Registered Pharmacy
24hr Free Delivery
No Registration Needed



Losec Capsules and Losec MUPS are treatments for heartburn and other conditions related to gastroesophageal reflux disease, or GORD.

Getting your regular heartburn treatment doesn’t have to be a hassle. Take our questionnaire today to have your case reviewed by a registered practitioner. Once approved, we’ll deliver your treatment in just one working day.

+3100 Trustpilot reviews

Your consultation starts here

Did you have a dose and amount in mind?

Losec Capsules10mg

The 10mg strength capsule may be issued as a starting dose for heartburn. Take as directed by your doctor.

+ Free 24 Hr Delivery
Losec Capsules20mg

Contain 20mg of omeptrazole. Take according to your prescriber's directions.

+ Free 24 Hr Delivery
Losec Mups10mg

The 10mg MUPS tablet is a starting dose for those who are unable or prefer not to use whole capsules. They are taken as directed.

+ Free 24 Hr Delivery
Losec Mups20mg

20mg MUPS tablets may be used where oesophageal damage has occurred. Take as prescribed.

+ Free 24 Hr Delivery
Losec Mups40mg

The maximum dose of 40mg may be issued where smaller doses have not worked to effectively reduce symptoms. Take as directed by your doctor.

+ Free 24 Hr Delivery

You can highlight a preferred treatment, dose or amount to our prescriber, but to ensure your safety the final decision on any treatment you are offered is always the prescriber's. After your consultation, our prescriber may suggest a different treatment, or dose or amount of treatment (or not recommend treatment at all).

Please note: this service is not to be used in an emergency. Call 999 if you need urgent medical attention.
Order now, and get it by Saturday 25th September

Losec Capsules and Losec MUPS are treatments for heartburn and other conditions related to gastroesophageal reflux disease, or GORD.

Getting your regular heartburn treatment doesn’t have to be a hassle. Take our questionnaire today to have your case reviewed by a registered practitioner. Once approved, we’ll deliver your treatment in just one working day.

This content was reviewed by a clinician on

31 August 2020
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 31 August 2020
Product information

Losec is a capsule treatment indicated for heartburn, made by AstraZeneca. It works by inhibiting the production of gastric acids in the stomach. This function makes it adept at tackling occasionally related digestive issues, such as duodenal and stomach ulcers, and acid regurgitation.

  1. Branded AstraZeneca Product
  2. Sold as capsules or easy to take pellets
  3. Effective medicine for heartburn

The treatment is available to buy from our UK pharmacy as a standard capsule, and as a Losec MUPS tablet. An abbreviation for Multiple Unit Pellet System, this version is a capsule containing small pellets. Those who prefer not to swallow whole capsules or for whom this is difficult, these special tablets can be opened, and the contents can either be taken directly with water, or dissolved in liquid and swallowed.

Heartburn is characterised by pain, or the feeling of burning in the chest. It is a common symptom of a condition called gastroesophageal reflux disease, which can also cause discomfort when swallowing; and the bringing up of acid into the mouth, signified by an unpleasant taste.

There are a few reasons why someone might get heartburn, and most people throughout their lives will experience it at least once. It is more likely to occur when the stomach is too full (for instance after consuming a very large meal) or if a person is overweight. Pregnant women are also more susceptible to it.

At the base of the oesophagus where it connects to the stomach are a series of muscles. These form something called the oesophageal sphincter, and act as a doorway to the stomach; opening to let food in; and closing again to stop acids from getting out. Heartburn occurs when pressure is placed on these muscles, and they are unable to contract afterwards, leading to the upwards leaking of acids into the oesophagus. This then causes the aforementioned feelings of pain, and in more severe cases, inflammation and damage.

(In some cases, burning pain in the chest may be a symptom of a heart condition. If you are having chest pain for the first time, or if you are experiencing pain which is more serious than usual, you should go to your doctor right away to have your heart function checked.)

The functioning constituent in Losec is a proton pump inhibitor called omeprazole. Proton pumps are located within the cells of the stomach lining, and they generate acid to help digest the food we eat. Omeprazole works by lowering the amount of acid these pumps produce, and thereby decreasing the symptoms of GORD, including heartburn.

These tablets may also be issued in combination with antibiotics to treat an illness called helicobacter pylori, which is an infection with the potential to cause ulcers.

It’s never been easier to get your repeat prescription and buy Losec Capsules online. Take our questionnaire today, and if our GMC-registered doctor finds this treatment suitable for you, we’ll deliver it to your door within just one working day. Every item we sell is dispensed by a UK-based pharmacy, and shipped using secure, tracked parcel services.

Select dose
Page last reviewed:  31/08/2020


Follow the directions issued by your prescriber when using this product. This will help to make sure the treatment is as effective as possible. To help you lower the likelihood of potential associated side effects, you should also read and adhere to the guidelines provided in the patient information leaflet.

  1. Take as directed by your doctor.
  2. For cases of persistent heartburn, this might be a starting dose of one 10mg tablet per day. 
  3. In the case that the user has sustained damage in the oesophageal tract, a higher dosage of 20mg, or in some cases 40mg, may be prescribed.
  4. A typical course lasts for 4-8 weeks.
  5. The treatment of ulcers may require an adjusted dose.
  6. If using capsules, swallow these whole with water.
  7. The MUPS tablet version can be carefully opened, and the interior pellets can be swallowed, or dispersed in liquid before being consumed. See the leaflet supplied for further directions.
  8. Never take more than the amount prescribed for you by your doctor.
  9. If you forget to take Losec, you can do so when you remember, as long as your next scheduled dose is not imminent. If it is, skip the dose you have missed and take your next administration as normal.

This is only a summary of the directions you will need to follow when using this item. Consult the instructions supplied in the leaflet before use.


Page last reviewed:  31/08/2020
Please read the patient information leaflet for this medicine fully before use:

Losec Capsules 10mg

Losec Capsules 20mg

Losec Mups 10mg

Losec Mups 20mg

Losec Mups 40mg

Side effects & Warnings

Side effects

Notify your doctor right away if you get any side effects which concern you. In particular, you should seek urgent medical attention if you experience anything which may indicate an allergic reaction, severe skin disease or hepatitis. Further details of what these signs look like can be found in the patient information leaflet.

Common (1 in 10 people or less):

Headache, diarrhoea, stomach pain, constipation, wind, or feeling sick or being sick.

Uncommon (1 in 100 people or less):

Swelling of the feet and ankles, insomnia, dizziness, pins and needles, sleepiness, vertigo, changes in blood tests for liver function, rash, hives, itching, or fatigue.

Rare (1 in 1,000 people or less):

Reduced presence of white blood cells or platelets, allergic reactions, low sodium levels, mood swings, changes in sense of taste, blurred vision, sudden wheezing or shortness of breath, dry mouth, thrush, liver problems, hair loss, sensitivity to light, joint or muscle pains, severe kidney problems or increased sweating.

The above is only a selection of the side effects associated with this treatment. Please consult the more detailed list contained in the leaflet provided before use.

Taking it with other medicines

Losec is not suitable for use in conjunction with nelfinavir.

You should let your doctor know when filling in our online consultation form about any other treatments you are currently using, especially the following, as they may interact with this item or affect its function: certain antifungals, such as ketoconazole, itraconazole, posaconazole or voriconazole; digoxin; diazepam; phenytoin; some types of blood thinning agent, such as warfarin or other vitamin K blockers; rifampicin; atazanavir; tacrolimus; St John’s wort; cilostazol; saquinavir; clopidogrel; erlotinib; or methotrexate.

Conditions to look out for

Inform your prescriber when taking our questionnaire if you have a history of any medical conditions, as some may inhibit your capacity to use this product safely.

Do not take Losec if you are unable to tolerate other products of the same type, such as pantoprazole, lansoprazole, rabeprazole or esomeprazole.

Our practitioner also needs to know if you have or have ever had: severe weight fluctuations; problems swallowing; recurrent stomach pain and indigestion; blood in your vomit or stools; lactose or sucrose intolerance; persistent diarrhoea; severe liver problems; or osteoporosis.

Pregnancy and breastfeeding

Speak to your doctor before using this medication if you are pregnant, planning on becoming pregnant or breastfeeding.

Driving and using machinery

Potential side effects of Losec include dizziness and sight disturbances. If you are affected by these, do not drive or use machines.

Sucrose and lactose intolerance

Losec tablets contains sucrose, and Losec capsules contain lactose. If you have any sugar intolerances, let your prescriber know.

Page last reviewed:  31/08/2020
Please read the patient information leaflet for this medicine fully before use:

Losec Capsules 10mg

Losec Capsules 20mg

Losec Mups 10mg

Losec Mups 20mg

Losec Mups 40mg


Can I still drink alcohol?

It is not thought that alcohol will affect the way this treatment works directly, but drinking large amounts can increase the severity of gastric reflux symptoms. We would therefore recommend that you do not drink alcohol while using it, or do so only in very strict moderation.

Will I still be able to drive?

Yes. Your ability to drive should not be compromised by the use of this item. But, should you notice any side effects which may make it unsafe to drive, avoid doing so and let your doctor know as a matter of urgency.

Can I take the medicine while pregnant?

Tell your prescriber during consultation if you are pregnant or breastfeeding, as they may wish to advise an alternative form of treatment.

How should I store it?

In a safe environment, away from direct sunlight or sources of moisture, below 30°C.

Am I allergic to anything in the medicine?

The components of Losec Capsules are: omeprazole, disodium phosphate dihydrate, hydroxypropylcellulose, hypromellose, lactose anhydrous, magnesium stearate, mannitol, methacrylic acid – ethyl acrylate copolymer (1:1) dispersion 30 per cent, cellulose microcrystalline, macrogol (polyethylene glycol 400), sodium laurilsulfate, iron oxide E172, titanium dioxide E171, gelatine, printing ink (containing shellac, ammonia, potassium hydroxide, black iron oxide (E172), silica colloidal anhydrous and paraffin liquid.

Contained in Losec MUPS tablets are the following ingredients: omeprazole, cellulose microcrystalline, glycerol monostearate 40-55, hydroxypropylcellulose, hypromellose, magnesium stearate, methacrylic acid – ethyl acrylate copolymer (1:1) dispersion 30 per cent, sugar spheres, synthetic paraffin (NF), macrogol (polyethylene glycol 6000), polysorbate 80, crospovidone, sodium hydroxide (for pH-adjustment), sodium stearyl fumarate, talc, triethyl citrate, iron oxide E172, and titanium dioxide E171.

Do not take these items if you are allergic to any of the above substances.

Is it available over-the-counter?

Losec is only available to buy in the UK with a prescription from a doctor. This can be obtained by completing our simple online questionnaire.

Is it right for me?

See your doctor in person if you are having heartburn symptoms for the first time, or if you think your heartburn symptoms are getting worse. They will be able to assess your symptoms and go through suitable treatment options with you.

If you’re looking to renew your Losec prescription online, take our medical assessment. It only takes a couple of minutes, and your answers will be reviewed by a qualified physician. Approved orders are dispensed and dispatched by our UK-based pharmacy. Delivery on all items is made via 24-hour secure courier.


Page last reviewed:  31/08/2020 is rated 4.9 out of 5 by 3131 customers on TrustPilot!
A simple process
Getting the treatment you need has never been easier with our speedy and simple online service.
  • Search for your medicine

    Find the treatment you need.
  • Fill in a simple questionnaire

    A GMC-registered doctor or a pharmacy prescriber will review your answers.
  • 24h delivery to your door

    Next-day delivery. Every order is sent by tracked courier.
  • Repeat ordering is easy

    We keep your details secure so you can reorder with ease.

No matches found. You can find all our treatments here