What is Acitretin?
Acitretin is an oral retinoid used to treat severe skin conditions like lichen planus, a chronic inflammatory condition. Symptoms of lichen planus typically include raised purple bumps in areas like your back, wrists, genitals, and ankles.
Most cases aren’t serious and usually resolve on their own within two years. Acitretin is often considered a last resort if other treatments aren’t working.
Acitretin is used off-label for lichen planus. This is a common practice, and simply means that the drug hasn’t been specifically approved by the FDA for this use. But your doctor will only prescribe it in this way if they think it’s going to be safe and effective for you.
How does Acitretin work?
Acitretin has anti-inflammatory effects. It stops your body making pro-inflammatory molecules that cause swelling, which helps to reduce the raised purple bumps associated with lichen planus.[1]
Additionally, it increases cell turnover, allowing old skin to shed more quickly and new skin to form, which can help clear your bumps and fade marks.[1]
Will I get side effects with Acitretin?’
Yes, you might experience side effects while taking Acitretin, although not everyone will. Possible side effects include:
- Dry mouth, skin, or lips
- Irritated nose
- Headache
- Fragile skin
Acitretin can reduce oil production, leading to unwanted dryness. It’s recommended to use a thick moisturizer and regularly apply lip balm to help combat dryness while taking it. For the full list of side effects, refer to the package leaflet that comes with your medicine.
Does Acitretin interact with any medicines?
Acitretin can interact with several medications, including antibiotics and antifungals. It’s important to inform your doctor about any medications you’re taking so they can check whether Acitretin is safe and suitable for you.
What doses of Acitretin are there?
Acitretin comes in a single dose of 25 mg. The usual dose is one tablet taken once daily for up to four weeks.
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