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Reviewed on May 23, 2025. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Next review due on May 23, 2028.
Dr Alexandra Cristina Cowell

Last updated on May 23, 2025.

The PrEP tablet that treats and prevents HIV.

Truvada is a tablet treatment for HIV that can also reduce your chances of developing the virus. It’s usually taken daily, depending on your medical history and lifestyle.

Price checker

200mg/300mg
$2,324.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $2,324.95
    Save $0.00 each order
Truvada Tenofovir disoproxil fumarate/Emtricitabine

What is Truvada?

Truvada is a PrEP treatment for people with HIV, a viral infection that weakens your immune system.

It’s taken daily to treat HIV and reduce the risk of contracting it.

How does Truvada work?

Truvada contains two active ingredients: tenofovir and emtricitabine, which are antivirals.

They work together to stop the virus from replicating and spreading.[1][2] It’s not a cure for HIV, as it doesn’t completely eliminate the virus, but it can significantly reduce the viral load in your body.

Will I get side effects using Truvada?

There’s a risk of getting side effects when using Truvada, such as:

  • Dizziness
  • Headache
  • Rash
  • Feeling weak

The side effects are typically mild and should subside as your body adjusts to the medicine.

Is there a generic version of Truvada?

Yes, there’s a generic version of Truvada simply known by the active ingredients it contains.

Generic treatments are as effective as the branded ones, with the main difference being the price – typically, the generic version is cheaper.

What doses of Truvada are there?

Truvada is available in four doses containing either:

  • 200 mg of emtricitabine and 245 mg of tenofovir disoproxil,
  • 100mg of emtricitabine and 150 mg of tenofovir disoproxil,
  • 133mg of emtricitabine and 200 mg of tenofovir disoproxil, or:
  • 167mg of emtricitabine and 250 mg of tenofovir disoproxil.

Treated trusted source:

  1. Drug Bank (n.d.). Tenofovir disoproxil. go.drugbank.com.
  2. Drug Bank (n.d.). Emtricitabine. go.drugbank.com.
Dr Alexandra Cristina Cowell 23938
This page was medically reviewed by Dr Alexandra Cristina Cowell on May 23, 2025. Next review due on May 23, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Truvada Tenofovir disoproxil fumarate/Emtricitabine

How to take Truvada

How you take Truvada depends on whether you’re treating HIV or reducing your risk of getting it.

Treating HIV

  • Take one tablet every day, preferably with food.
  • Take it at the same time every day.

Reducing the risk of getting HIV (On-demand)

Taking Truvada on demand is an off-label use. This means it’s not licensed to use it this way, but your clinician might recommend it if they think it’s safe and effective for you.

Follow the 2-1-1 rule

  • Take 2 tablets 2-24 hours before you have sex.
  • Take 1 tablet within 24 hours after you have sex.
  • Take 1 tablet 24 hours after the last pill.

If you’re having sex multiple times, take one pill every 24 hours until you’ve not had sex for two days.

What to do if you miss a dose of Truvada

If it’s been less than 12 hours, take the tablet as soon as possible and continue with your normal dosing schedule.

If it’s been more than 12 hours, skip the missed dose and continue with your normal dosing schedule.

Dr Alexandra Cristina Cowell 23938
This page was medically reviewed by Dr Alexandra Cristina Cowell on May 23, 2025. Next review due on May 23, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Truvada Tenofovir disoproxil fumarate/Emtricitabine

Truvada isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our doctor know, and they can talk with you about it.

Truvada Tenofovir disoproxil fumarate/Emtricitabine

Truvada: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How does Truvada compare with Descovy?

Answer:
Descovy is a branded medication for HIV. It contains emtricitabine and tenofovir alafenamide, and works by preventing viral replication. This is similar to Truvada, with the main difference being the chemical structure of the tenofovir version.

Aside from this, both drugs are essentially the same, but there may be a difference in packaging, price and inactive ingredients.

Can I get Truvada without a prescription?

Answer:
No, you’ll need a prescription from a registered clinician to get Truvada. This is so they can check it’s safe, effective and suitable for you.

How effective is Truvada?

Answer:
Studies have shown that taking Truvada seven days a week offers up to 99% protection. This is reduced to 96% if taken four days a week and 76% for two days a week.

Although Truvada offers protection against HIV when not taken daily, consistent daily use increases its effectiveness significantly.[1]

Can I stop taking Truvada?

Answer:
Don’t stop taking Truvada unless your clinician advises you to do so. Stopping treatment can reduce your HIV protection.

If your HIV status changes, your clinician will let you know and will discuss how to continue your treatment.

How long does it take for Truvada to work?

Answer:
If you're using Truvada daily, it will take seven days to build up protection.

If you're taking it on demand, following the 2-1-1 rule should offer sufficient protection. But if you’re having sex multiple times, you should continue taking Truvada until you’ve had two sex-free days. This is an off-label use and your clinician will only recommend taking it this way if they think it’s safe and suitable for you.

Can I get Truvada through private health insurance?

Answer:
Private healthcare plans may cover Truvada, but it depends on the plan you're on. It’s best to check with your insurer to see if Truvada is covered.

If Truvada isn’t covered, your insurance may cover a similar or generic version. Otherwise, if it isn’t covered by your insurance but you’d still prefer to buy it anyway, you’ll be able to do this directly from an online pharmacy.

Treated trusted source:

  1. Sundareshan V, Swinkels HM, Nguyen AD, et al. Preexposure Prophylaxis for HIV Prevention. [Updated 2024 Jan 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.

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