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Alli is a weight loss pill made by GlaxoSmithKline (GSK). It is used in conjunction with diet and exercise to help the user lose weight.

Getting the treatment you need is simple with our secure consultation service. Once our pharmacist has approved Alli, you’ll typically receive it within 2-3 business days.

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In this tablet is 60mg of orlistat. Usually one tablet is taken three times per day, either just before, during, or within one hour after a meal.

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Alli is a weight loss pill made by GlaxoSmithKline (GSK). It is used in conjunction with diet and exercise to help the user lose weight.

Getting the treatment you need is simple with our secure consultation service. Once our pharmacist has approved Alli, you’ll typically receive it within 2-3 business days.

This content was reviewed by a clinician on

08 September 2020
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 08 September 2020
Product information

What is Alli (Orlistat 60mg)?

Alli is a tablet for weight loss marketed by GlaxoSmithKline. It contains an ingredient called Orlistat, which works by reducing the amount of fat your body absorbs from meals. It should only be used as part of a larger weight loss programme, which includes a healthy, balanced, low-calorie diet, and physical activity. The medication is only suitable for use by those who have a BMI of 28 or over.

Whether or not a person is a healthy weight can in most cases be determined by their Body Mass Index (BMI). This is calculated using the person’s height and weight. The majority of people fall into one of three categories, which are:

  1. healthy weight (BMI of 18-25)

  2. overweight (BMI of 25-30)

  3. or obese (BMI of 30 and over)

Nearly two thirds of the UK population is either overweight or obese. Those who are overweight or obese are at increased risk of developing serious health issues, including heart disease, stroke, diabetes, and some types of cancer. Being obese can also cause low self-esteem, and lead to psychological issues such as depression in some cases.

Someone who is overweight or obese can reach a healthier, safer weight by adopting a programme of controlled weight loss. This will typically consist of a healthy diet which is lower in calories, combined with a programme of exercise. It’s important for those losing weight to aim to do so at a gradual rate, so that they do not risk illness by losing weight too quickly.

Your doctor can help you put together a healthy eating and exercise programme to suit your needs, and help you lose weight at a safe rate. However, in cases where these measures alone have not succeeded, and someone’s weight may be putting their health at risk, then weight loss medicine such as Alli may be recommended.

This particular treatment is only suitable for first time users with a BMI of 28 or above. Those who have already begun the course and are losing weight can be prescribed the treatment if they have a BMI which is slightly lower.

Six months is the maximum duration someone can take Alli capsules for. A healthcare professional may choose to review your progress after you have been using the treatment for 12 weeks, before issuing the remainder of the course.

The active ingredient in Alli capsules is orlistat, which works in the gut to reduce the amount of fat you absorb from food. It is thought to lower fat absorption by roughly a quarter (some therefore refer to Alli as a 'fat-blocker'). This fat, which is consequently not taken up by the gut, is instead passed out of the body through faeces. The manufacturers of Alli state that for every 2kg lost through dieting, the tablet can assist in the loss of a further 1kg.

To buy Alli from our pharmacy, you will need to undergo consultation with our physician to make sure it is safe for you to use. Our secure online doctor service enables you to get the prescription treatment you need quickly and safely. Each order is checked by a practising healthcare professional, who will only approve your prescription if they are satisfied the medication is suitable for you. Medicines are dispensed at our UK-based pharmacy, before being shipped by tracked courier.

Please note that you will need to begin your new lower calorie diet a few days in advance of starting treatment with Alli. Orders for Alli which are approved at our pharmacy will usually arrive within 2-3 business days.

Please also note that when you take our consultation for Alli, your questionnaire will be reviewed by our pharmacist, not our doctor.

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Page last reviewed:  08/09/2020 | Next review due:  03/06/2019



Make sure you read the instructions provided with the medicine before you use it. This will help you to limit the chances of side effects, and help the treatment to work at its best.

  1. Take as directed by your doctor.
  2. Select a day when you will begin taking Alli capsules a few days in advance.
  3. Begin your lower fat and calorie diet before starting the treatment, so that your body has enough time to adjust.
  4. Set a target weight you want to reach. Your doctor may be able to help you do this. Typically, you might aim to reduce your weight by between 5 and 10%.
  5. A gradual rate of weight loss is considered the most healthy. A doctor may advise that you try to aim for around 0.5kg per week.
  6. Remember that physical activity plays a crucial role in your weight loss programme.
  7. One Alli tablet is taken, three times per day.
  8. To be effective, Alli tablets need to be taken either just before or during a meal, or up to one hour following a meal.
  9. If you skip a meal or if the meal you are eating is fat free, do not take the tablet.
  10. Swallow tablets with water. Do not chew.
  11. Do not exceed the stated dose.
  12. If you miss or forget a dose, consult the patient information leaflet for guidance.
  13. Six months is the maximum length of time someone can take Alli for.
  14. If the medicine and the programme you are following has not produced satisfactory results in 12 weeks, consult your doctor.
  15. Once you have completed the course, you will need to maintain healthy diet and exercise habits to help you stay at your target weight. Your doctor can provide advice to assist you in this.

More detailed directions can be found in the leaflet supplied with the medicine.

Download Alli Patient Information Leaflet.

Page last reviewed:  08/09/2020 | Next review due:  03/06/2019
Please read the patient information leaflet for this medicine fully before use:

Alli 60mg

Side effects & Warnings

Side Effects


Not everyone who uses this medicine will have side effects. However, you should still be aware of these in case they occur, and so that you can get medical help if necessary.

Seek medical advice immediately if you notice any signs of an allergic reaction, such as facial swelling, a rash, itching, fast heartbeat, or difficulty breathing.

Stop using the medicine and talk to your doctor as soon as possible if you notice: rectal bleeding; signs of diverticulitis, such as lower stomach pain, fever and constipation; signs of pancreatitis, which might be abdominal pain radiating towards the back, fever, and sickness; blistering; severe stomach pain as a result of gallstones; or symptoms of hepatitis, such as yellowing skin and eyes, itching, discoloured urine, stomach discomfort and liver tenderness.

Other side effects:

Very common (1 in 10 or more):

Flatulence, sudden bowel motions, fatty or oily soft stools.

Common (1 in 10 or less):

Stomach pain, increased bowel frequency, runny stools, anxiety, headache, hypoglycemia, menstrual disturbances, urinary tract infections, tooth disorders, infections of the respiratory tract.

This is only a summary of the side effects associated with this medication. Please see the patient leaflet for more information.

Taking it with other medicines

Do not take Alli with: ciclosporin; acarbose; or blood-thinners such as warfarin.

Tell your prescriber if you are using (or have recently used) any of the following, as the efficacy of Alli or of the following may be affected, and your treatment may need to be adjusted: amiodarone; thyroid medicines such as levothyroxine; medicines for epilepsy; treatments for HIV; antidepressants; high blood pressure medication;or high cholesterol.

Users taking the contraceptive pill should consider using a barrier method for extra protection, as the pill may be less effective where diarrhoea is present.

If you are using Alli, you are also advised to take a multivitamin (containing A, D, E and K) at bedtime, as the medication can lower the absorption of some vitamins.

Refer to the leaflet provided for more information.

Conditions to look out for

This treatment is not suitable for: those with allergies to any of the ingredients in the medicine; women who are pregnant or breastfeeding; those taking ciclosporin; those taking warfarin or other medicines used to thin the blood; those with cholestasis; or those who have chronic malabsorption syndrome.

Your doctor also needs to know if you have diabetes or kidney disease, as these conditions may affect your capacity to use this medicine.

Vitamin levels

This medicine can affect vitamin levels in the body; particularly vitamin D. You should therefore speak to your doctor about supplementing these levels when taking this medication. It may be necessary for you to take a multivitamin and take certain other steps to ensure your levels stay healthy. Speak to your doctor right if you feel constantly tired or lethargic.

Pregnancy and breastfeeding

Do not take Alli if you are pregnant, breastfeeding or trying to conceive.

Driving and using machinery

Your capacity to drive or use machinery is not likely to be affected by this medication.

Food, drink and alcohol

There are specific instructions regarding food which need to be followed when using this treatment for it to be effective. Please read the information provided in the leaflet carefully.

Page last reviewed:  08/09/2020 | Next review due:  03/06/2019
Please read the patient information leaflet for this medicine fully before use:

Alli 60mg


Can I still drink alcohol?

Yes, but it is advisable to do so only in very strict moderation, as over-consumption may compromise your weight loss goals.

Will I still be able to drive?

Yes, provided you experience no side effects that inhibit your capacity to drive. If you do notice any side effects which could affect your judgement or coordination, do not drive and tell your doctor immediately.

Can I take the medicine if I’m pregnant?

This treatment should not be used during pregnancy. It is also not suitable for breastfeeding mothers.

How should I store it?

Keep it in a safe place, below 25°C and out of the reach of children.

Am I allergic to anything in the medicine?

This medication contains: orlistat, microcrystalline cellulose (E460), sodium starch glycolate, povidone (E1201), sodium laurilsulfate, talc, gelatin, indigo carmine (E132), titanium dioxide (E171), sorbitan monolaurate, black ink (shellac, iron oxide black (E172), propylene glycol), and polysorbate 80.

Do not use it if you are allergic to any of these ingredients.

Is it available over-the-counter?

It is possible to buy Alli over the counter, however you will still need to undergo a short consultation when buying the medication in person or online. This is so that a healthcare professional can make sure the treatment is suitable for you to use.

Is it right for me?

Our service has been designed to help you find the right treatment, or renew existing prescriptions for your medicine with safety and ease. If you are looking to buy Alli from a UK registered pharmacy, take our medical questionnaire today and our pharmacist will review your responses. Orders for Alli are typically delivered within 2-3 business days.

Page last reviewed:  08/09/2020 | Next review due:  03/06/2019 is rated 4.9 out of 5 by 3259 customers on TrustPilot!
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