Caverject

Alprostadil

Caverject is a single use erectile dysfunction treatment, designed to be injected into the base of the penis.

We do not offer this treatment online. To be prescribed Caverject, we recommend you see your GP in person.

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PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.
Description

Caverject Vials / Dual Chamber

Caverject is an injectable drug, indicated for the treatment of erectile dysfunction. It is available to buy from our online pharmacy in two forms, as Caverject Vials and as Caverject Dual Chamber. Both perform the same function, but are applied in slightly different ways, and provided in different strengths.

  1. Noticeable differences in as little as 5 minutes
  2. Available in two forms
  3. Simple to use injections

When you buy Caverject injection vials you get: a vial containing the active ingredient alprostadil in the form of a powder; a syringe containing the mixing solution; and two types of needles. The larger needle is used to insert the liquid into the vial containing the powder; and once this has dissolved, the smaller needle is used to inject the mixed solution into the base of the penis.

Those who buy Caverject dual chamber will receive injections that do not require assembly. The medicine is activated when the two chambers mixed together.

What is ED?

Impotence is a taboo subject for many men, but that doesn’t make it any less common. Most men will experience erectile dysfunction at some point in their lives. It’s important to keep in mind that ED can be caused by almost anything, such as the presence of conditions like diabetes, or anxiety, or the consumption of alcohol.

It is a common misconception that the condition only hits after a certain age. Granted, the condition is more widespread among older men, due to health and lifestyle factors which tend to run alongside the ageing process, such as raised cholesterol and increased blood pressure. But it is not uncommon for younger men to come into contact with ED. One of the main causes of the condition among men in their 20s and 30 is mental strain. A job may be causing anxiety, or pressure to perform well sexually may be making one feel self-conscious, and obstructing erectile potency.

Biologically, erectile dysfunction is most typically a result of the restriction of blood flow to the penis. This can be a consequence of muscle walls inside blood vessels close to the penis tightening up, and not letting enough blood through.

How does Caverject work?

The active ingredient in Caverject is a medicine called alprostadil, which works in a comparable way to a hormone present in your body called prostaglandin E1 (PGE1). This hormone is responsible for the easing and dilation of blood vessels, which in cases of ED, can become constrictive and hinder erectile performance.

After being injected into the base of the penis, alprostadil encourages these blood vessels to dilate, allowing for easier circulation and increased erectile function. Alprostadil should only cause erections if you are sexually stimulated. Other products, including MUSE, also contain this active ingredient.

Which dose should I use?

Caverject Vials come in the form of a 10 mcg, 20 mcg or 40 mcg injection vial; or you can buy Caverject Dual Chamber in either 10 or 20 microgram strength packs. The strength you use will depend on whether you have tried using the medicine before, and whether it was effective.

To test suitability of the treatment, when you buy Caverject Vials for the first time you might be advised to use the 10 microgram injection, provided you have no pre-existing medical conditions. A 5 microgram injection used to be prescribed but this dose has been discontinued by the manufacturer. If the treatment causes no side effects, a doctor may prescribe the same dose when more is required, or a stronger dose if necessary.

In cases of Caverject Dual Chamber, a doctor may typically prescribe the 10 microgram pack for first time users. If you have tried this version before and experienced no side effects, but found that it was less than fully effective, then your doctor might suggest trying the stronger 20 microgram pack.

Stay safe when buying online

Ordering medicines online should always be undertaken with the utmost care. It is important to ensure that the website you are buying from can fulfil your order, and is operating legally.

Some online pharmacies may claim that you can buy Caverject from them as a generic alprostadil injection. However, no licensed generic form of the medication is currently available.

It is also not possible to buy Caverject at the NHS levy rate at present, as it is not available on NHS prescription. 

To protect yourself from fraudulent practices when you buy erectile dysfunction medicine online, you should only ever use GPhC-registered pharmacies staffed by qualified prescribers.

Please note that we do not offer Caverject through our online service. To be prescribed this item safely, we recommend that you make an appointment with your doctor in person.

Page last reviewed:  Wednesday, Aug 30 2017
Directions

Directions

Caverject needs to be administered in a specific way to help reduce the risk of possible side effects. Following the guidelines below and acquainting yourself with the patient information leaflet will help you to get the most out of your treatment.

Caverject Vials:

  1. Prior to using Caverject Vials for the first time, it is important that a qualified doctor or nurse demonstrates how to use it on at least one occasion.
  2. Application instructions can be found in the patient information leaflet. However these should only be used as a reminder. Reading this is not a substitute for physical demonstration from a healthcare professional.
  3. The packet will contain two injections: the larger one is used to mix the medicine; whereas the smaller one is used to administer the medicine.
  4. Once mixed, the contents need to be injected directly into the base of the penis.
  5. Never use more than the amount prescribed for you by your doctor.
  6. Never use this treatment more than once a day or three times a week.
  7. If you are unsure about anything before or during the use of this medicine, speak to your doctor or pharmacist.

Caverject Dual Chamber

  1. Before first use, a doctor or nurse should demonstrate how to use Caverject Dual Chamber.
  2. A step-by-step guide can be found in the patient information leaflet if you need a refresher.
  3. The injection should be prepared before injecting; this can be done up to 24 hours in advance.
  4. Caverject Dual Chamber is administered into the base of the penis.
  5. Never exceed the prescribed dose.
  6. Carefully read the patient information leaflet provided before using this treatment.
  7. If you are unsure about any aspect of this treatment, ask your doctor.

Download Caverject Vials patient information leaflet

Download Caverject Dual Chamber patient information leaflet

Page last reviewed:  Wednesday, Aug 30 2017
Side effects & Warnings

Side effects

No medicine is 100 percent risk free when it comes to side effects. Although most men will experience no issues when using Caverject, it is important to be aware of the risks present, so that you can act and get help in the event that side effects do occur. Here is a list of some of the known possible side effects associated with this medicine:

Common (1 in 10 people):

Painful erections.

Uncommon (1 in 100 people):

Swelling or skin discolouration at site of injection, prolonged erections, tender lumps, scarring or misshapen penis (seek medical attention right away if you notice any physical irregularities on or around the penis, or get an erection which won’t go away).

Rare (1 in 1000 people):

Pupil dilation, nausea, dry mouth, irritation of the skin, passing blood with urine, painful urination, feelings of heat in the penis.

The information listed above is not a complete account of the known side effects which this medication may cause. For a more definitive list of side effects, please refer to the patient information leaflet, or speak to your doctor. If you experience any of the above side effects, speak to a medical professional immediately.

Taking it with other medicines

During consultation, you should tell your doctor about any medicines you are taking, whether they are prescription or non-prescription medicines, or remedies. You should not begin or stop taking medication when using this treatment without consulting your prescribing physician first.

Inform your prescriber if you take: antihypertensives, sympathomimetics, high blood pressure medicines, or anticoagulants. Do not take Caverject Vials with any other medications for impotence.

Conditions to look out for

Before using the treatment, let your doctor know if you have, or have had, any of the following: blood-related illnesses, penile implants, any condition which inhibits your ability to perform vigorous exercise, any form of penile problems such as scarring, a deformity or Peyronie’s disease, lung, chest or heart conditions, mental illness, addiction, or stroke.

Again, this is not a comprehensive list of restrictions. In the interests of safety, disclose your full medical history during consultation so that your doctor can make an informed decision about whether this medication is suitable for you to take.

Pregnancy and breastfeeding

This item should not be used by women.

It is suitable for use in men whose partner is pregnant or breastfeeding.

Driving and using machines

Caverject is not likely to inhibit your capacity to drive or use machines.

Sexually transmitted infections

Please note that use of Caverject can cause a small amount of bleeding at the injection site, which can increase the risk of transmitting infections. Safe sex practices such as using condoms can lower the risk of transmission. For further guidance, ask your doctor.

Page last reviewed:  Wednesday, Aug 30 2017
Please read the patient information leaflet for this medicine fully before use:

Q&A

Can I still drink alcohol?

Technically yes, as there are no known direct interactions between Caverject and alcohol. But drinking alcohol can reduce your ability to get an erection, so we would advise against it when using this treatment.

Will I still be able to drive?

Caverject only works for a short period of time, so should not affect your ability to drive. However, there is a chance that you may experience side effects which might make it dangerous to drive, and in these cases you should refrain from doing so and speak to a doctor right away.

How should I store it?

Keep Caverject in a cool, dry storage environment, below 30 degrees. The medicine should be stored in its original packaging to protect it from sunlight and moisture.

Am I allergic to anything in the medicine?

As well as the active ingredient alprostadil, Caverject also contains lactose, sodium citrate, hydrochloric acid and sodium hydroxide. If you are allergic to any of these ingredients, do not use this treatment.

Is it available over-the-counter?

Caverject can only be bought with a prescription in the UK. This means a doctor will need to write a prescription for you before a pharmacy can legally issue this medication. 

Caverject is not available to buy through our pharmacy at this time.

Is it right for me?

Talk to your doctor if you want to know more about Caverject. They will be able to help you determine whether it is suitable for you, and issue a prescription where required.

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Page last reviewed:  Wednesday, Aug 30 2017
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