Metoclopramide is a drug used to alleviate nausea, and it works by interfering with the signals in the body which are communicated from the CTZ (chemoreceptor trigger zone) to initiate the spasming reflex which results in sickness. The drug is a generic version of Maxolon, which also contains metoclopramide, and is manufactured by Actavis. In most cases the dose will be three tablets a day, and a recommended course will not last for more than five days.
- Relieves and prevents nausea
- Three a day tablet
- Can be taken alongside painkillers
Nausea is a condition characterised by the feeling of sickness, or need to be sick. A lot of the time, it can result in actual sickness, or vomiting. There are a number of reasons why someone may experience the sensation. It can sometimes be an expected side effect of treatment for a serious illness, such as chemotherapy or radiotherapy. At other times, it may one of the symptoms of an impending migraine, also known as aura. Sometimes it can come about as a result of disturbance in the gut.
Simply put, the feeling occurs when an irritated part of the body sends messages to the CTZ. This irritant might be certain nerves in the stomach in cases where the gut is struggling to digest food. The CTZ may also respond to the presence of medicinal chemicals in the blood, such as those used in chemotherapy, or the inflammatory substances released by the brain during the early stages of a migraine.
When active, the CTZ then sends signals via a chemical neurotransmitter, called dopamine, to the vomiting centre. It is the vomiting centre from which signals that cause feelings of sickness and spasming in the gut originate. The active constituent of metoclopramide, which is a drug of the same name, works in the chemoreceptor trigger zone to limit the activity of dopamine. This stops the chemical sequence which results in nausea.
This drug is an example of a generic medicine. This means that it is a licensed but non-branded version of a name product, on which the sole production patent has expired. It is important to know which products are available for licensed reproduction when buying treatment online, as some less reputable sites may claim to sell generics which do not yet legally exist.
Metoclopramide is currently not provided through our UK pharmacy service. Persons seeking a prescription for this item are advised to see their regular GP.
Keep to the directions issued by your prescriber when using this treatment, and read the patient information leaflet provided beforehand. This will help you to limit the potential side effects and get the best possible results from your treatment.
- Use as specified by your doctor.
- The usual dose will be one tablet taken up to three times daily.
- A course will last a maximum of five days.
- Leave at least six hours between doses.
- Never exceed the prescribed amount, even if you are sick and reject the tablet.
- If you miss a dose, do not take a double dose to compensate. Simply take your next dose at the scheduled time.
The above is only a summary of the directions you will need to adhere to when using this item. Consult the leaflet before use.
Like most other prescription treatments, this item may cause side effects. It is vital to be aware of these prior to use, so that you can respond accordingly in the event that they occur. Seek immediate medical attention if you notice any signs of an allergic reaction, neuroleptic malignant syndrome, uncontrollable movements, or any other responses which cause you concern. More information on what these reactions look like can be found in the safety leaflet provided.
Very common (1 in 10 people or more):
Common (1 in 10 people or less):
Depression, uncontrollable movements including tics, shaking or muscle contracture, rigidity, tremor, feelings of being restless, drop in blood pressure, diarrhoea or weakness.
Uncommon (1 in 100 people or less):
Increase in prolactin, hallucination, irregular periods, or slowed heartbeat.
Rare (1 in 1,000 people or less):
Confusion, or convulsions in epileptic patients.
The above is not a complete list of the side effects associated with this medication. Further details can be found in the product leaflet.
Taking it with other medicines
Inform your prescriber during consultation if you are using any other treatments. The following may interact with Metoclopramide or hinder its function: levodopa or other drugs used to treat Parkinson’s disease; anticholinergics; morphine derivatives; sedatives; any treatments for mental health problems; digoxin; ciclosporin; mivacurium and suxamethonium; or fluoxetine and paroxetine.
Conditions to look out for
The use of this treatment may not be safe for those with certain conditions. Do not use it if you have: bleeding, a suspected obstruction or a tear in your stomach or gut; pheochromocytoma; Parkinson’s disease; a history of involuntary muscle spasms; epilepsy; or if you have ever had irregular blood pigment levels.
It may also not be suitable for those who have or have ever had: irregular heartbeat or heart problems of any type; lactose intolerance; problems with blood salt levels; any neurological problems; or liver or kidney problems.
Can I still drink alcohol?
It is important to refrain from consuming alcohol when using this treatment, as drinking alcohol may increase the risk of sedative effects.
Will I still be able to drive?
The presence of certain side effects, such as reduced control over bodily movements, may make it unsafe to drive. If you experience anything which could cause you difficulty when driving, refrain from doing so and speak to your doctor immediately.
Can I use this medicine while pregnant?
It may not be suitable for those who are pregnant or breastfeeding. Let your prescriber know if you are pregnant, breastfeeding or trying to become pregnant, as they may choose to suggest an alternative form of treatment.
How do I store it?
Keep it in a safe place, out of the reach of children, below 25°C.
Am I allergic to anything in the medicine?
This product contains: metoclopramide hydrochloride, colloidal silica, lactose, magnesium stearate, maize starch, and microcrystalline cellulose (E460).
Do not use it if you are allergic to any of these ingredients.
Is it available over-the-counter?
In order to buy metoclopramide from any UK pharmacist, you will need first to consult with a doctor. This is necessary to make sure that the product is suitable for you prior to use.
Is it right for me?
At present, Metoclopramide is not available to buy from our UK pharmacy. If you are seeking a prescription for this particular medicine, we would advise you to make an appointment with your doctor in person.
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