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Prevent pregnancy with Tri-Estarylla, an effective combination birth control pill that can help to regulate your periods and PMS symptoms too.

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This page was medically reviewed by Ms Laurenmarie Cormier, Nurse Practitioner on August 02, 2022. Next review due on August 01, 2024.

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What is Tri-Estarylla?

Tri-Estarylla is a combination hormone medication that’s used to prevent pregnancy. It contains two different hormones that work to stop you from getting pregnant: norgestimate and ethinyl estradiol. When used correctly it’s over 99% effective at preventing pregnancy.

It releases varying levels of hormones in the active birth control pills, making it follow your natural cycle more closely. This is known as tri-phasic birth control. This phased dose can be better to control PMS symptoms that are usually associated with your period. Tri-Estarylla comes in packs of 28 pills.

How does Tri-Estarylla work?

The hormones in Tri-Estarylla work in three different ways to prevent pregnancy. First, it stops your body from releasing an egg during ovulation. It also stops your womb lining from thickening so an egg can’t implant itself. Finally, it makes your cervical fluid thicker so that sperm can’t get through.

So it all works together to make pregnancy less likely. Tri-Estarylla can also help to regulate your period and make it lighter. It can even help with PMS symptoms that many women experience during their menstrual cycle.

What doses of Tri-Estarylla are there?

Every package of Tri-Estarylla has 21 active birth control pills and 7 inactive pills. The ‘inactive’ pills don’t have any hormones. Taking a break from the hormones means you can have your period, while still taking the inactive pills helps you remember to take it everyday.

The active birth control pills contain norgestimate and ethinyl estradiol (0.18mg – 0.215mg – 0.25 mg/0.035mg) to phase the delivery of hormones throughout the month. These hormones change through the month on a 7/7/7 basis, which means 7 days at each phase of hormones.

The pills are color-coded to make it simple to identify which dose of hormones they have. You’ll start off taking the white pills for seven days, which have 0.18 mg of norgestimate and 0.035 mg of ethinyl estradiol.

On days 8-15 of each pack of Tri-Estarylla, you’ll take the light blue pills which have the same dose of estrogen and 0.215mg of norgestimate. Then you’ll take the blue pills for seven days, which have 0.25mg of norgestimate. Finally, you take the inactive pills, which are green and don’t contain any hormones.

There’s a low hormone dose version available Tri-Lo-Estarylla which may be better for people who have side effects from birth control with a higher dose of hormones. There’s also a version that gives you the same dose of hormones each month (known as mono-phasic) called Previfem.

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How to take Tri-Estarylla

You should make sure to always follow your clinician’s advice on taking Tri-Estarylla, but it’s pretty simple.

Take one pill a day, at the same time every day. Using an alarm or a medication reminder app on your phone can help you remember. You can also make taking the pill part of your routine, like always taking Tri-Estarylla with breakfast.

Since Tri-Estarylla contains different levels of hormones, it’s important to take the right pill on the right day. Following the arrows on the pack will help you to know which pill you need to take.

How long does it take Tri-Estarylla to work?

There’s a few things that affect how long it takes Tri-Estarylla to protect you against pregnancy. In some cases, you’ll be protected right away.

If you aren’t switching from another method of birth control, and you start taking Tri-Estarylla on the first day of your period, your pill will be effective right away.

If you’ve just had an IUS, vaginal ring or vaginal patch removed on the day you start Try-Estarylla, it should provide protection immediately. It’s the same with birth control pills, mini or combined.

If there’s been a break between switching to Tri-Estarylla, or you haven’t taken birth control pills before and you’re not starting on the first day of your period, you need extra protection. Same with the copper IUD. You’ll need to use a barrier method like condoms for the first seven days.

If you have any questions about starting Tri-Estarylla, just message our clinician. We make it easy to get the advice you need, wherever you are.

What should I do if I make a mistake when taking Tri-Estarylla?

What happens if you forget a pill? Because Tri-Estarylla is a phased pill, it depends on how many you’ve missed, and which type.

If you miss one light blue, blue or white pill (the ones with hormones), just take it as soon as you remember and keep taking Tri-Estarylla as normal. If you miss more than one active pill, you need to use an extra form of birth control like condoms for seven days to prevent pregnancy.

If you’ve forgotten to take a green pill, you’re still protected, as these don’t have hormones. Just skip that day, then take tomorrow’s pill at the right time. If you have any questions, you can message one of our clinicians from your account.
Remember to treat vomiting or diarrhea within three to four hours of taking your pill in the same way you would treat a missed pill.

Taking too much Tri-Estarylla is unlikely to cause any serious problems, but you might have some vaginal bleeding. Always see a clinician for advice if you’re worried about side effects after taking extra Tri-Estarylla.

Medically reviewed by
Ms Laurenmarie Cormier
Nurse Practitioner
on August 02, 2022.
Meet Laurenmarie  
This page was medically reviewed by Ms Laurenmarie Cormier, Nurse Practitioner on August 02, 2022. Next review due on August 01, 2024.

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Tri-Estarylla: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How is Tri-Estarylla different to other birth control pills?

Tri-Estarylla is a phased pill that delivers different amounts of hormones at different times of the month. This matches your cycle more closely than other types of birth control which are monophasic. By being closer to a natural cycle, Tri-Estarylla can lower the risks of side effects and relieve menstrual symptoms.

Is Tri-Estarylla similar to any other birth control pills?

Tri-Previfem, Tri-Sprintec and Ortho Tri-Cyclen are all birth control pills that contain the same levels of the same hormones and are phasic, like Tri-Estarylla. These are all the same type of birth control pills but made by different manufacturers and with slightly different packaging.

Should I use Tri-Estarylla or Tri-Lo-Estarylla?

The main difference between Tri-Estarylla and Tri-Lo-Estarylla is the dose of hormone in each. Both are phased birth control that fits more with fluctuations in the natural menstrual cycle, which can help with PMS symptoms.

Tri-Estarylla birth control pills contain norgestimate and ethinyl estradiol in the following doses: 18mg - 0.215mg - 0.25/0.035mg whereas Tri-Lo-Estarylla contains 18mg - 0.215mg - 0.25mg.

This lower dose of hormones in Tri-Lo-Estarylla means that it’s less likely to cause the hormonal side effects that can be associated with some birth control pills. If you’ve experienced side effects when taking hormonal birth control in the past, then you may benefit from Tri-Lo-Estarylla as an alternative to Tri-Estarylla.

Speak to your doctor about your previous experiences with birth control to help them find the right one for you and your circumstances. There are other options available if you’ve previously tried something you didn’t like or felt side effects from.

How effective is Tri-Estarylla?

The combination of hormones in Tri-Estarylla, norgestimate and ethinyl estradiol, is powerful at preventing pregnancy. It’s been shown to be over 99% effective as birth control. It’s also safe to use, and can have the extra benefit of making your periods lighter and shorter.

Do I need a prescription for Tri-Estarylla?

Yes, Tri-Estarylla is a prescription medication, so a clinician will need to make sure it’s right for you before you can start taking it. Even though the risk of side effects is very low, it’s not suitable for everyone, especially if you have a pre-existing health condition.

Why should I buy Tri-Estarylla online with Treated?

At Treated, we want to help you find the birth control that works for you. Just answer a few questions about your health and we’ll let you know your options.

If Tri-Estarylla is the one, you can order it right to your door. Our clinicians are also at hand if you ever have questions, and we’ll check in with you to make sure you’re happy with your birth control.

With our subscription options, you can pause, change or cancel your birth control deliveries whenever you want. If you want to stock up, space out your deliveries, or get your birth control early so you’re ready for a trip, the options are at your fingertips.
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