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What can you do to prevent gout?

What can you do to prevent gout?

Gout is a form of arthritis that causes swelling, redness, and pain in joints – often in the big toe. Worldwide, it’s thought to affect around 55 million people. Research suggests that men are more likely to develop gout than women, but the risk of gout in women increases after menopause.

Alexandra Cristina Cowell
Medically reviewed by
Alexandra Cristina Cowell, Writer & Clinical Content Reviewer

It can be genetic, or caused by lifestyle factors – but evidence suggests that making changes to your lifestyle can reduce your risk of flare-ups (even if gout is genetic).

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Reviewed on Jun 10, 2026. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Registered with GPhC (No. 2241935) Next review due on Jun 10, 2029.
Alexandra Cristina

Last updated on Jul 08, 2026.

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Lifestyle changes to avoid gout flare-ups

While certain genes can cause gout, some lifestyle choices also increase the risk. These include:

  • Drinking alcohol
  • Smoking
  • Physical activity levels
  • Diet

So let’s take a look at some lifestyle changes you can make to reduce your risk of a gout flare-up.

Limit red meats

Red meat (especially veal and lamb) and organ meats can contain high levels of purines. Your body breaks down purines into uric acid as a waste product, which can lead to gout flare-ups. Most cuts of beef contain moderate amounts of purines, though—so limiting the amount of red meat you eat, and switching to beef from other forms of red meat, can help to reduce your risk of gout flare-ups.

Avoid high-purine fish and shellfish

Some seafood also contains high levels of purines, which your body breaks down into uric acid. High levels of uric acid in your blood can cause gout flares, so it’s best to avoid certain types of high-purine fish and shellfish. Seafood that contains high levels of can purines includes:

  • Tuna
  • Salmon
  • Anchovies
  • Mackerel
  • Herring
  • Trout
  • Sardines
  • Shellfish
  • Roe (fish eggs)

Instead, try switching these out for fish that contain lower levels of purines, like:

  • Cod
  • Haddock
  • Perch
  • Pike

Stop smoking

While smoking can reduce levels of uric acid in the blood, we still don’t know a lot about its impact on gout risk. But we do know that smoking cigarettes has proven to increase the risk of joint inflammation and the development of rheumatoid arthritis. So while smoking may decrease the risk of developing gout, its effects on joint inflammation can lead to flare-ups in people already living with gout.

Exercise regularly

While exercising during a gout flare-up can make inflammation and pain worse, physical activity in between flares can help to protect your joints and reduce your risk of future flare-ups.

Engaging in regular moderate- and low-intensity aerobic exercise can help reduce uric acid levels and inflammation in the body.

But it’s important not to overdo it, because continuous high-intensity physical activity can cause lactic acid to accumulate in your body, which interferes with your excretion of uric acid.

Take vitamin C

Making sure you get enough vitamin C in your daily diet has also shown promising effects on gout risk. Studies on wider populations have found that high vitamin C intake is associated with lower uric acid levels – the main cause of gout flare-ups.

While the reason for this correlation isn’t fully understood, some studies suggest that when humans evolved and lost the ability to produce uricase (which is an enzyme that can metabolize uric acid, turning it into a form that can dissolve in liquid), this caused an evolutionary adaptation that counteracts vitamin C deficiency by increasing uric acid levels in the body. So making sure you get enough vitamin C can help keep uric acid levels lower.

But right now, it’s not clear whether this association is the sole cause of reduced uric acid levels in people with high vitamin C intake. More research still needs to be conducted to explore the link between vitamin C and reduced uric acid levels.

Stay hydrated

Drinking plenty of fluids, and avoiding drinks containing fructose and alcohol can help to improve gout symptoms. Two-thirds of the body’s uric acid is excreted through the kidneys, so drinking plenty of water can help keep your kidneys working properly, and reduce uric acid levels in your system.

Aim to drink around 3 to 4 liters of water a day, and avoid stimulants like alcohol and tobacco which can dehydrate you.

Avoiding alcohol is also important, because it can increase the levels of uric and lactic acid in your body (lactic acid inhibits your body’s excretion of uric acid) which can lead to gout attacks.

It’s not clear how drinking coffee could affect gout. Data suggests that coffee could help lower risk of gout flare-ups, as it’s rich in antioxidants (which can help with uric acid excretion). One study found that the more cups of coffee people drank each day, the lower their risk of gout was. But contradicting research suggests that people with certain genetic variations linked to reduced coffee intake were at a higher risk of gout.

How can genes cause gout?

Genetic gout can be caused by variants of the genes SLC2A9 and ABCG2. Studies show that SLC2A9 was the most statistically significant gene that affects levels of uric acid in the body (also known as serum urate).

Meanwhile, the ABCG2 gene is involved with the process of Glu141Lys amino acid substitution. Research indicates that Glu141Lys changes can cause variations in serum urate levels – with a larger effect on men’s uric acid levels compared to women.

Gout is caused by a buildup of uric acid in the blood, which can form sharp crystals in the joints. These crystals can cause an immune response in your body, leading to inflammation and pain around the joint. So variations in these genes could increase your risk of developing genetic gout.

While there isn’t much you can do to change your risk from a genetic standpoint, following the lifestyle adjustments we’ve discussed here can still reduce your chances of experiencing a gout flare, even if you have a genetic predisposition to the condition.

What to do if your gout flares up

Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen are usually the first-line treatment to relieve pain and swelling caused by gout attacks. They work by blocking enzymes that produce lipid compounds called prostaglandins, which are responsible for your body’s inflammatory and pain responses. This should help reduce inflammation and pain from gout attacks.

Colchichine is a specific medicine to help relieve gout flare-ups. It works by blocking the activation of the NLRP3 inflammasome, which is a pathway that’s responsible for starting the inflammatory response to uric acid crystals in the joints. This can help treat and prevent gout flares.

Other options for gout include allopurinol (known also as Zylorim) and febuxostat – but these tend to be used more to prevent (rather than treat) gout. So you may be prescribed another option alongside these to treat an active flare if you’re experiencing one. Do not stop taking these medications during the gout attack.

If you have any questions about which gout medication is right for you, speak to your clinician or take our online consultation. A healthcare professional will be able to help you find the option that best suits you.

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