Mirvaso ®
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Reviewed on Nov 7, 2025. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Registered with GPhC (No. 2241935) Next review due on Nov 07, 2028.
Dr Alexandra Cristina Cowell

Last updated on Nov 07, 2025.

A daily gel to calm the flushing caused by rosacea.

Mirvaso is a topical gel that you’ll usually apply to areas affected by rosacea once per day. It helps to reduce persistent redness and flushing caused by rosacea.

Price checker

3mg/g gel
$1,329.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $1,329.95
    Save $0.00 each order
Mirvaso Brimonidine

What is Mirvaso?

It’s a gel that you apply to rosacea-affected areas every day to reduce redness. It’s a type of medicine called an alpha-adrenergic receptor agonist. This means they bind to receptors (called alpha-adrenergic receptors) found on the smooth muscles in the blood vessels near the surface of your skin.

How does Mirvaso work?

The redness that characterizes rosacea is caused by dilated (widened) blood vessels near the surface of your skin. Mirvaso binds to the receptors on the smooth muscle surrounding these blood vessels, causing the muscles to contract. This narrows the dilated blood vessels, limiting the amount of blood flowing through them. This should help to reduce the redness caused by Rosacea.[1]

How do Mirvaso doses work?

Mirvaso comes in one dosage – a 0.33% gel. This means that for each gram of gel, it contains 3.3 mg of Mirvaso.

What is Mirvaso’s active ingredient?

Mirvaso’s active ingredient is brimonidine. It’s an alpha-adrenergic receptor agonist. This means it binds to alpha-adrenergic receptors on the smooth muscle around blood vessels close to the surface of your skin. This constricts these blood vessels, which helps reduce redness caused by rosacea.[1]

Treated trusted source:

  1. Grobel, H. Murphy, S.A. (2018). Acne Vulgaris and Acne Rosacea in Integrative Medicine. 4th ed.
Dr Alexandra Cristina Cowell 23938
This page was medically reviewed by Dr Alexandra Cristina Cowell on November 07, 2025. Next review due on November 07, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Mirvaso Brimonidine

How to take Mirvaso

You’ll typically apply Mirvaso to the affected areas once per day. You’ll start by applying a very small amount of gel during the first week (about a pea sized amount), or as instructed by your healthcare provider.

If your symptoms don’t get better (or only very slightly better), you can gradually increase the amount of gel after the first week. Make sure you spread it smoothly in a very thin layer over the affected area. You shouldn’t use more than one gram (five pea sized amounts) each day.

Dr Alexandra Cristina Cowell 23938
This page was medically reviewed by Dr Alexandra Cristina Cowell on November 07, 2025. Next review due on November 07, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Mirvaso Brimonidine

Mirvaso isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.

Mirvaso Brimonidine

Mirvaso: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Are there any Mirvaso alternatives?

Answer:
Mirvaso treats the redness caused by rosacea. But if you get bumps or lesions as part of rosacea, you may need to use an alternative or additional treatment.

Azelaic acid is a topical treatment for rosacea that has anti-inflammatory properties, which should help to reduce the bumps and spots caused by rosacea. But if the spots are filled with yellow liquid (pus), it could be a sign of bacterial infection. In this case, oral antibiotics like Doxycycline could be a good option. They prevent the bacteria from growing and spreading, as well as helping to reduce redness.

How effective is Mirvaso?

Answer:
Mirvaso has proven to be an effective treatment for rosacea in clinical trials. One study found that brimodine gel was significantly more effective than placebo at reducing rosacea symptoms. 56.7%-70.9% of people had at least a one-grade improvement to their rosacea, compared to 29.7-32.8% in the placebo group. Brimonidine also displayed significantly greater efficacy than placebo after 30 minutes, one day, 15 days, and 29 days of treatment.[1]

Do I need a prescription for Mirvaso?

Answer:
Yes. A doctor will need to check to make sure Mirvaso is the right treatment for you before you use it. Mirvaso may not be suitable if you have open cuts on your face, you have heart or blood pressure problems, or you have kidney or liver problems, for example.

How long does it take Mirvaso to work?

Answer:
Mirvaso is a fast-acting treatment for rosacea. Research shows that in 28% of people, a noticeable effect is seen within 30 minutes. It reaches its peak around three hours after application, and continues to be effective over a 12-hour period.[2]

What should I do if I make a mistake when taking Mirvaso?

Answer:
If you accidentally apply too much Mirvaso in one day, you may get skin irritation or other Mirvaso side effects where it was applied. If you repeatedly use too much Mirvaso, you could experience low blood pressure, or drowsiness.

If you accidentally swallow Mirvaso, contact your doctor or go to the hospital immediately.

Mirvaso works as you apply it on a daily basis. So if you forget to use Mirvaso, it won’t help reduce redness caused by rosacea that day. Never use a double dose of Mirvaso to make up for missing one.

Are there any Mirvaso side effects?

Answer:
Mirvaso isn’t right for everyone, and some people may get side effects while using it (but not everyone will). It’s uncommon, but if you experience:

  • severe skin irritation

  • severe inflammation

  • skin rash or pain

  • dry skin

  • warm skin

  • tingling or pins and needles

  • or swelling of the face


stop using Mirvaso right away and speak to your physician.

The most common Mirvaso side effects you’re likely to experience (affecting up to one in 10 people) include:

  • Flushing (redness)

  • Excessive whitening of the skin where it’s applied

  • Burning or itching where you applied it.


This isn’t a comprehensive list of all of Mirvaso’s side effects. For more information, speak to your doctor or take a look at the patient information leaflet.

Can I get Mirvaso through private health insurance?

Answer:
It’s always best to check the formulary of your health insurance plan, to see which drugs it covers. Insurance plans may only cover part of the cost of Mirvaso, and only provide coverage if you obtain it from specific healthcare providers.

But if you can’t get Mirvaso through your health insurance, you should still be able to get it through a private pharmacy service.

Treated trusted source:

  1. Jackson, J.M. et al. (2015). The role of brimonidine tartrate gel in the treatment of rosacea. Clinical, Cosmetic and Investigational Dermatology. 8. pp. 529-538.
  2. NICE. (2014). Facial erythema of rosacea: brimonidine tartrate gel. National Institute for Health Care and Excellence. 8 July.

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