Vaginal gel or oral tablet to ease symptoms.
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Estrace is an estrogen-only treatment to help you with the symptoms of menopause. It comes as an oral tablet or vaginal cream, so you can pick the one that suits your needs.
Our experts will work with you to find the perfect treatment for your needs and for your life. Don’t do menopause alone. We’re here to support you when you get Estrace online.
Estrace is a type of HRT (hormone replacement therapy) available as either a tablet or vaginal cream. Both forms contain the active ingredient estradiol, which is a synthetic estrogen. Although primarily used to treat the symptoms of menopause (like hot flashes, mood changes and vaginal dryness), it can also be used as part of some cancer treatments and to help prevent bone loss (osteoporosis).
Estrace tablets should be taken alongside a progestin if you haven’t had a hysterectomy, and only for as long as it helps your symptoms for. Ideally, your treatment should be reviewed every three-to-six months to see if your dose can be lowered, or to see if treatment can be stopped entirely. Estrace vaginal cream might be safer to use on a more long-term basis because the risks are lower. And it can be used without a progestin, even if you haven’t had a hysterectomy.
Menopause can happen for one of two reasons: either through age, where your body stops producing eggs and you stop getting periods, or through a medical procedure that stops your ovaries from working (called ‘medically induced menopause’). In either case, the amount of estrogen that circulates in your body decreases. This decrease in estrogen is what causes your symptoms. Estrace works to counteract these symptoms by, quite simply, supplying your body with estrogen, making up the deficit.
Another common risk associated with the menopause is decreased bone density, called osteoporosis. Estrace tablets can also help to reduce and prevent this bone loss, though other treatments may be recommended if you have no other symptoms. Similarly, Estrace tablets can help with vaginal symptoms like vaginal dryness, but the vaginal cream will be better for you if this is the main symptom you’re getting.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Make sure to follow the instructions given to you by your doctor when taking Estrace.
Take one tablet a day, with water (your doctor will help you decide the dose that’s right for you)
Swallow it whole — don’t chew or crush it.
Estrace Vaginal Cream comes with an applicator to help you insert it into your vagina.
Estrace comes in either tablets for systemic (whole body) menopause symptoms (like hot flashes and mood changes), or a vaginal cream for local symptoms, like vaginal dryness or atrophy (weakening).
In terms of doses, you can take the tablet as either a 0.5mg, 1mg or 2mg dose. The one you’re prescribed will be the lowest one to treat your symptoms.
And the cream is available in one strength: 0.01%, of which you can measure doses of 1g, 2g, 3g or 4g into the applicator. Again, the dose you’re prescribed will be the lowest one that helps your symptoms.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
A Randomized, Multicenter, Double-Blind, Study to Evaluate the Safety and Efficacy of Estradiol Vaginal Cream 0.003% in Postmenopausal Women with Vaginal Dryness as the Most Bothersome Symptom. Journal of Women’s Health, [online] 27(3), pp.231–237.
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