Hyperhidrosis is a medical condition where you sweat excessively. There are many treatments available to reduce sweating, each differently suited to different parts of your body. Some areas of skin are thicker and have more sweat glands than others, so your treatment can be tailored accordingly.

The skin on your armpits is much thinner than it is on other parts of your body, making it more sensitive. Using harsh products can cause it to get irritated. As a result, roll-ons are a convenient option for underarm hyperhidrosis.
Drysol, Xerac AC, and Certain Dri are prescription and clinical-strength roll-on treatments for excessive sweating. These options contain aluminum chloride hexahydrate, which works by forming a plug in your sweat ducts to block the release of sweat – basically like a sink plug but for your underarm. It’s usually applied for two consecutive nights, followed by a two-day break. If you have sensitive skin, you can take a longer break in between, but this might make it less effective.
Side effects like mild skin irritation, redness, and itching are common with Drysol, Xerac AC, and Certain Dri. Using hydrocortisone, a mild steroid, can reduce swelling, itching, and redness. Simply apply it the morning after applying the treatment.
Another thing you can use is absorbent pads. These pads are attached to your clothes to help absorb excess sweat. While it’s not a treatment per se, it can still be a useful option.
Hands and feet have thicker skin, which allows for the use of stronger treatments. You can use Drysol, Xerac AC, or Certain Dri, applying them in the same manner as you would on your underarms. But for better absorption, wear socks or gloves after application.
Another effective treatment option uses an iontophoresis machine, which has shown promising results in studies. You place your hands and feet in trays filled with water, through which a weak electrical current passes to the skin. Although the exact way it reduces sweating isn’t fully understood, it’s believed to:
While the iontophoresis machine can be costly, think of it as an expensive upfront investment for a lifetime treatment for hyperhidrosis
If for any reason you prefer not to use medication or treatment, a quick and easy method is to wear moisture-wicking gloves and socks. As the name suggests, they effectively absorb excess sweat, helping to keep your hands and feet dry.
Your face is one of the most sensitive areas of your body, so it’s best not to use harsh treatments on it like Drysol. There are iontophoresis machines available for your face, but they are more pricey than the ones for hands and feet.
As a result, oral treatments (like Oxybutynin or Glycopyrrolate) may be the best option for managing facial hyperhidrosis. Both of these medications are used off-label for hyperhidrosis, meaning they aren’t officially approved for this condition, but your doctor may recommend them if they believe they’ll be safe and effective for you.
These medications work similarly, by blocking the nerve signals that stimulate the sweat glands, and need to be taken daily. Additionally, both medications may cause side effects, so it’s important that you read about them so you know what to expect. The choice between the two will depend on your preferences and what works best for you.
Botox (botulinum toxin A) is another option. One study found Botox to be a safe and effective way to treat excessive sweating on the face. Participants experienced a noticeable drop in sweating just four weeks after receiving treatment. For 9 out of the 10 people involved, the benefits continued for at least five months. Also, all patients who took part in the study reported that the treatment worked extremely well and were very satisfied with the results.
Your back and chest are larger areas of skin, which can make treatment more challenging. While roll-on antiperspirants can be used, you’ll need to use a large amount of them to cover the entire area. As a result, it’s often better to use oral medications such as Oxybutynin or Glycopyrrolate.
Some other things you can do to reduce or mask sweating include:
| Area | Best Treatment |
|---|---|
| Underarm | Roll-ons |
| Hands/Feet | Roll-ons Iontophoresis |
| Face | Oral medication; Iontophoresis; Botox injections |
| Back/Chest | Oral medication |
Treatment of Palmar Hyperhidrosis with Tap Water Iontophoresis: A Randomized, Sham-Controlled, Single-Blind, and Parallel-Designed Clinical Trial. Annals of Dermatology, 29(6), 728.
Iontophoresis - International Hyperhidrosis Society | Official Site. Www.sweathelp.org.
Effective treatment of frontal hyperhidrosis with botulinum toxin A. British Journal of Dermatology, 143(4), pp.824–827.
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Last updated on Jul 17, 2026.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Jul 17, 2026
Published by: The Treated Content Team. Medically reviewed by: Dr Alexandra Cristina Cowell, Writer & Clinical Content ReviewerHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Writer & Clinical Content Reviewer
Cristina writes content for Treated, and reviews content produced by our other writers to make sure it’s clinically accurate.
MeetHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.