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ReQuip is used to treat restless legs syndrome (RLS). The active ingredient ropinirole works to increase dopamine levels in the brain and improve RLS symptoms. 

Our online pharmacy service makes it easy for you to get your ReQuip prescription renewed and buy your treatment. Complete our questionnaire and your order could be with you by tomorrow. 

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This content was reviewed by a clinician on

14 March 2021
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 14 March 2021
Product information

ReQuip is a branded medication used in the treatment of restless legs syndrome (RLS). The active ingredient is ropinirole hydrochloride which is a dopamine agonist. It works on the brain to help restore dopamine levels in order to control the symptoms associated with RLS. 

Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a condition of the nervous system and can cause an uncontrollable urge to move the legs, often associated with an unpleasant creeping feeling in the area. The severity of the condition can vary greatly. For some people it can be a mild sensation that only occurs occasionally, however, others have to deal with the symptoms on a daily basis to the point where it impacts their usual daily routine. 

It is not entirely understood why RLS occurs and it can develop in anyone at any age. However, it is most commonly diagnosed in women. It is thought that genes may play a part because the condition can be seen to run in families. RLS can also develop as a secondary symptom to another condition or as a side effect to certain medications. Medications used to treat diabetes, depression, nausea and iron deficiency can sometimes cause RLS. 

In order for ReQuip to effectively treat the symptoms of RLS, you may be required to start on a low dose and gradually build up to a maintenance dose. It may take some time in order to establish the best dose for your symptoms. 

You may be advised to also try some lifestyle changes to help improve your symptoms. This could include quitting smoking if you are a smoker, taking regular exercise, following a regular sleeping pattern and avoiding stimulants such as caffeine and alcohol. You may be able to help reduce the severity of an RLS flare up by massaging the area, stretching the muscle, going for a walk, using a hot or cold compress or trying to distract yourself with a task. 

RLS cannot be cured but symptoms can be successfully managed with medication. ReQuip uses the active ingredient ropinirole hydrochloride to increase dopamine levels in the brain. Those with RLS are often found to have low levels of dopamine. Therefore as ReQuip begins to restore dopamine levels, the symptoms of RLS should decrease. 

If you are experiencing symptoms of RLS for the first time, you should arrange an appointment with your GP. 

If you are looking to renew your ReQuip prescription, you can do so via our online pharmacy service. Complete our simple medical questionnaire and your order will be reviewed by a doctor. Approved orders are dispensed by our UK-based pharmacy and shipped directly to you by next-day courier. 

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Page last reviewed:  14/03/2021

Follow the instructions given by your doctor. Doing so can help make sure that the medicine works as well as it should and also reduce the chances of unwanted side effects. 

  1. Take as directed.
  2. It can take some time to reach the correct dose to help treat your symptoms.
  3. Your doctor will help decide how much you should start off taking. Your doctor may increase your dosage over time.
  4. Swallow your tablets whole, with a glass of water.
  5. It is also a good idea to take your tablets with food as this can help prevent feelings of nausea.
  6. If you forget to take a dose, do not double up. Just take the next dose as normal.
  7. However, if you miss several doses you may need to speak to your doctor to decide how to start taking ReQuip again.
  8. Do not suddenly stop taking ReQuip. Doing so can exacerbate symptoms and cause other serious health problems.

For further help and information on ReQuip, please read through the patient leaflet enclosed with your treatment.

Page last reviewed:  14/03/2021
Please read the patient information leaflet for this medicine fully before use:
Side effects

ReQuip, like any other medication, can cause side effects. If you develop symptoms of an allergic reaction, you should seek medical attention immediately. 

Very common (1 in 10 people or more):

Nausea, fainting, drowsiness. 

Common (1 in 10 people or less):

Hallucinations, vomiting, feeling dizzy, heartburn, stomach pain, swelling of the legs, feet or hands.

Uncommon (1 in 100 people or less):

Feeling dizzy or faint, feeling very sleepy during the day, falling asleep very suddenly without feeling sleepy first, mental problems such as delirium, delusions or paranoia.

Frequency unknown:

Allergic reactions such as hives, swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing, rash or intense itching; aggression; excessive use of ReQuip (craving for large doses of dopaminergic drugs in excess of that required to control motor symptoms, known as dopamine dysregulation syndrome); depression; apathy; anxiety; lack of energy, sweating or pain may occur (called dopamine agonist withdrawal syndrome or DAWS) after stopping or reducing your Requip treatment;  changes in liver function, which have shown up in blood tests

Please refer to the patient information leaflet for more details on the possible side effects. 

Taking it with other medicines

It is important that our doctors are made aware of any medications, herbal remedies or supplements you are currently taking or have recently taken. If ReQuip is taken alongside some other medications it can alter its efficacy. 

Please inform our doctors if you are taking the antidepressant fluvoxamine; HRT (hormone replacement therapy); the antibiotics ciprofloxacin or enoxacin; medication for other mental health problems, such as sulpiride; metoclopramide, which is used to treat nausea and heartburn; cimetidine, used in the treatment of stomach ulcers and any other medicine for Parkinson’s disease.

Conditions to look out for

Inform the doctor or pharmacist if you currently have or have had in the past any of the following conditions: liver disease; kidney disease; mental health problems; heart problems or unusual compulsive behaviour.  

Pregnancy and breastfeeding

ReQuip is not recommended during pregnancy or when breastfeeding. Speak to your doctor for advice if this applies to you. 

Driving and using machinery

This medication can make you feel drowsy or suddenly extremely sleepy. If this happens to you, you should avoid driving or operating machinery. Speak to your doctor if this could cause problems for you. 

Food, drink and alcohol

Taking ReQuip with food can help make you less likely to feel sick. 

You should not drink alcohol when taking ReQuip.

Lactose intolerance

ReQuip contains lactose. Inform the prescriber if you are lactose intolerant. 

Page last reviewed:  14/03/2021
Please read the patient information leaflet for this medicine fully before use:

Can I still drink alcohol?

No. Do not drink alcohol when taking ReQuip. 

Will I still be able to drive?

This medicine can cause side effects that may impact your ability to drive. This includes drowsiness and extreme or sudden sleepiness. Should you notice these side effects, speak to your doctor and do not drive or operate machinery. 

Can I take the medicine while pregnant?

Discuss your treatment with your doctor if you are pregnant, trying to conceive or are breastfeeding. 

How should I store it?

Keep away from children and in a cool environment. 

Am I allergic to anything in the medicine?

ReQuip contains the following ingredients: ropinirole hydrochloride, lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium

Stearate. The film coating on each dosage contains a combination of hypromellose, macrogol 400, titanium dioxide (E171), polysorbate 80 (E433), iron oxide yellow (E172), indigo carmine aluminium (E132) or iron oxide red (E172). 

Do not use this product if you have an allergy to any ingredients that are found in it.

Is it available over-the-counter?

No. This treatment requires a prescription. 

How can I buy ReQuip online?

You can easily buy your ReQuip treatment through our online pharmacy service. Simply fill out a medical questionnaire for one of our clinicians to review. Approved orders are then sent to our UK pharmacy to be dispensed. All orders are shipped by next-day courier. 

Page last reviewed:  14/03/2021 is rated 4.9 out of 5 by 3131 customers on TrustPilot!
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