Tranexamic acid
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605mg
$169.95 60 tablets
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Reviewed on November 02, 2026. by Dr. Joseph Palumbo Senior Medical Adviser Registered with NPI (No. 1043478878) Next review due on Nov 02, 2029.
Dr. Joseph Palumbo

Last updated on November 02, 2026.

Off-label oral pill for discolored patches of skin.

Tranexamic acid is an antifibrinolytic pill that can be prescribed off-label for melasma. It works by blocking cellular pathways that trigger skin inflammation and pigmentation. The pills can be taken for up to six months at a time.

Price checker

605mg
$169.95 60 tablets
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $169.95
    Save $0.00 each order
Tranexamic acid Tranexamic Acid

What is Tranexamic acid?

Tranexamic acid is a tablet treatment that is used to manage excessive bleeding. It can also be prescribed ‘off-label’ to treat melasma.

Off label prescribing is the practice of using medications outside of their license.[1] Physicians often do this if they think using a medication this way will work effectively.

When it’s used to treat melasma, Tranexamic acid works by reducing inflammation and blocking pathways that contribute to changes in skin pigmentation.

How does Tranexamic acid work?

Tranexamic acid helps treat melasma by blocking chemicals that tell your skin to produce excess pigment.

By changing processes that contribute to dark patches of skin, it can reduce melanin production to help existing dark patches fade, and prevent new discolored patches forming.

The pills can be taken for up to six months, which gives them chances to reduce affected patches of skin gradually.

What doses of Tranexamic acid are there?

Tranexamic acid is available as 650mg pills.

You might be advised to take a quarter, or half of a pill, twice a day for up to six months. Your physician can tell you exactly how much they think you should use, depending on the severity of your symptoms.

Treated trusted source:

  1. FDA (2018). Understanding unapproved use of approved drugs “off label.” U.S. Food and Drug Administration.
Dr. Joseph Palumbo 29191
This page was medically reviewed by Dr. Joseph Palumbo on November 02, 2026. Next review due on November 02, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Tranexamic acid Tranexamic Acid

How to take Tranexamic acid

Tranexamic acid pills can be taken with or without food.

Usually, the pills are swallowed whole. But for treating melasma, you’ll be told to break the pills and take either a quarter, or half, of a pill at a time.

Your physician will tell you the best way to do this, and how much you need to take each day.

How long does Tranexamic acid take to work?

The effects of Tranexamic acid might differ person-to-person, so there’s no guarantee how long it will take to work for you.

You might notice changes to your skin’s appearance after you’ve been taking the pills for only a short time, such as a couple of weeks. But it’s important you maintain your dosage routine for as long as you’ve been advised to.

Because Tranexamic acid can be taken for up to six months, it’s a long-term treatment for melasma that might work gradually, rather than quickly.

What should I do if I make a mistake when taking Tranexamic acid?

Take Tranexamic acid exactly how you’ve been advised to. Because the pills are prescribed off-label, you’ll be given specific instructions about how much to take each day, and when to take them. If you forget to take a dose, you can take your quarter

Taking more than the recommended amount won’t work more effectively to improve your melasma symptoms, and could cause unwanted side effects.

Dr. Joseph Palumbo 29191
This page was medically reviewed by Dr. Joseph Palumbo on November 02, 2026. Next review due on November 02, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Tranexamic acid Tranexamic Acid

Tranexamic acid isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let your physician know, and they can talk with you about it.

Tranexamic acid Tranexamic Acid

Tranexamic acid: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How effective is Tranexamic acid for treating melasma?

Answer:
Studies have shown tranexamic acid to be effective at treating melasma when taken in low doses, and for short periods of time, such as 8-12 weeks.[1]

It might be prescribed if other first-line treatment options like topical hydroquinone haven’t worked.

Will Tranexamic acid improve my melasma?

Answer:
There’s no guarantee that Tranexamic acid will improve your melasma, but it has been shown to be effective.[1] Melasma is sometimes managed by using a combination of treatments, such as tretinoin, hydroquinone and a topical corticosteroid.

Your physician will ask you about treatments you’ve used in the past, or are currently using, to manage your symptoms. They might recommend using a topical medication alongside the pills if they think doing so will work effectively.

How long can I take Tranexamic acid for?

Answer:
Tranexamic acid can be taken daily for up to six months. The length of time you’ll need to use this treatment will depend on how your body responds to it.

Melasma can sometimes be temporary, such as when symptoms develop during pregnancy, which means you might not need to use Tranexamic acid long-term. But if you feel like the pills are helping to improve your skin, you can use them for the full six months.

A small study of people taking Tranexamic acid to treat melasma beyond six months showed that it was effective and well tolerated,[2] but using it for this amount of time would need to be approved and supervised by your physician.

Can I drink alcohol with Tranexamic acid?

Answer:
You’ll need to speak to your clinician about drinking alcohol while taking Tranexamic acid.

While the patient leaflet that comes with your tablets might not mention to avoid alcohol specifically, for some people alcohol might contribute to or make melasma symptoms worse. Alcohol can cause cellular inflammation in your skin, which could affect the appearance of the melasma-affected patches you’re trying to treat.

Can I get Tranexamic acid through private health insurance?

Answer:
You’ll need to check with your health insurance provider to see what is covered by your plan. Off-label prescribing can sometimes affect coverage, and certain providers might deny a specific medication if it’s being used outside of its license.

So by speaking to them directly, you’ll know exactly where you stand before starting treatment. If Tranexamic acid isn’t included in your plan and you still want to use it, you’ll have to pay for it out of pocket and order it from an online healthcare service.

Treated trusted source:

  1. Bala, H.R., et al (2018). Oral tranexamic acid for the treatment of melasma: A review. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 44(6), pp.814–825.
  2. Lam, K., Mansour, D. and Sutton, A. (2024). Oral tranexamic acid treatment beyond 6 months for melasma patients – A retrospective case series. JAAD international, 15, pp.195–196.

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