Ciprofloxacin/Dexamethasone
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Reviewed on February 11, 2026. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Registered with GPhC (No. 2241935) Next review due on Feb 09, 2029.
Dr Alexandra Cristina Cowell

Last updated on February 11, 2026.

Daily ear drops for bacterial ear infections.

Ciprofloxacin/Dexamethasone is a combination treatment containing an antibiotic and a steroid. It works by killing the bacteria and reducing swelling and pain.

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0.3%/0.1%
$184.95 1 x 7.5ml bottle
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $184.95
    Save $0.00 each order
Ciprofloxacin/Dexamethasone Ciprofloxacin/Dexamethasone

What is Ciprofloxacin/Dexamethasone?

Ciprofloxacin/Dexamethasone is a combination treatment that contains an antibiotic and a steroid. This makes it suitable for treating otitis externa, commonly known as swimmer’s ear. Typical symptoms include ear pain, itching, swelling, redness, and hearing loss. It usually occurs when water gets trapped in the ears, creating an environment for bacteria to thrive.

Ciprofloxacin/Dexamethasone can help treat otitis externa by killing the bacteria and reducing inflammation.

How does Ciprofloxacin/Dexamethasone work?

Ciprofloxacin is an antibiotic that works by inhibiting DNA replication in bacteria. This prevents the bacteria from growing and replicating, which eventually leads to their expiry.[1]

Dexamethasone is a corticosteroid that works by stopping inflammation and promoting anti-inflammatory effects. This helps reduce swelling, inflammation, pain, and redness.[2]

Together, these ingredients help to treat and relieve the symptoms of otitis externa.

Will I get side effects using Ciprofloxacin/Dexamethasone?

There’s a chance of experiencing side effects while using Ciprofloxacin/Dexamethasone, although not everyone will get them. Common side effects include mild ear pain, which should subside after a few days.

Other possible side effects might include ear discomfort, ear congestion, hearing issues, and scaling in the ear. For a full list of possible side effects, check the package leaflet that comes with your medicine.

What doses of Ciprofloxacin/Dexamethasone are there?

Ciprofloxacin/Dexamethasone is available in one dose containing 0.3% Ciprofloxacin and 0.1% Dexamethasone. You typically apply one to two drops in the affected ear, daily until the infection clears.

Treated trusted source:

  1. Thai, T., et al. (2023). Ciprofloxacin. [online] National Library of Medicine.
  2. Johnson, D.B., et al. (2023). Dexamethasone. [online] PubMed.
Dr Alexandra Cristina Cowell 23938
This page was medically reviewed by Dr Alexandra Cristina Cowell on February 09, 2026. Next review due on February 09, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Ciprofloxacin/Dexamethasone Ciprofloxacin/Dexamethasone

How to use Ciprofloxacin/Dexamethasone

To use Ciprofloxacin/Dexamethasone:

  1. Wash your hands thoroughly.
  2. Warm the bottle in your hand for a few minutes by rubbing it.
  3. Lie down on your side with your ear facing up.
  4. Squeeze the bottle to instill two drops into your ear.
  5. Pull the earlobe outward and upward to allow the medicine to flow into the ear canal.
  6. Remain in this position for 5 minutes.
  7. Repeat the process for the other ear (if affected).

It can be helpful for someone else to apply the drops to your ear to make the application process easier.

Dr Alexandra Cristina Cowell 23938
This page was medically reviewed by Dr Alexandra Cristina Cowell on February 09, 2026. Next review due on February 09, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Ciprofloxacin/Dexamethasone Ciprofloxacin/Dexamethasone

Ciprofloxacin/Dexamethasone isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our doctor know, and they can talk with you about it.

Ciprofloxacin/Dexamethasone Ciprofloxacin/Dexamethasone

Ciprofloxacin/Dexamethasone: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Can I get Ciprofloxacin/Dexamethasone through private health insurance?

Answer:
This depends on your private insurance plan. Certain insurers only cover specific brands, but it’s always best to ask your provider whether they cover your preferred treatment.

If it isn’t covered, you can always get Ciprofloxacin/Dexamethasone from an online service, but this will be at your own expense.

Is Ciprofloxacin/Dexamethasone available over the counter?

Answer:
No, you’ll need a prescription for Ciprofloxacin/Dexamethasone from a doctor so they can check if the treatment is suitable and safe for you.

How well does Ciprofloxacin/Dexamethasone work for Otitis externa?

Answer:
Research shows that Ciprofloxacin/Dexamethasone is an effective treatment for otitis externa. In one study, the clinical cure rate (symptom resolution) was 90% by day 18, and the microbiological cure rate (eradication of bacteria) was nearly 95%. These results show it can be an effective treatment at eliminating bacteria and treating the infection. Additionally, the treatment was well tolerated by patients.2

Is Ciprofloxacin/Dexamethasone safe to use while pregnant or breastfeeding?

Answer:
Ciprofloxacin/Dexamethasone is only absorbed into your body in very small amounts after administration in the ear. Still, it’s best to avoid using Ciprofloxacin/Dexamethasone while pregnant or breastfeeding without talking to a doctor first, to prevent the risk of harm to your baby. If you are pregnant or breastfeeding, a clinician may only recommend this medication if they’re confident that the benefits outweigh the potential risks.

How long does Ciprofloxacin/Dexamethasone take to work?

Answer:
Ciprofloxacin/Dexamethasone works quickly, reaching peak concentrations within one hour.1 But it can take up to a week or two for the infection to clear. During this time, make sure to continue using the medicine daily to prevent your symptoms from worsening and reinfection.

Treated trusted source:

  1. Medicines.org.uk. (2025). Ciprofloxacin/dexamethasone 3mg/ml + 1mg/ml ear drops, suspension – Summary of Product Characteristics (SmPC) – (emc) | 101381.
  2. Roland, P.S., et al. (2004). Efficacy and safety of topical ciprofloxacin/dexamethasone versus neomycin/polymyxin B/ hydrocortisone for otitis externa. Current Medical Research and Opinion, 20(8), pp.1175–1183.

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