A New Treated is Coming. Read more.
Registered Pharmacy
24hr Free Delivery
No Registration Needed


Liothyronine sodium

Liothyronine sodium is a tablet treatment for hypothyroidism (or underactive thyroid) marketed by Mercury Pharma. It contains a synthetic version of a thyroid hormone.

To renew your prescription and buy Liothyronine sodium online, start your consultation by clicking ‘buy now’ and taking our questionnaire. Your request will be checked by a registered doctor and, once approved, dispensed and shipped from our UK pharmacy.

+3500 Trustpilot reviews
PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.

This content was reviewed by a clinician on

26 April 2022
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 26 April 2022
Product information

Liothyronine is a medicine used in hypothyroidism, or underactive thyroid. The active ingredient in the treatment is liothyronine sodium. This is an artificial version of the hormone liothyronine, and works by supplementing levels of this hormone in order to alleviate symptoms.

If you are already taking this treatment on the instruction of a specialist, and your thyroid function and treatment plan are stable, you can renew your prescription and buy Liothyronine sodium online using our secure consultation facility.

What is hypothyroidism?

Hypothyroidism is a chronic condition. It occurs when the thyroid gland does not generate a sufficient amount of the thyroxine (T4) or triiodothyronine (T3) hormones. The hormones play an important role in metabolism, so someone with an underactive thyroid may develop weight gain, constipation and feelings of fatigue.

Other symptoms of hypothyroidism might also include irregular periods in women, aching muscles, depression, and loss of libido.

According to the NHS, hypothyroidism is more common in women (affecting 15 out of 1,000) than it is in men (affecting one in 1,000). The condition tends to develop over time, usually as a result of the immune system attacking the thyroid gland. In other cases, treatments for thyroid cancer or an overactive thyroid might be the cause.

If you notice any symptoms which could indicate an underactive thyroid, you should see your doctor. They will be able to assess your thyroid function through testing, and initiate treatment where required.

What treatments are used for an underactive thyroid?

  • Levothyroxine

Levothyroxine (available as a generic and under the Eltroxin brand name) is a commonly issued treatment, and works as a form of hormone replacement therapy.

  • Liothyronine sodium

In other cases, Liothyronine might be issued as an alternative. In the body, thyroxine is converted into liothyronine; so liothyronine might be suggested by a specialist when someone has very low levels of thyroid hormone and needs quick supplementation.

Furthermore, the doses of this medication are not bioequivalent to levothyroxine; so it might be prescribed by a doctor in instances where someone is unable to get their dose of levothyroxine to a satisfactory level.

A prescription for Liothyronine needs to be started by a specialist, and monitored regularly. If you are not taking underactive thyroid treatment, and think you may be experiencing symptoms, speak to your doctor.

Can I buy Liothyronine sodium online?

Through our secure pharmacy service, we offer Liothyronine on a renewal basis to patients already taking it and who are stable on their treatment.

To buy Liothyronine online, complete our simple questionnaire. Your answers will be checked by one of our GMC-registered doctors, who will issue a prescription following approval, and send this to our dispensing pharmacy. Treatments are shipped by tracked next-day courier, so you can follow the progress of your order.

Page last reviewed:  26/04/2022

Make sure you read the patient information leaflet fully before use, and take this medicine according to your prescriber’s directions.

  1. Your specialist will decide on the most appropriate dose during your regular consultation with them.
  2. This will usually be between 10mcg and 60mcg per day, divided into several doses.
  3. Take the tablets with water.
  4. Your specialist consultant will need to monitor your condition regularly, and may need to adjust your dose.
  5. If you forget to take your dose at the usual time, skip it and take the next one at the scheduled time.
  6. Never double up on doses to make up for a missed one.

More information can be found in the patient information leaflet.

If you are unsure of anything, speak to your doctor or pharmacist for further advice.

Page last reviewed:  26/04/2022
Please read the patient information leaflet for this medicine fully before use:

Liothyronine 20mcg

Side effects

Side effects

Some patients may experience side effects when using this medicine.

Tell your doctor straight away if you develop any signs of an allergic reaction. This might include swelling of the face or throat, hives, or difficulty breathing.

You should also let your doctor know if you experience any other side effects, and let them know immediately if any of these becomes serious.

Side effects listed in the leaflet for this medicine include:

Sleep disruption, fever, being unable to tolerate heat, tremors, being sick, allergic reactions, pain in the chest, muscle cramps, diarrhoea, weight loss, headache or restlessness.


Taking it with other medicines

Your doctor needs to know about any other medications you are currently taking or have recently taken, as some may affect how this treatment works.

Liothyronine may interact with: anticoagulants, such as warfarin; insulin and diabetes medicines; anticonvulsants, such as phenytoin; cardiac glycosides such as digoxin; tricyclic antidepressants such as amitriptyline; cholestyramine; contraceptive pills; amiodarone; barbiturates; or primidone.

Conditions to look out for

Patients with certain conditions will not be able to use this treatment, whereas others may need to exercise caution and be closely monitored while taking it. Disclose your medical history to your prescriber during consultation.

You should not take Liothyronine if you: have a heart or circulatory condition, such as angina; are allergic to anything in the medication; or have thyrotoxicosis.

This medication will need to be used with caution in patients who are pregnant or breastfeeding, are elderly, or who have had low thyroid levels for a long time. It will need to be taken with special care in patients who have: diabetes; myxoedema; heart problems; high blood pressure; or have developed symptoms as a result of starting thyroid treatment, such as loose stools or a raised heart rate.

Pregnancy and breastfeeding

If you are pregnant, breastfeeding, or plan to become pregnant, you should speak to your doctor in person before using this treatment.

Driving and machinery

There is no information in the leaflet regarding the possible effects this medication may have on driving, or capacity to use machines.

If you experience any side effects which might inhibit your capacity to drive, do not drive and speak to your doctor.

Lactose intolerance

Lactose is an excipient ingredient in this drug. If you have an intolerance to any sugars, let your doctor know before taking it.

Page last reviewed:  26/04/2022
Please read the patient information leaflet for this medicine fully before use:

Liothyronine 20mcg


Can I still drink alcohol?

There is no specific information in the leaflet for this medication on alcohol use. If you plan to drink alcohol while taking it, ask your doctor for advice.

Will I still be able to drive?

If you develop any side effects which could impede your ability to drive, refrain from doing so and see your doctor.

Can I take the medicine while pregnant?

If you are pregnant or breastfeeding, or if you become pregnant while using this treatment, ask your doctor or specialist for advice.

How should I store it?

Keep out of direct sunlight, out of the reach of children.

Am I allergic to anything in the medicine?

This medicine contains: liothyronine, lactose, maize starch, powdered acacia, magnesium stearate, sodium chloride, industrial methylated spirit and purified water.

Do not take it if you are allergic to any of the above.

Is it available over-the-counter?

No. Liothyronine is prescription only.

Is it right for me?

Your specialist consultant will determine the most suitable treatment for you, during your regular check-up with them. They will need to monitor your thyroid function through testing, and adjust your dose accordingly; so if you think you may be developing underactive thyroid symptoms but have not seen a doctor, or if you are taking treatment but your symptoms have changed, you should arrange to see your GP or specialist in person.

Our service enables you to renew your prescription and buy Liothyronine sodium online. Take our questionnaire to begin your secure consultation. One of our doctors will review your request, and issue a prescription on approval. This will then be sent to our UK pharmacy to be dispensed, before being delivered by special next-day parcel.

Page last reviewed:  26/04/2022
Treated.com is rated 4.9 out of 5 by 3466 customers on TrustPilot!
A simple process
Getting the treatment you need has never been easier with our speedy and simple online service.
  • Search for your medicine

    Find the treatment you need.
  • Fill in a simple questionnaire

    A GMC-registered doctor or a pharmacy prescriber will review your answers.
  • 24h delivery to your door

    Next-day delivery. Every order is sent by tracked courier.
  • Repeat ordering is easy

    We keep your details secure so you can reorder with ease.

No matches found. You can find all our treatments here