Pepcid
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Reviewed on Mar 02, 2025. by Dr. Joseph Palumbo Senior Medical Adviser Registered with NPI (No. 1043478878) Next review due on March 03, 2028.
Dr. Joseph Palumbo

Last updated on Mar 02, 2025.

Product info

  • Pepcid is a H2 blocker that reduces stomach acid to relieve heartburn and acid reflux.

  • Starts working within an hour to provide symptom relief.
  • Available in 10 & 20mg doses.

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$129.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $129.95
    Save $0.00 each order
Pepcid Famotidine

What is Pepcid?

Pepcid is a medication commonly used to treat acid reflux and heartburn. It is the brand name for its active ingredient, famotidine. Famotidine belongs to a class of drugs known as H2 blockers. These medications work by reducing the amount of acid your stomach produces, helping to relieve discomfort caused by excess acid, such as heartburn, indigestion, and gastroesophageal reflux disease (GERD).

How does Pepcid work?

Pepcid (famotidine) works by binding to and blocking histamine H2 receptors in the stomach lining. Histamine is a chemical that stimulates acid production. By stopping histamine from binding to these receptors, famotidine reduces the amount of acid your stomach produces, which then helps relieve symptoms like heartburn and acid reflux. This also helps protect the esophagus and stomach lining from damage caused by excess acid.

What doses of Pepcid are there?

Pepcid typically comes in doses of 10 or 20mg. There’s Pepcid AC, which is a whole tablet you take with water, and Pepcid Complete, which is a chewable tablet.

treated.com This page was written by The Treated Content Team.
Dr. Joseph Palumbo 29191
This page was medically reviewed by Dr. Joseph Palumbo on March 03, 2025. Next review due on March 03, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Pepcid Famotidine

How to take Pepcid

For tablets:

Swallow the tablet whole with water. It can be taken with or without food.

For chewable tablets: 

Chew thoroughly before swallowing.

Take once or twice a day as directed. For heartburn prevention, take a tablet around 30 minutes before eating.

How long does it take Pepcid to work?

Pepcid generally starts working within 30 to 60 minutes after taking it, and it should provide symptom relief for up to 12 hours.[1]

What should I do if I make a mistake when taking Pepcid?

If you miss a dose, take it as soon as you remember. If too much time has passed and it’s nearly time for your next dose, just skip it and take your next dose as normal. Don’t double up on tablets to make up for a missed dose.

Treated trusted source:

  1. Nguyen, K., Dersnah, G.D. and Ahlawat, R. (2022). Famotidine. [online] PubMed
treated.com This page was written by The Treated Content Team.
Dr. Joseph Palumbo 29191
This page was medically reviewed by Dr. Joseph Palumbo on March 03, 2025. Next review due on March 03, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Pepcid Famotidine

Pepcid isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let a clinician know, and they can talk with you about it.

Pepcid Famotidine

Pepcid: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How is Pepcid different from other treatments for GERD?

Answer:
Pepcid is an H2 blocker, meaning it stops histamine from binding to its receptors in your stomach. This then reduces and stops excess acid production. Other treatments for GERD also work to stop excess acid production, but they do it in a slightly different way. For example, proton pump inhibitors (PPIs) like omeprazole and lansoprazole work by blocking the enzyme in your stomach lining that produces acid.

There are also antacids, which work by neutralizing stomach acid that’s already there, rather than stopping it from being produced. Antacids are normally better for fast-acting relief, whereas treatments like Pepcid are better for ongoing prevention and management of GERD. PPIs are often prescribed for more severe cases of GERD.

Can I drink alcohol while taking Pepcid?

Answer:
While Pepcid does help to reduce acid production, drinking alcohol can still irritate your stomach lining and worsen your acid reflux symptoms. It’s best to limit your alcohol intake while using Pepcid.

Does Pepcid cause side effects?

Answer:
Like any medicine, Pepcid can sometimes cause side effects, but not everyone will experience them. Common side effects include headache, dizziness, constipation, and diarrhea.

There are some more serious side effects that are rare but important to be aware of. If you experience any signs of allergic reaction, irregular heartbeat, or confusion, seek medical attention immediately.

How effective is Pepcid?

Answer:
Pepcid works effectively to reduce heartburn and GERD symptoms. In a study on famotidine - the active ingredient in Pepcid - results showed that 70-80% of patients had symptom relief within two weeks.[1] It also showed that the typical 20mg dose can reduce gastric acid significantly within an hour, and keeps those effects up for the 10-12 hours.

Do I need a prescription for Pepcid?

Answer:
No, you don't need a prescription for Pepcid. It is available over the counter for treating GERD.

Treated trusted source:

  1. Nguyen, K., Dersnah, G.D. and Ahlawat, R. (2022). Famotidine. [online] PubMed

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