- Solifenacin Succinate
- Solifenacin Succinate
Vesicare is a treatment for urinary incontinence, made by Astellas. It acts on receptors which control muscles around the bladder, reducing pressure and the need to frequently urinate.
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The standard dose is one tablet, containing 5mg of solifenacin succinate, taken once a day for a specified period. This may be increased to two tablets if necessary.
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Vesicare is a tablet medication, indicated for urinary incontinence. It is taken once a day, and helps to reduce symptoms by relaxing the muscles situated around the bladder. Manufactured by Astellas, the active constituent in Vesicare is an antimuscarinic called solifenacin succinate.
Urinary incontinence, also referred to as UI, is a condition characterised by the involuntary leaking of urine from the bladder.
The nature of the condition can make it a difficult subject for many to talk about openly. But it is worth noting that urinary incontinence is very common. The NHS projects the number of people in the UK affected at somewhere between 3 and 6 million. It is also thought that one in three women will experience urinary incontinence at least once in throughout their lives.
There are two main types.
One is stress incontinence (sometimes known as SUI). This happens when the pressure on the bladder exceeds the strength of the muscle which keeps urine from seeping out, also known as the urethral sphincter. This might be because the urethral sphincter has become weak or damaged, for instance due to childbirth, or following a surgical procedure. Other factors which may compound the issue are obesity, or a condition affecting the spasming of muscles, as these can increase pressure on the bladder.
As a result, someone with stress incontinence may notice the leakage of urine more when they laugh, sneeze, cough, or experience any other muscular contraction which affects the area surrounding the urinary tract.
Another type of urinary incontinence is urge incontinence, also known as UUI. This is also known as an overactive bladder. This causes the bladder muscles to contract with excess force, and in turn creates a sudden and urgent need to urinate, and may lead to involuntary loss of urine.
Sometimes urge incontinence can be a sign of an underlying problem, so it is important to have your case checked by a doctor in person if you experiencing them for the first time.
There are several therapy options for those with an overactive bladder. Certain training motions, such as kegel exercises, can help to reduce symptoms by strengthening certain muscles that help to stop urine from leaking. Other behavioural techniques, such as avoiding drinking fluids before bed and cutting down on caffeine, may also help. However, where these measures alone fail to provide relief, medication may be recommended.
Vesicare provides an effective solution for those who have an overactive bladder. The treatment is an anticholinergic, and contains an active ingredient called solifenacin succinate. This works by helping muscarinic receptors in the muscles which line the bladder to block out signals which cause them to tense up. Vesicare thereby reduces the effect of an overactive bladder by relaxing its muscular wall lining.
We provide this medication only to patients who are already using it on prescription under the guidance of their doctor. If you have symptoms of UI which have not been checked by a doctor, you should see your GP in person.
You can renew your prescription and buy Vesicare from our UK pharmacy by taking our short questionnaire. It only takes two to five minutes to complete on average, and the answers you provide are kept confidential. This enables one of our practising doctors to review your case, and if suitable, draw up a prescription. Orders are fulfilled by our dispensing pharmacy before being shipped by tracked parcel.Buy now
How to use Vesicare
It is vital to follow the directions issued by your prescribing doctor, to ensure that you get the best possible results from your medicine. Observing the guidelines set out in the patient information leaflet will also assist you in restricting the possibility of side effects.
- Take Vesicare as prescribed by your doctor.
- For most cases of Urinary Incontinence, this may be one tablet per day for a specified period.
- In some instances, your doctor may suggest a higher dose and prescribe two tablets per day.
- Swallow the tablets whole, and take them with water.
- Do not take more than the amount your doctor has instructed.
- If you miss a dose, carry on with the course as normal. Do not take more than one dose in any one day.
More detailed information can be sourced in the leaflet supplied with the product.
Vesicare side effects
Even though not everyone gets them, it is still important to be aware of the side effects your medication may cause, so that you can seek medical advice if necessary. Tell your doctor right away if you notice any signs of an allergic reaction, or anything else which causes you concern.
Very common (1 in 10 people or more):
Common (1 in 10 people or less):
Blurred vision, constipation, feeling sick, indigestion or stomach discomfort.
Uncommon (1 in 100 people or less):
Urinary tract infection, drowsiness, gastric reflux, dry eyes or nasal passages or difficulty passing urine.
Rare (1 in 1,000 people or less):
Hard stool blockage in the large intestine, urinary retention, dizziness, headache, being sick, chest pain, abnormal heart rhythm, itching or rash.
Very rare (1 in 10,000 people or less):
Hallucinations or confusion.
This is not a complete account of the possible side effects which this product may induce. More details can be found in the patient information leaflet.
Taking it with other medicines
Inform your prescriber if you are taking other treatments, as these may cause Vesicare to be less effective, or vice versa. This product may interact with the following, or cause the risk of side effects to be greater: other anticholinergic medicines; cholinergics; digestant aids like metoclopramide and cisapride; ketoconazole, ritonavir, nelfinavir, itraconazole, verapamil and diltiazem; rifampicin, phenytoin and carbamazepine; or bisphosphonates.
Conditions to look out for
Some people may not be able to use this drug if they have certain conditions. You should not use it if you have a history of: abnormal heart rhythm or heart disease; urinary retention; a severe stomach or bowel condition; myasthenia gravis; glaucoma; treatment with kidney dialysis; or severe liver or kidney disease. You may also not be able to use it if you have or have ever had: a bladder obstruction; constipation; liver disease; a hiatus hernia; or a nervous disorder.
Pregnancy and breastfeeding
Check with your doctor. Vesicare must not be used during breastfeeding. Use during pregnancy is not recommended unless deemed absolutely necessary by your doctor.
Driving and using machinery
This medication may cause vision and concentration problems. If these side effects occur, do not drive or use machines.
Vesicare contains lactose. Tell your prescriber if you have any intolerances to sugars.
Q&A: our Vesicare discussion forum
Can I still drink alcohol?
Alcohol will likely not cause interactions with this drug. However, you should only drink alcohol in moderate amounts, as excessive levels of consumption may make UI symptoms worse.
Will I still be able to drive?
Yes, but only if you experience no significant side effects. If you feel as though your ability to drive may be compromised, do not drive and consult your doctor.
Can I take the medicine while pregnant?
Only take Vesicare if are pregnant or breastfeeding if your doctor thinks you need it.
How should I store it?
Keep at room temperature, in a safe place out of the reach of children.
Am I allergic to anything in the medicine?
This drug contains: solifenacin succinate, maize starch, lactose, hypromellose (E464), magnesium stearate, macrogol, talc, titanium dioxide (E171) and iron oxide (E172). Do not use if you are or think you may be allergic to any of these constituents.
Is it available over-the-counter?
You can only buy Vesicare in the UK if you have a prescription, as a doctor will need to check your suitability prior to use. We only offer this item on a prescription renewal basis. The answers you provide to our medical survey will be used to assess whether or not this drug is safe for you, and if it is, our practitioner will draw up a prescription and send it to our pharmacy on your behalf.
Is it right for me?
If you are experiencing urinary incontinence symptoms, you should see your doctor. They will be able to examine the possible causes, and issue appropriate treatment where required.
You can renew your Vesicare prescription in a matter of minutes by taking our health questionnaire. Once our doctor has reviewed your case and approved your items, your order will be passed on to our dispensing pharmacy. Based in the UK, our pharmacy only ever ships orders by tracked, express delivery, so that you can begin using your treatment the very next working day.
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