Naratriptan is a generic tablet treatment. It’s part of a group of medicines called ‘triptans’ which specifically work against migraine headaches (with or without aura). Triptans, including Naratriptan, are symptom relievers rather than preventers. This means that Naratriptan won’t work to prevent or lower the regularity of your migraines. You take them when you first start to experience symptoms, and they work to alleviate your migraine symptoms so that you can continue with your day.
Migraine headaches are a specific type of headache. Sometimes people get indications that they’re about to get a migraine (called aura), but sometimes they can appear quite suddenly. Typical symptoms include a painful ‘throb’ on one side of the head, accompanied by increased sensitivity to light and sound. It’s not fully known what causes them, but it’s thought that they’re often triggered by specific things, such as tiredness, stress, or certain foods or drinks.
How does Naratriptan work?
Once a migraine has been triggered, it sets off temporary changes to your brain – including a widening of your brain’s blood vessels. This allows more pain and nausea signals to be sent to your brain, which gives you your migraine symptoms.
Naratriptan is a serotonin agonist. This means that it binds to the serotonin receptors in your brain, causing the widened blood vessels to re-constrict, which reduces the transmission of pain signals. This, in turn, can help both your symptoms of pain and nausea.
What doses of Naratriptan are there?
Naratriptan is available in two doses: 1mg and 2.5mg. The starting dose is 2.5mg, which can be followed by another 2.5mg tablet after four hours (and only one for the same migraine). The maximum dose is 5mg within 24 hours.
If Naratriptan isn’t helping you with your symptoms as you’d hoped, you should speak to our doctor. It might be the case that you need to try an alternative medicine.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr. Joseph Palumbo on November 28, 2024. Next review due on November 28, 2027.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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How to take Naratriptan
You should always take Naratriptan exactly as prescribed by our physician. To take Naratriptan, simply swallow one tablet whole, with water. If your symptoms aren’t improving, don’t take another tablet.
You shouldn’t exceed more than 2.5mg in four hours, or more than two (5mg total) in 24 hours.
How long does it take Naratriptan to work?
Naratriptan is a rapidly absorbed treatment, and you should start to feel relief within two hours of taking it. If you don’t feel symptom relief for the same migraine after four hours, don’t take another one – contact our doctor for advice.
Naratriptan takes a little longer to work than many other triptans, but this is countered by the fact that it stays in your system for longer. Where other triptans, like sumatriptan, only stay in your system for around three hours, Naratriptan works to alleviate your symptoms for six – making you less likely to need to take another tablet if your migraine recurs.
What should I do if I make a mistake when taking Naratriptan?
If you take more Naratriptan than you should, seek medical advice immediately.
As Naratriptan isn’t a schedule-based treatment, you shouldn’t need to worry about missing a dose.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr. Joseph Palumbo on November 28, 2024. Next review due on November 28, 2027.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Naratriptan isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.
Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.
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Naratriptan: FAQ
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
How is Naratriptan different from other migraine treatments?
Answer:
Migraine meds typically come in the form of either triptans, painkillers, or antiemetics (anti-sickness medications). There are also drugs that contain a combination of painkiller and antiemetic. You might find that different types of medicines work better for you depending on your health needs. You can also get treatments that come in the form of powder sachets or nasal sprays if you prefer not to take tablets.
Within the category of triptans, as well, there are differences between treatments. Some triptans work more quickly to ease your symptoms, whereas other treatments stay active in your system for a long time, which might suit you better if you get migraines that frequently recur. If you’re not sure which migraine treatment might be best for you, talk to us about your health. Our expert clinicians should be able to point you in the right direction based on your health needs.
Is Naratriptan similar to any other treatments?
Answer:
There’s a branded version of Naratriptan called Amerge. Both of these treatments contain the same active ingredient in the same dose - they’re just produced in different labs and branded differently. As a result, they’ll work in largely the same way to treat your symptoms, they might just differ a bit in terms of cost and appearance. As Naratriptan is the generic equivalent, it’s usually a little cheaper.
How effective is Naratriptan?
Answer:
Naratriptan has been proven to be an effective migraine treatment, even working to provide symptom relief to people who didn’t respond to sumatriptan, another ‘triptan’ treatment for migraines.[1] It also showed considerably better headache relief than placebo, both two and four hours after dosing - 69% vs. 31% and 80% vs. 39%, respectively.[2]
Do I need a prescription for Naratriptan?
Answer:
Yes, you need a prescription for Naratriptan. This is because it isn’t suitable for everyone, and shouldn’t be used for regular tension headaches. As a result, a doctor will need to make sure that it’s both safe and relevant for you before they can prescribe it.
Treated trusted source:
Stark, S., et al. (2000).Naratriptan Efficacy in Migraineurs Who Respond Poorly to Oral Sumatriptan. Headache: The Journal of Head and Face Pain, 40(7), pp.513–520.
Havanka, H., et al. (2000).Efficacy of naratriptan tablets in the acute treatment of migraine: A dose-ranging study. Clinical Therapeutics, 22(8), pp.970–980.
Last updated on Nov 27, 2024.
How we reviewed this page:
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Nov 27, 2024
Published by: The Treated Content Team.Medically reviewed by: Dr. Joseph Palumbo, Senior Medical Adviser
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Dr. Joseph Palumbo
Senior Medical Adviser
Joseph joined Treated in 2023, and is one of the lead doctors providing prescribing services for the platform.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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