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Lisinopril is a tablet medication indicated for high blood pressure. It is the generic version of the drug called Zestril.

PLEASE NOTE: As this treatment is a generic medicine, the brand of the product you receive may be different to the one shown in the picture.

Our prescription renewal facility enables you to buy Lisinopril online. Click ‘buy now’ to start your consultation, and your case will be reviewed by our doctor. Medications are dispensed at our UK pharmacy and shipped by tracked parcel.

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PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.

This content was reviewed by a clinician on

26 April 2022
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 26 April 2022
Product information

Lisinopril belongs to the ACE inhibitor category of drugs, and is used in the treatment of high blood pressure. It is the generic version of Zestril, containing the same ingredient (lisinopril) and is manufactured by a number of companies, including Accord. It is a simple product to administrate, issued as a one a day oral tablet.

  1. Effective at lowering blood pressure
  2. Reduces risk of associated illness
  3. Simple one a day dose

What is Lisinopril? 

Lisinopril is a type of drug which works by decreasing blood pressure in blood vessels. As an ACE inhibitor, it does this by limiting the function of an enzyme in the body. ACE transforms a hormone called angiotensin into angiotensin II, and it is this latter-stage compound which is responsible for causing blood vessels to tighten up. In blocking this conversion, the treatment eases vessel tension and helps to lower blood pressure.

Lisinopril is a generic drug, which means that it is made by a variety of manufacturers.

If you have high blood pressure, you doctor will usually monitor your condition through regular testing, and issue or adjust your treatment as required.

What do Lisinopril tablets treat?

High blood pressure is thought to affect more than one in four people in the UK. It is measured via a gauge, which uses a mercury-propelled millimetre-marked tube. The readings provided by this device are thereby given as millimetre by mercury figures.

Put simply, this device will supply two numbers when measuring blood pressure. The first is called systolic pressure, and gauges the pressure of your blood as it is exported from the heart during a beat. The second, diastolic pressure, measures the pressure present between beats, giving an indication of the resisting quality of the arteries. A blood pressure reading will usually be written or spoken as, for example, 120 over 80. This means that systolic pressure is 120, and diastolic pressure is 80. High blood pressure is characterised by two separate readings of 140 over 90, or higher.

What causes high blood pressure?

People with the condition may not realise that they have it, as it does not always produce directly visible symptoms. But those who are overweight, consume large amounts of caffeine or alcohol, have a very salty diet, smoke or are not physically active have a higher risk of getting it. It is also more common in later life, particularly in those who are 65 and over.

If measures are not taken to combat high blood pressure, it can lead to more serious illness, such as arterial problems, heart disease, and kidney failure. First, addressing any lifestyle habits which may act as contributing factors can help. Your doctor may suggest cutting back on the amount of alcohol you drink, giving up smoking, altering your diet, and undertaking a programme of light exercise.

Those who are not able to reduce their blood pressure through the above methods alone may be advised by a doctor to embark on a course of prescription medicine.

Can I buy Lisinopril online?

Patients who are already taking Lisinopril can renew their prescription and buy online through our secure pharmacy platform. Take our questionnaire, and one of our GMC registered doctors will assess your case. Once they have issued your prescription, your medication will be dispensed at our pharmacy and shipped to your chosen address by special next-day delivery.

Page last reviewed:  26/04/2022


Following the administration instructions issued by your prescriber is essential in getting the most out of your treatment. To reduce the chances of side effects, you should also make sure you read and understand those directions provided in the patient information leaflet prior to use.

  1. Take the tablets as specified by your doctor.
  2. In most instances, the starting dose will be 10mg per day.
  3. A doctor may adjust this to a maintenance dose of 20mg, or higher, after a period of use.
  4. The maximum daily dose is 80mg. 
  5. This may be different if you are starting treatment following heart failure or a cardiac event.
  6. Swallow your tablet whole with water, and try to take it at the same each day.
  7. Your prescriber may advise you to wait and phase your dose in after a specified duration if you are currently using diuretics.
  8. Do not exceed the amount you have been directed to take by your doctor.
  9. If you forget to take it, skip the dose you have missed and carry on the course as normal.

This is only a summary of the directions you will need to adhere to when applying this medication. For more detailed guidance, consult the leaflet provided or ask your doctor or pharmacist.

Page last reviewed:  26/04/2022
Please read the patient information leaflet for this medicine fully before use:

Lisinopril 2.5mg

Lisinopril 5mg

Lisinopril 10mg

Lisinopril 20mg

Side effects & Warnings

Side effects

Side effects

It is important to know about the potential side effects your treatment may cause prior to use, as some of them may require you to stop taking it and seek urgent medical attention.

Go to your nearest doctor or hospital if you experience the following: jaundice; dizziness; increased liver enzymes shown by a blood test; or any indications of an allergic reaction.

Your doctor also needs to know if you notice any other side effects.

Common (1 in 10 people or less):

Headache, dizziness, low blood pressure, coughing, diarrhoea, feeling or being sick, or loss of kidney function.

Uncommon (1 in 100 people or less):

Mood swings, tingling, spinning sensation, taste disturbance, sleep disorder, heart attack, stroke, palpitations, pain, numbness, coldness or blueness in the fingers, runny nose, stomach pain, indigestion, reduced sexual potency in men, tiredness, weakness, rash, dizziness when standing up, or itching.

Rare (1 in 1,000 people or less):

Fall in haemoglobin, mental confusion, dry mouth, hives, hair loss, psoriasis, kidney failure, gynaecomastia, rise in blood levels of bilirubin, lowered levels of sodium in the blood, or syndrome of inappropriate antidiuretic hormone secretion.

This is only a brief summary of the side effects associated with this item. Refer to the leaflet supplied for more detailed information.


Taking it with other medicines

It may not be suitable for use in conjunction with other treatments, as they may interfere with its function or vice versa. Let your doctor know if you are using any other medicinal products, including the following: diuretics; potassium-sparing diuretics such as spironolactone, triamterene or amiloride; anaesthetics; lithium; nonsteroidal anti-inflammatory drugs; allopurinol; tricyclic antidepressants; diabetic tablets and insulin; nitrates or vasodilators such as hydralazine; gold; angiotensin II receptor blockers; aliskiren; muscle relaxants; antipsychotics; other drugs for blood pressure; or sympathomimetics.

Conditions to look out for

Tell our doctor when undergoing consultation if you have any allergies or medical conditions. Do not use this tablet if you have diabetes or kidney dysfunction and are currently using aliskiren.

It may also not be suitable for use in or require special administration by those who have or have had any of the following: dehydration due to sickness and diarrhoea; ischaemic heart disease; heart failure; narrowing of the opening of the aortic or mitral valve; enlarged heart; a heart attack and have low blood pressure; cardiogenic shock; reduced kidney function; renovascular hypertension; dialysis; a kidney transplant; treatment to lessen your reactions to bee or wasp stings; surgery on your airways; any condition affecting the function of the immune system; or diabetes. Please also inform your doctor during consultation if you are Afro-Caribbean, as the dose of Lisinopril issued may need to be adjusted to account for a reduced response.

Pregnancy and breastfeeding

The medicine is not recommended for use during the first three months of pregnancy, and must not be taken by anyone who is three or more months pregnant. Talk to your doctor about alternative treatment options if this applies to you, or if you are trying to have a baby.

Lisinopril is not recommended for use during breastfeeding. Speak to your doctor about different treatments if this applies to you.

Driving and using machinery

This product may cause dizziness. If you have not taken this medicine before and are unsure how it may affect you, do not drive or operate machinery until you are certain.

Please read the ‘what you need to know’ section in the patient information leaflet fully before use.

Page last reviewed:  26/04/2022
Please read the patient information leaflet for this medicine fully before use:

Lisinopril 2.5mg

Lisinopril 5mg

Lisinopril 10mg

Lisinopril 20mg


Can I still drink alcohol?

It is not recommended that you drink excessive amounts of alcohol when using this drug, as it may negate its effectiveness.

Will I still be able to drive?

Yes, provided you experience no side effects which could make doing so dangerous. If you do, then do not drive and speak to your doctor as soon as possible.

Can I take the medicine while pregnant?

It is not recommended that you use these tablets during the first three months of pregnancy, and they should absolutely not be used if you are more than three months pregnant. If you become pregnant while taking them, let your doctor know. They will likely cease treatment with this product, and suggest an alternative.

Lisinopril is also not recommended for those who are breastfeeding, and again, a doctor may choose to issue different medication.

How should I store it?

It should be kept in a safe place, below 25°C.

Am I allergic to anything in the medicine?

This item contains the following ingredients: lisinopril dihydrate, mannitol (E421), calcium hydrogen phosphate dihydrate (E341), pregelatinised maize starch, croscarmellose sodium, magnesium stearate and iron oxide (E172). Do not take it if you are allergic or unable to tolerate any of these components.

Is it available over-the-counter?

No. This treatment is prescription only.

Is it right for me?

Talk to your doctor to find out more about the treatments available. They will initiate a prescription for the most suitable following consultation and a regular review.

To renew your prescription for this medicine and buy Lisinopril online, fill in our medical questionnaire to begin your consultation. Once our doctor has reviewed your case, they will issue a prescription where suitable, and send this to our dispensing pharmacy. We’ll dispatch your medication by special delivery, so you can track your parcel. In most cases, you’ll receive your order in one working day.

Page last reviewed:  26/04/2022
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