorrhoea treatment contains two antibiotic medications, Azithromycin and Suprax.

We offer simple-to-use home test kits for gonorrhoea, that can provide a result in as little as 15 minutes. If you have tested positive for gonorrhoea and are not able to receive the first-line treatment, you can buy gonorrhoea treatment online using our confidential service.

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Azithromycin, Suprax500mg/200mg

Take as prescribed. The typical dose for the treatment of gonorrhoea infections is 2000mg of Azithromycin (4 tablets) and 400mg of Suprax (2 tablets) as a one-time dose.

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You can highlight a preferred treatment, dose or amount to our prescriber, but to ensure your safety the final decision on any treatment you are offered is always the prescriber's. After your consultation, our prescriber may suggest a different treatment, or dose or amount of treatment (or not recommend treatment at all).

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The Gonorrhoea treatment contains two antibiotic medications, Azithromycin and Suprax.

We offer simple-to-use home test kits for gonorrhoea, that can provide a result in as little as 15 minutes. If you have tested positive for gonorrhoea and are not able to receive the first-line treatment, you can buy gonorrhoea treatment online using our confidential service.

This content was reviewed by a clinician on

11 March 2021
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 11 March 2021
Product information

This gonorrhoea treatment contains two medicines: Azithromycin and Suprax. These are taken as a one-off dose for the medication of gonorrhoea. Symptoms of infection will then usually begin to clear up in a matter of days.

Although they are both antibiotic medicines, they function in slightly different ways. They are much less effective when used on their own, which is why it is important to buy Azithromycin and Suprax together.

Please note that this treatment is not the first line medicine for gonorrhoea. The preferred treatment for gonorrhoea is azithromycin given in combination with an injection, which has to be administered by a healthcare professional in clinic.

The antibiotics in this pack are slightly less effective against resistant strains of gonorrhoea than the first line treatment. So, you should only use this treatment if you are unable to have the injection.

BASHH guidelines published in 2011 for this type of treatment, when used as a second line option in gonorrhoea, advise a 1g dose of Azithromycin (in addition to Cefixime or Suprax). However, we advise taking 2g of Azithromycin in line with European guidelines on gonorrhoea treatment which were published more recently, in 2012.

Colloquially referred to as ‘the clap’, gonorrhoea is one of the most common sexually transmitted infections in the UK, with around 25-30,000 cases being reported at NHS GUM clinics on an annual basis. It is a bacterial infection found in semen and vaginal fluid, and is therefore spread through unprotected forms of vaginal, anal or oral sex. The shared use of sex toys is a possible method of transmission too. It can also be passed down from mother to child if present during pregnancy.

The condition can often be asymptomatic; one in ten male cases and as many as half of all female cases will notice no visible signs of infection. However, those who do experience symptoms may notice a vaginal or penile discharge (this might be yellow or green), and pain during urination. Women may experience discomfort in the lower abdominal region, and increased bleeding between or during periods; while men may notice inflammation of the foreskin or testicular pain.

Left untreated, the condition can cause fertility problems, so it is important to get tested for the condition if you think you have gonorrhoea, or suspect you have come into contact with it. Doing so will enable you to curb the development of harmful symptoms and limit the spread of infection.

As the illness is caused by a bacterial infection, gonorrhea is treated with antibiotic medication. Previously, doctors would routinely prescribe penicillin for the condition. However, over the past half-century, the bacteria responsible has become resistant to gonorrhoea treatments in this field, and more impervious strains have developed. Single antibiotics used on an independent basis are now less likely to clear up the infection. As a result, gonorrhoea is today more commonly treated with a combination of two antibiotics.

The best treatment for gonorrhea in the UK is an antibiotic injection, given with an antibiotic tablet. However, the injection for gonorrhea needs to be administered by a trained medical professional.

In certain circumstances a combination of two tablets is used to treat gonorrhoea. This is only recommended if the patient is unable or refuses to have the injection (for instance if they are needle-phobic, or allergic to anything in the injectable treatment).

Azithromycin and Suprax work in different ways to neutralise the infection. Bacterial cells need to perform certain functions in order to spread, and remain active. They need to: produce chemicals which enable them to maintain cellular structure and remain intact; and they also need to generate self-sustaining proteins, in order to multiply and increase in number.

The active constituent in Suprax is a compound called cefixime. This disrupts the stability of bacterial cell membranes, and creates gaps. As a result, cells cannot stop their contents from seeping out, and cannot stop other substances from outside the cell getting in.

Azithromycin negates the bacteria’s ability to produce an enzyme which it needs to replicate itself. Once the growth of the bacteria has been stopped, the body’s defences kill off what remains of the infection.

It will be necessary for you to be re-tested after finishing the course to ensure the infection has passed. We recommend taking a second re-test three weeks after your treatment has concluded. This is to allow for any trace of the infection to exit the body. During this time, you should not engage in sexual contact. 

If you think you may have contracted a gonorrhoea infection, you should get tested. You can do this by making an appointment with your doctor, or attending a GUM clinic. They will be able to give you tailored advice and issue a prescription, should it be required.

You can also order a home test kit from us here.

Please note that we only offer this treatment to patients with a positive test result for gonorrhoea. If you think you may have gonorrhoea, but have not been tested yet, we recommend you see your doctor or visit your sexual health clinic for guidance.

If you think you might have been exposed to gonorrhoea but haven’t been tested yet, you should do so as soon as you can. Testing is available through your local sexual health services. You can also buy gonorrhoea test kits online from us. We offer two types: one that enables you to collect a sample at home and gives you a result in 15 minutes; and another where you can provide a sample at home to be posted to our partner lab, and you’ll receive your results online within a few days.

The test kit and treatment combination pack we offer is for people who have already tested positive for gonorrhoea and require treatment, but want to order a retest online to take at least two weeks after completing treatment (test of cure).

If you have tested positive for gonorrhoea, you can take our questionnaire to see if this treatment is suitable for you. If your order is approved by our prescriber, your treatment will be shipped by next-day courier.

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Page last reviewed:  11/03/2021


When using the Gonorrhoea Treatment Pack or antibiotics of any kind, it is absolutely vital to adhere to the directions your doctor provides.

You should also familiarise yourself with the information supplied in the leaflet prior to first use. Taking the medicine as prescribed will enable you to get the most out of the treatment and lower the risk of side effects.

  1. Take this treatment as prescribed.
  2. This is a one off dose consisting of Suprax 400mg (two 200mg tablets) and Azithromycin 2000mg (four 500mg tablets).
  3. Do not drink alcohol before taking this medicine. 
  4. You should also not drink alcohol for a further 48 hours after taking it.
  5. Do not exceed the dose prescribed.
  6. Do not have sex until 21 days after you and your sexual partner(s) have completed treatment.
  7. To ensure the infection has passed, we would recommend getting tested again after you have used this treatment. You should wait at least three weeks before doing so.
  8. Refrain from having sex until you have been tested and told you are clear of infection.

Further information can be found in the leaflet provided. If you are still unsure how to take this medicine, ask your doctor or pharmacist.

Page last reviewed:  11/03/2021
Please read the patient information leaflet for this medicine fully before use:

Azithromycin, Suprax 500mg/200mg

Side effects & Warnings

Side Effects

If you notice anything unusual or experience side effects when using this treatment, seek medical advice as soon as possible. Side effects associated with these medicines include:

      1.  Azithromycin

Very common (1 in 10 people or more):

Abdominal pain, diarrhoea, nausea, flatulence.

Common (1 in 10 people or less):

Loss of appetite, headache, dizziness, pins and needles or numbness, visual impairment, loss of hearing, vomiting, stomach pain or cramps, skin rashes and itching, joint pain, fatigue.

Uncommon (1 in 100 people or less):

Fungal or bacterial infection, angioedema, hypersensitivity, drowsiness, insomnia, palpitations, shortness of breath, inflammation of the lining of the stomach, constipation, dry mouth, mouth ulcers, hepatitis, dermatitis, sweating, muscle pain, back or neck pain, painful urination, testicular disorder, urticaria, chest pain, facial swelling, fever, feelings of weakness, fluctuating liver enzyme levels and blood levels.

Rare (1 in 1,000 people or less):

Liver or kidney problems.

Very Rare:

Gut infection, haemolytic anaemia, anxiety, confusion, hallucinations, fainting, convulsions, feeling hyperactivity, muscle weakness, irregular heartbeat, low blood pressure, pancreatitis, discoloration of the tongue and teeth, liver failure, allergic skin reactions.

      2.  Suprax

Uncommon (1 in 100 people or less):

Blistering, flu-like symptoms, fever, blood disorder, allergic reaction, diarrhoea, feeling or being sick, stomach pains, indigestion, headaches, dizziness or itchiness.

The information provided here is not comprehensive. A more detailed list of side effects can be found in the leaflets supplied with each medicine.


Taking it with other medicines

The Gonorrhoea Pack may not be suitable for you to use if you are currently taking or have recently taken any of the following: ergotamine, statins, quinidine, cyclosporin, warfarin, cisapride, terfenadine, zidovudine, nelfinavir, rifabutin, alfentanil, antacids, theophylline, digoxin, astemizol or pimozide.

Let your prescriber know if you are taking these or any other medicines during consultation.

Conditions to look out for

When you buy gonorrhoea antibiotics from our online pharmacy, you will be presented with a simple health questionnaire. This forms part of our consultation process, and allows our doctor to review your medical history and suitability for this medication. Make sure you inform the doctor of any medical conditions or allergies you have had, past or present.

These medicines may not be suitable for you if you have a history of: diabetes; liver or kidney problems; bowel disease; severe heart problems; neurological or psychiatric illnesses.

Do not buy or use the gonorrhea treatment pack if you are allergic to antibiotics. In such cases you will need to discuss other treatment options with your GP.

Pregnancy and breastfeeding

If you are pregnant, breastfeeding or trying to conceive you should not use this combination of treatment unless explicitly told to by your doctor. If you have any concerns, speak with your GP.

Driving and machinery

This form of treatment should not interfere with your ability to drive or operate machines. However, if at any point you feel dizzy, you should make sure that the episode has passed before attempting to drive.

Lactose intolerance

Azithromycin contains lactose. Therefore if you have an intolerance to some sugars, you should speak to your doctor before using this treatment.

Nut allergy

Some versions of azithromycin are unsuitable for people with nut allergies. Make sure you let your prescriber know during consultation if you are allergic to anything, including nuts.

Page last reviewed:  11/03/2021
Please read the patient information leaflet for this medicine fully before use:

Azithromycin, Suprax 500mg/200mg


Can I still drink alcohol?

No. Alcohol may affect the efficacy of the medicine. You should allow at least 48 hours after using this medicine before drinking alcohol.

Will I still be able to drive?

If you experience no side effects, yes. However if you notice any side effects which may make driving dangerous, you should avoid doing so and contact your nearest doctor or healthcare professional immediately.

Can I use this medicine while pregnant?

No. These medications are not suitable for those who are pregnant or breastfeeding. Speak to your doctor about alternative treatment in these cases.

How do I store it?

In a cool, dry environment, below 25 degrees, and out of the reach of children.

Am I allergic to anything in the medicine?

Surpax contains cefixime, microcrystalline, phosphate dihydrate, magnesium stearate, hypromellose, cellulose, pregelatinised starch, calcium hydrogen, macrogol 6000 and titanium.

Azithromycin tablets consist of azithromycin dihydrate, croscarmellose sodium (E468), magnesium stearate (E572), microcrystalline cellulose (E460), silicium dioxide, (E551), poloxamer, povidone (E1201), talc, waterfree lactose, hypromellose (E464), hydroxypropylcellulose, macrogol and titanium dioxide (E171).

Do not buy this gonorrhoea antibiotics pack or use it if you are allergic to or unable to tolerate any of the above ingredients, and discuss treatment with your GP instead.

Please note that you may be unable to take some brands of azithromycin if you are allergic to nuts. Tell your prescriber about any allergies you have during consultation.

When can I have sex again? 

Only after you have waited for three weeks after the course of treatment has ended and you then take a subsequent re-test for gonorrhoea. 

Is it available over the counter?

This treatment is prescription only, which means that a doctor will need to assess your suitability before you are able to use it.

How can I get gonorrhoea treatment online?

Please note that we only supply this medicine to patients with a positive test result, who are unable to have the preferred treatment (injection). If you haven’t been tested, you can order a test kit online from us here. Otherwise, we recommend you visit your local sexual health services for advice. 

If you have received a positive test result for gonorrhoea, are unable to have the injection and would like to order gonorrhoea treatment online, you can do so using our confidential consultation facility. Click ‘buy now’ to go to our questionnaire and get started.

Page last reviewed:  11/03/2021
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