Livial is a pill marketed by Merck Sharp and Dohme, used in hormone replacement therapy. It is employed to relieve symptoms of the menopause.
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Livial is a special type of hormone replacement therapy, and is marketed for purchase in the UK by the company Merck Sharp and Dohme. It is effective in relieving common symptoms associated with the menopause, and is also adept at preventing the onset of osteoporosis. This product works differently to other HRT tablets, as it contains a single agent called tibolone which, when dissected by the body, releases three types of hormone. These work in a similar way to oestrogen, progesterone and testosterone.
- Continuous HRT tablet
- Easy to follow course
- Made by a popular brand
The menopause is a natural part of getting older, and is something which every woman goes through at some point in their lives. It most commonly occurs between the ages of 45 and 55, although it can happen earlier in some cases. It is where the body stops undertaking certain processes in preparation for pregnancy, such as ovulation, and menstruation. As a result, the production of an egg by the ovaries, and periodic bleeding, will both at first begin to slow down, before eventually ceasing completely.
When the body embarks on this change, however, certain symptoms can also come about in response to a drop in hormone production. These may include an increase in the instance of headaches, hot flushes, night sweats, mood swings, insomnia, and vaginal dryness. Postmenopause, bones can also become weak and brittle, and more prone to osteoporosis.
Whereas many women going through the menopause will experience these effects to a certain extent, most cases will be mild enough not to warrant treatment. But, those who find that these symptoms are affecting them more than they would like may be able to find relief via hormone replacement therapy.
There are several different types of HRT. Some only contain oestrogen, and these are indicated for use in cases where the user has had their uterus surgically removed. The synthetic version of oestrogen supplied augments natural levels in the body, and reduces symptoms caused by the deficiency of this hormone. Combined HRT, which also contains progesterone, is provided when a person has not had surgery on the womb. This is because oestrogen, when left unopposed, can sometimes rise to excessive levels, and cause the endometrial lining to build up so much that it poses a risk of cancer. Progesterone helps to maintain hormonal equilibrium, and prevent oestrogen levels from reaching potentially unsafe heights.
Livial is a tablet which provides a continuous form of combined HRT, which should only be used once the prospective user has gone for at least 12 months without having a menstrual bleed. It contains an active constituent called tibolone, which disperses into three hormones in the body: oestrogen, progesterone and testosterone. The first two of these hormones serve the purposes described above. However, testosterone is less commonly found in pills of this type.
This is because the reduction of testosterone in the body which occurs during the menopause can also lead to certain symptoms, such as loss of libido and mood swings. Testosterone is also supplied in this treatment to further limit these effects.
Renewing your regular prescription for this item online is simple. You can buy Livial from our UK pharmacy with just a few simple clicks. It only takes a matter of minutes to fill in our medical assessment. Once complete, your responses will be examined by one of our practising doctors. If your order is approved, an electronic prescription will be drawn up for you and sent directly to our GPhC-registered dispensing centre. Your medicine will then be shipped by our secure courier partners.
Prior to using this drug, you should make sure you have read and understood both the directions issued by your prescriber, and the manufacturer’s instructions. This is imperative in keeping the risk of side effects to a minimum, and ensuring that the treatment is as effective as possible.
- Take this medication as prescribed by your consultant.
- Unless otherwise specified, this will be one tablet, once a day.
- Take these tablets at the same each day.
- Swallow whole with water.
- A guide on when to begin using Livial can be found in the leaflet. Refer to this before use.
- Do not make up for a forgotten dose with a double dose. If you forget to take your pill, you can do so when you remember, provided no more than 12 hours have passed since your scheduled dose. If a period of 12 hours or more has elapsed, you should leave the missed dose and continue the course as normal.
The above is provided only as a brief guide. Do not use this product without first familiarising yourself with the more detailed instructions in the patient information leaflet.
Download Livial patient information leaflet
It is vital to be aware of the side effects this drug may induce, as some may necessitate urgent medical attention. Let your doctor know right away if you notice any indications of: a rise in blood pressure; jaundice; a first-time migraine or one which is worse than normal; a blood clot; or an allergic reaction.
Common (1 in 10 women or less):
Breast, stomach or pelvic pain, excess hair growth on the face or body, breakthrough bleeding or spotting, increased vaginal secretions, itching, irritation and thrush, excessive growth of the womb lining, or weight fluctuations.
Uncommon (1 in 100 women or less):
Swollen hands, ankles or feet, acne, or vaginal infections.
Rare 1 in 1,000 women or less):
The side effects listed here are only a summary. Please refer to the patient information leaflet for a more detailed account.
Taking it with other medicines
Inform your prescriber of any other treatments you are currently using when undergoing consultation for this product. Livial may interact with: blood-thinning agents such as warfarin; epilepsy drugs including phenobarbital, phenytoin and carbamazepin; rifampicin; or St John’s Wort.
Conditions to look out for
Tell your doctor if you have a history of any medical conditions when completing our online health assessment. You should not use Livial if you have or have ever had: breast cancer or other type of cancer which is responsive to oestrogens; any episodes of unexplained vaginal bleeding; a blood clot in a vein; blood clotting disorders; endometrial hyperplasia; a heart attack, stroke or angina; lactose intolerance; any liver disease which is still causing abnormal function test; or porphyria.
If you have or have ever had the following conditions, special care may need to be taken when using this treatment: fibroids inside the womb; endometriosis; endometrial hyperplasia; an increased susceptibility to blood clots or oestrogen-sensitive cancer; high blood pressure; gallstones; liver disorder; diabetes; migraine; lupus; epilepsy; asthma; otosclerosis; high triglycerides; or cardiac or kidney-induced fluid retention.
Your GP will need to monitor your HRT. When you are taking this treatment, it is important to have regular consultations with them, at least once a year.
HRT and cancer
More information on HRT and cancer risk can be found in the leaflet provided.
Pregnancy and breastfeeding
This medication is for postmenopausal use only. It should not be used during pregnancy or breastfeeding. If you get pregnant, you should stop taking it and let your doctor know.
Driving and using machinery
Livial should not influence your capacity to drive or use machines.
Livial contains lactose. If you are intolerant to some sugars, make sure to tell your prescriber during consultation.
Can I still drink alcohol?
Yes. It is unlikely that alcohol will interfere with the way Livial works.
Will I still be able to drive?
Yes. Your capacity to drive should not be reduced by the use of this item. However, some associated side effects may make driving unsafe, and if you experience any of these, you should avoid driving and talk to your doctor.
Can I take the medicine while pregnant?
No. It should not be used by anyone who is pregnant or trying for a baby, or is breastfeeding.
How should I store it?
In a safe environment, below 25°C, out of the reach of children. Store in the pack to protect from exposure to light and moisture.
Am I allergic to anything in the medicine?
This product contains the following ingredients: tibolone, potato starch, lactose, ascorbyl palmitate and magnesium stearate. If you are allergic to any of these components, do not use it.
Is it available over-the-counter?
A prescription is required before the purchase of Livial can be made in the UK. Our doctor will only draw up a prescription for you if, after reviewing your case, they are satisfied that this drug is suitable for you to use.
Is it right for me?
Which menopause therapy you use will be determined by your GP. During your periodic review with them, they will discuss options with you and initiate a prescription for treatment as appropriate.
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