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Erectile dysfunction

Erectile dysfunction (‘ED’) is a sexual health issue which is common in older men, though it can affect young men too. Also called impotence, it’s thought to impact at least 50% of men later in life. 

  1. 70% of men never seek advice for sex-related conditions
  2. Treat erection problems discreetly
  3. Branded ED treatments, various strengths and doses

Our UK-based pharmacy stocks well-known ED treatments such as Viagra, as well as other brands like Levitra. Take a short questionnaire and, pending approval from a registered member of our medical team, your order will be shipped and tracked in discreet packaging.

  • UK prescribers
  • 24 hour delivery
  • Secured payment

14 product result(s) for Erectile dysfunction

ED Trial Pack

ED Trial Pack

  1. Ideal for first time users
  2. Sample different treatments to find the one that works best
  3. Generic and branded packs available
Viagra Connect

Viagra Connect

  1. Pharmacy medicine for erectile dysfunction
  2. Usually gets to work in 30-60 minutes
  3. Effective for up to 5 hours


  1. Effective from just 30 minutes
  2. Well-known treatment for erectile dysfunction
  3. Branded medication made by Pfizer


  1. Starts to work from 30 minutes
  2. Remain active for 5 hours
  3. Effective, cheaper alternative to Viagra


  1. Weekend pill lasts for 36 hours
  2. Daily option available
  3. Enjoy sex with no interruptions



  1. Generic version of Cialis
  2. Bioequivalent and works in the same way
  3. Weekend or daily pills available


  1. Easy-to-take single tablet.
  2. Works in just 15-30 minutes.
  3. Can produce effects for up to 5 hours afterwards.


  1. Suitable for men over 50 years old
  2. Active for up to 5 hours
  3. Regular or orodispersible tablets available


  1. Generic alternative to Levitra
  2. Oral treatment for erectile dysfunction
  3. Available in three doses


  1. Begins to work within 10 minutes
  2. Urethral suppository
  3. Erections last for between 30 and 60 minutes


  1. Noticeable differences in as little as 5 minutes
  2. Available in two forms
  3. Simple to use injections
Vitaros Cream

Vitaros Cream

  1. Non-invasive method of treatment
  2. Effective in 5-30 minutes
  3. Suitable for users who can’t take tablets


  1. Administered directly into the penis
  2. One dose works for up to an hour
  3. Sometimes prescribed when other ED treatments haven’t worked
Viridal Duo

Viridal Duo

  1. Injection treatment for ED
  2. Available in three doses
  3. Simple to use
Notify Me


  1. Topical gel ED treatment
  2. Can produce immediate results
  3. Potentially fewer side effects


  1. Easy to swallow, chewable pill
  2. Gets to work in 30-60 minutes
  3. Different doses available

Of erection problems, impotence is by far the most common. A lot of people think it only affects older men, which it is more likely to, but it can happen in young men too. 

The rise of popular ED drug Viagra and the birth of the internet as we know it in the 1990s shone a light on large groups of men who had previously not felt comfortable coming forward to discuss their ED symptoms. Since then, we now know how common ED is - said to affect around 1 in 5 men at some stage in their lives. 

What is erectile dysfunction?

Erectile dysfunction is the temporary or permanent inability to get or maintain an erection long enough for sex. It is caused mainly by physical health problems which relate to blood flow and cardiovascular function, and can be a symptom of a broader health condition. 

The most common physical causes of impotence are cardiovascular disease (which can include a spectrum of conditions including HBP, coronary heart disease and stroke), diabetes, hormone problems, medications already being taken, neurological disorders, pelvic injuries or trauma or anatomical abnormalities. 

Many, but not all, of these physical causes of ED can damage and disrupt blood vessels and the flow of blood to the main penile muscles responsible for erections, the corpora cavernosa. 

The physical causes of ED are often the consequence of poor lifestyle choices. Doctors will often recommend simple lifestyle changes to men suffering with moderate ED symptoms, to see if improvements are observed over time. This includes things like drinking a low-risk amount of alcohol each week, not smoking, eating well and exercising regularly.

However, ED isn’t always caused by physical health conditions. Sometimes, but to a lesser extent, it is caused by psychological factors. This can include mental health problems such as depression and anxiety, and commonly performance anxiety (which is the pressure of performing well during sex, which makes it difficult to acheive erections). 

Physical and psychological causes can also feed into each other or both be responsible for the symptoms of ED. So it’s important both of these things are addressed in order for the symptoms of impotence to be fully dealt with. 

What you should know about ED treatments

Ever since the medical community became aware of the prevalence of impotence, more work has been undertaken to understand the condition and develop effective treatments. Sometimes, treating ED can just be a case of adapting the patient’s lifestyle (or doing this in conjunction with the use of other treatment). 

The most well-known medicinal treatments for ED are phosphodiesterase type 5 inhibitors (PDE5is). These became, and have remained, popular since the release of sildenafil in the late 1990s. 

Pfizer, who developed and marketed the first oral ED drug Viagra, no longer possesses the sole rights to produce Sildenafil for ED. Since the patent expired in 2013, other companies have been permitted to produce their own generic versions of Sildenafil. Post Viagra, other branded ED tablets including Cialis and Levitra came to market in 2003, followed by Spedra in 2014. Cialis and Levitra also have their own generic counterparts (tadalafil and vardenafil).'

While these drugs work in the same way, there are some differences in PDE5i ED treatments people should know about. They all take slightly different amounts of time to work in the body, and Cialis can last the longest for up to 36 hours. Some of these drugs, like Levitra for example, are available in relatively small doses to help people with pre-existing health conditions who may already be taking other medicinal treatment. 

All PDE5i drugs are prescription only medications with the exclusion of Viagra Connect, a medium dose ED drug, which became a pharmacy medicine in 2018. 

What different treatments are there for ED?

One of the first treatment options for ED a doctor may recommend are simple lifestyle changes, like cutting out junk food or exercising more. Over time, these things can be effective. 

PDE5i pills and hard oral capsules are the most well-known of ED treatments. These work to dilate blood vessels and increase blood flow. However, they will not work unless the patient is aroused and sexually stimulated. If a man struggles with erections even after taking these drugs, there could be psychological causes at play. Doctors sometimes recommend talking therapy for ED, and it can be an effective treatment option. 

Aside from hard pills for ED, there are also injectable impotence treatments such as Caverject. There are urethral suppositories like MUSE, and creams like Vitaros. 

There are also treatment options that could be of benefit which are not medicinal. These include vacuum constriction pumps, surgically inserted prosthesis or vascular surgery. However, these should be discussed at length with your doctor. 

How to get ED treatment 

If you notice symptoms of erectile dysfunction for the first time, it’s important to discuss these with your own doctor before seeking out ED treatment. This will help to rule out underlying health conditions as causes. 

There are a number of ways to get ED treatment. In the UK, some men can get ED treatment on the NHS. If doctors deem it clinically necessary, they can prescribe sildenafil, generic Viagra, in a number of doses. (Typically, they will start patients on low or medium doses to see how patients respond to treatment). Sildenafil is the most commonly prescribed drug with the NHS, and it is uncommon for brands like Viagra, Cialis and others to be offered in this way. 

Treatments for ED can also be sought out online. However, it’s vital that men suffering with the symptoms of impotence exercise caution when looking online for treatment. There are a number of illicit sellers who trade illegally. Make sure the site you use is UK pharmacy registered with bodies like the MHRA and CQC, is overseen by legitimate registered medical professionals who can offer prescriptions (you need one to get the majority of ED drugs), and that they do not make bogus claims or offer ‘free’ or ‘discounted’ drugs. 

Buying ED medication online is a form of private health treatment, which can also be done in person. Private doctors, urologists and clinics can provide treatment on a private basis, but it tends to be more expensive. 

Only one ED drug can be acquired without a prescription: Viagra Connect (50mg). This can be potentially sought in a number of pharmacy chains and shops including Lloyds, Superdrug and Boots. 

Consult about ED with Treated.com 

Take a questionnaire about your health and symptoms. Your answers will then be reviewed by a member of our registered medical team. They will check over your responses and be in touch if necessary. If approved, you will be prescribed ED treatment. All orders placed before 4pm Monday to Thursday are delivered the very next day, by a third-party courier, and sent in discreet packaging.

Page last reviewed:  26/04/2022
Types of Treatment

Types of Treatment

ED pills are mostly prescription-only medications 

The main classification of ED drugs is known as phosphodiesterase type 5 inhibitors (PDE5is). 

The most well-known impotence treatment, Viagra, is a PDE5i. Also known as the little blue pill, it was discovered accidentally in the early 1990s by pharmaceutical giant Pfizer. 

The drug they were originally testing was called sildenafil citrate, to see if it might treat high blood pressure. A group of male volunteers reported sexual side effects during clinical trials, namely increased erections. Eventually, Pfizer would rebrand the drug Viagra as a treatment for erectile dysfunction. It’s also sold under its generic name, Sildenafil. 

There are other ED tablets as well as Viagra. One of these is Spedra (known in other countries as Stendra). The active ingredient in this treatment is Avanafil, but this is not available as a generic treatment yet. 

Another ED drug is known as Cialis, marketed by pharmaceutical company Lily. Its generic treatment name is Tadalafil. 

The other impotence pill is Levitra, sold under the generic name Vardenafil. This is also available as an orodispersible (dissolvable in the mouth) tablet.

However, there are more ED treatments available besides tablets or hard, oral capsules. These are in a different classification, called ‘prostaglandins’ (or PGE1s), which are sometimes injected into the base of the penis, such as Caverject. 

Another form of prostaglandin is as a urethral suppository, such as MUSE

Prostaglandins are also available as ED creams. These need to be inserted into the urethra with a small plunger, like the impotence treatment Vitaros. 

The vast majority of PDE5i and prostaglandin ED treatments are prescription only medicines. This means a doctor must authorise their use before a patient is able to purchase them. The only exception to this is Viagra Connect, owned and marketed by Pfizer, which became a pharmacy ED drug in the UK in April 2018. 

How do PDE5is work? 

The function of PDE5is is to dilate blood vessels, including those of the penis. This allows for increased blood flow in moments of arousal, which must be present for erections to work, causing stiffness and rigidity. 

Erections begin in the mind, when something is sexually stimulating. The brain seconds chemical messages to the penis, causing muscles here to relax. Two of these muscles are called the corpora cavernosa, which the urethral canal runs just beneath. 

When the corpora cavernosa dilates, blood rushes into the empty pockets of space until the penis becomes filled with blood. Pressure keeps the blood trapped inside, and after climax it is released. 

PDE5i pills ensure that the muscles and blood vessels in the penis can properly dilate. ED can often be caused by circulation problems, so it’s important to see a doctor or urologist if you notice ED symptoms or encounter problems with impotence or the first time. 

How do prostaglandins work? 

Prostaglandins work slightly differently to PDE5 inhibitors. They are hormone-like compounds which work to tell and alert the body of certain things. For example, when you suffer an injury, prostaglandins are responsible for alerting you to it, by sending pain signals to the brain from the affected area.

Erectile dysfunction treatments like Caverject and MUSE (which both contain the active ingredient alprostadil that’s responsible for their function) work to mimic the actions of prostaglandins. Essentially, they allow for greater sensitivity in the regions of the penis. 

Alprostadil enables those vessels letting blood into the penis to dilate; and encourages blood vessels allowing blood to exit the penis to narrow, keeping blood in the penis and helping it to stay erect.

What are the side effects of impotence drugs?

Side effects can vary within medicines of the same class, so it’s important to always read the patient information leaflet provided with your medicine. If you’re unsure, or think you might be experiencing a side effect, it is vital to talk to your doctor or pharmacist immediately.

Not everyone who uses ED treatment gets side effects.

However, there are some common or very common side effects which are consistent across different drug classifications. For example, many PDE5 inhibitor pills share certain common side effects. These can include things like headache, nausea, facial flushing, hot flush or a blocked nose. 

Injectable prostaglandins can have similar side effects too, including other effects such as pain in the penis, or the penis becoming bruised.

Impotence creams can sometimes cause certain common side effects such as burning, itching, rash and general pain in the area of application.

Can I take ED drugs with other medications?

Both PDE5 inhibitors and prostaglandins can interact with a range of different medicines, so it is essential to inform your doctor of any medicines you are currently taking, or illnesses you have previously suffered from. 

Do not start or stop taking any medicines before checking with your doctor or pharmacist first. This includes prescription medicines, non-prescription medicines, and remedies.

Other types of treatment and natural solutions to ED

There are several non-medicinal options available to those who prefer not to take prescription drugs, or have found them to be unsuitable, including: vacuum constriction devices (pumps), prostheses or, in rare cases, surgery.

There are also natural or ‘herbal remedies’ for ED, though their success and effectiveness has been a much debated area in the medical community. Some research shows that they may improve sexual performance, but several other studies posit that they aren’t really any better than a placebo.

Page last reviewed:  26/04/2022
Question and Answers

Who gets erectile dysfunction? 

Impotence becomes more likely with age, and is more commonly observed in men over 40. However, impotence affects young men too. 

Why does erectile dysfunction happen? 

The reasons behind sexual dysfunction in men can often be complex, and sometimes hard to get to the bottom of. Impotence is largely caused by physical factors, but can also be the cause of psychological problems such as performance anxiety. (Or, it can be a combination of both physical and mental factors). 

The main physical causes of ED are often underlying health conditions which impact things like blood flow and vascular function. 

The main psychological causes of ED often impact feelings of sexual stimulation and arousal. So even if the vascular system is healthy, erections are still difficult to achieve. 

Which erectile dysfunction drug works best?

ED drugs work in different ways, depending on the form they take and how they’re administered, but also depending on things like pre-existing health conditions, treatments a person already takes, how they deal with ED drugs and whether they encounter side effects. 

ED can range from moderate and only occasional to very severe, so, similarly, different doses and strengths will be appropriate for different men. 

What’s the difference between the medications?

The main difference between the medications is their method of application, and their duration of function. In addition, some are branded and some are generic.

Oral tablet treatments for impotence, like Viagra, Levitra, Sildenafil or Cialis, are a convenient way of relieving ED symptoms, especially if this is the first time you’re trying the medication. ED tablets typically take at least 30 minutes to work, so would need to be taken in advance of sex.

Non-tablet treatments for impotence include injectables and urethral suppositories. Injections, such as Caverject, are injected into the base of the penis, and work almost immediately.

Alternatively, urethral methods of application, like MUSE, are inserted into the tip of the penis. These tend to work far quicker than oral ED tablets, but are not usually recommended unless you’ve already tried a tablet and found it to be ineffective. 

Should I take Viagra, Cialis, Levitra, or Spedra?

All of these drugs are known as ‘PDE5 inhibitors’, and work in the same way although some get to work faster than others, and some stay active for longer than others.

Viagra typically takes 30-60 minutes to work, and lasts for around 4 hours. (Nipatra and Sildenafil contain the same ingredient, and tend to produce similar results.) Cialis can take one or two hours to work, depending on which dose you use, but can remain active for up to 36 hours afterwards.

Levitra takes 30-60 minutes to have an effect, and stays active for about 5 hours. Spedra is typically the fastest-working tablet treatment, producing results in as little as 15-30 minutes, lasting for around 5 hours.

Which medicine you choose to buy depends on what you've used before, your health, when you feel most comfortable taking the medicine, and how long you want it to last for. All of these medicines should only cause erections when you are sexually aroused.

Is it safe to buy ED drugs online? 

It is safe to buy ED treatments online provided you do so from a genuine, registered pharmacy. We are registered with the MHRA, GPhC and CQC. 

Our service is overseen by GMC-registered doctors and GPhC-pharmacy prescribers. 

All treatments we offer are licensed and authorised for use in the UK. We only issue drugs for ED where clinically is necessary. 

Is ED treatment right for me?

Our simple questionnaire will be able to help our doctor determine whether the medication for ED is suitable for you. After you have completed this, it will be reviewed by one of our qualified GPs or pharmacy prescribers. If approved, a prescription will be generated for you, and you’ll receive your order from our dispensing pharmacy within 24 hours.

Page last reviewed:  26/04/2022

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We promise to keep your details secure and private. We will never sell your information or share it with third parties. Whatever treatment you buy online from us, we will send in plain, unmarked packaging via our secure courier service.

Delivery on all items is included in the price. After your order has been dispatched, you’ll be supplied with a tracking number, allowing you to follow the progress of your items every step of the way. We deliver to anywhere in the UK, so whether you’re in London, Birmingham, Manchester, Glasgow or Cardiff, your order will be at your door within just 24 hours of approval from our doctor.

This content was reviewed by a clinician on

26 April 2022
dr daniel

Dr Daniel Atkinson

(GP Clinical Lead - GMC No. 4624794) 26 April 2022
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