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Fybogel Mebeverine

Mebeverine Hydrochloride/Ispaghula Husk

Fybogel Mebeverine is a powder treatment which is mixed with water to create an oral solution. It alleviates symptoms of constipation by boosting fibre content in the gut.

It isn’t always easy seeking treatment for certain conditions in person. Our simple online service enables you to get the product you need delivered straight to your door.

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PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.

This content was reviewed by a clinician on

28 August 2020
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 28 August 2020
Product information

Fybogel Mebeverine is a powder medication made by Reckitt Benckiser, and is mixed with water to make a drinkable solution. It is designated for the treatment of IBS symptoms, including constipation. The solution is taken twice a day, most typically in the morning and the evening, although in some cases a doctor may suggest a third dose being taken at or around midday. Purchase of Fybogel Mebeverine through our online service can only be made after consultation with a doctor.

  1. Reduces constipation
  2. Provides relief from IBS symptoms
  3. Easy two to three a day dose

Constipation is a condition which can have any number of causes, and is characterised by a severely reduced bowel frequency. It is common for stools to be dry and hard, due to the increased water absorption caused by their lingering presence in the gut. Feelings of bloatedness may also be present, as might stomach pain. Poor dietary habits, such as not eating enough fibre or eating infrequently, and a lack of fluid intake can sometimes cause constipation symptoms.

In IBS, someone may flit between bouts of constipation and diarrhoea. This condition is, in simple terms, an increased susceptibility to bowel problems, which can cause difficulties digesting food. Someone with IBS, or irritable bowel syndrome, may find that they experience symptoms after eating a certain type of food, causing them to either process food too quickly, or too slowly. It is in the latter case where constipation may develop.

Prevention of constipation and non-medicinal treatment depends on the cause. Milder cases may be resolved by increasing fibre intake, or increasing the amount of fluid you drink if you aren’t getting enough. In the case of IBS, it may be necessary to identify those specific foods which trigger symptoms, and limit or even stop their consumption.

Treatment for IBS-related cases of constipation may be necessary where symptoms persist. Fybogel Mebeverine is a combination medication, which contains two active constituents; ispaghula husk and mebeverine hydrochloride. The first of these is a fibre, which works as a laxative to provide bulk to the food present in the gut. In doing so, it encourages the muscles in the bowel to react by pushing the food out, increasing stool frequency. Mebeverine is a type of drug called an antispasmodic, and relieves digestive pain by helping the muscles in the gut to relax.

We know it can be tricky seeking medications for some conditions in person, or simply inconvenient taking a day off work to see your doctor. This is why we’ve developed our easy-to-use consultation service, so that you can get the treatment you need from the comfort of your own computer. All you need to do is fill in our confidential medical questionnaire, and your answers will be assessed by one of our GPs. Once approved, orders are then sent to our pharmacy and dispensed, before being shipped by tracked next-day courier.

Page last reviewed:  28/08/2020


Following the directions provided by your prescriber is vital when applying this treatment, as is adhering to those supplied in the patient information leaflet. This will help you to limit the risk of possible side effects and maximise the efficacy of the product.

  1. Take as prescribed by your doctor.
  2. For cases of constipation related to IBS, the sachets should be taken once in the morning, and once in the evening.
  3. In some instances a doctor may suggest taking a third dose at lunchtime.
  4. The dose should always be taken half an hour before food.
  5. Mix the contents of one sachet with 150ml of water (one quarter of a pint) and stir well, until all the granules have dissolved.
  6. Drink immediately.
  7. Your prescriber will tell you how long the duration of treatment should last.
  8. If symptoms persist beyond two weeks of use, then you should tell your doctor.
  9. Do not take more than the amount specified by your prescriber.
  10. Those who forget to take a dose should skip the one they have missed and carry on the course as normal.

Please note that the above is provided only as a guide. More detailed instructions can be located in the leaflet supplied with the product.

Page last reviewed:  28/08/2020
Please read the patient information leaflet for this medicine fully before use:

Fybogel Mebeverine 135mg/3.5g

Side effects & Warnings

Side effects

Inform your doctor right away if you notice any signs of an allergic reaction, such as: hives, an itchy rash, swelling of the face, lips, mouth or tongue, or difficulty breathing.

Flatulence and feelings of bloatedness may occur within the initial few days of treatment, but these should dissipate after a short period.

Consult the leaflet provided for more information on side effects.


Taking it with other medicines

Your prescriber needs to be made aware during consultation of you are using: diuretics; or potassium supplements.

Conditions to look out for

Do not take this item if you have: an obstruction in the bowel; a faecal impaction; decreased bowel activity caused by paralytic ileus; muscle weakness in the bowel wall; or phenylketonuria.

It may also not be suitable for those who: have any condition which affects bowel movements, such as megacolon; have never had symptoms of irritable bowel syndrome before and this is the first time they are having them; are aged 40 years or over; are passing blood from the bowel; are feeling or being sick; have loss of appetite or have lost weight; are looking pale and feeling tired; have severe constipation; have a fever; have recently travelled abroad; have abnormal vaginal bleeding or discharge; are experiencing urinary problems; or have porphyria.

Pregnancy and breastfeeding

Speak to your doctor before using Fybogel if you are pregnant or breastfeeding.

Page last reviewed:  28/08/2020
Please read the patient information leaflet for this medicine fully before use:

Fybogel Mebeverine 135mg/3.5g


Can I still drink alcohol?

Yes, technically, as it is not likely to interact with the treatment. However, we would advise against the consumption of alcohol if you are experiencing bowel problems.

Will I still be able to drive?

Yes, provided you experience no side effects which make doing so dangerous. If you do, then you should not drive and tell your doctor as soon as possible.

Can I take the medicine while pregnant?

Seek advice from your doctor before using this treatment if you are pregnant or breastfeeding.

How should I store it?

Keep it in a safe place below 30°C.

Am I allergic to anything in the medicine?

This product contains: ispaghula husk, mebeverine hydrochloride, potassium hydrogen carbonate, sodium hydrogen carbonate, microcrystalline cellulose, basic butylated methacrylate copolymer, sterilised talc, polyethylene glycol 6000, citric acid, polysorbate 80, silica colloidal anhydrous, saccharin sodium, aspartame E951, orange flavour and beta-carotene, riboflavine sodium phosphate and apo-carotenal colouring.

Do not take it if you are allergic to any of the above ingredients.

Is it available over-the-counter?

To buy Fybogel Mebeverine from our UK pharmacy, you will require a prescription. Fill in our medical questionnaire to have your case reviewed by one of our practitioners.

Is it right for me?

Our service is ideal for those looking to get fast and secure access to the treatment they need. Simply fill in our health assessment, and once our doctor has reviewed and approved your order, a prescription will be drawn up and sent electronically to our dispensing pharmacy. Delivery on all items is made by tracked courier, so that you don’t have to wait to receive your treatment. 

Page last reviewed:  28/08/2020 is rated 4.9 out of 5 by 3131 customers on TrustPilot!
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