Clotrimazole

What is Clotrimazole?

Clotrimazole is an antifungal cream that treats fungal skin infections, such as paronychia. Paronychia can be caused by either bacterial or fungal infection and is characterized by redness and inflammation around the nail bed.

Clotrimazole cream is used off-label for the treatment of paronychia, which simply means that its use for this condition is not explicitly specified on the label. But it’s effective for fungal skin infections like paronychia, so your clinician will only recommend it because there’s good evidence that it works.

Fungal paronychia is often referred to as chronic paronychia, because it develops slowly and may take several months to clear completely. Clotrimazole is typically applied twice a day until your doctor advises you to stop.

How does Clotrimazole work?

Clotrimazole works by stopping the production of ergosterol, a component of the fungal cell wall. Without ergosterol, the fungi cannot grow or survive, making it easier for your immune system to clear the infection.^[1]

Will I get side effects using Clotrimazole?

Most people don’t get side effects when using Clotrimazole cream. You might experience some mild irritation or a burning sensation, but this should only last a short while. If irritation, discomfort, or pain persists, consult your doctor.

What concentrations of Clotrimazole are there?

Clotrimazole comes as a 1% cream. The typical dose is to apply it twice daily. Your doctor will inform you how long you need to continue the treatment.

How to use Clotrimazole

Apply a small amount of Clotrimazole to the affected area. Don’t wash your hands after applying it, as this will remove the medication. Use it twice a day, in the morning and evening.

It’s best to keep your hands dry whenever possible, as fungi thrive in damp environments. You should also avoid manicures and cosmetic hand products until your infection has cleared.